Sensitivity of dose-finding studies to observation errors

Contemporary Clinical Trials

Volumn 30, Issue 6, 2009, Pages 523-530

  Zohar, Sarah ^a   O'Quigley, John ^b  

^a SAINT LOUIS HOSPITAL   (France)

^b INSERM   (France)

Author keywords

Continual reassessment method; Dose finding; Grouped up and down; Sensitivity; Toxicity

Indexed keywords

ARTICLE; BIOMETRY; HUMAN; MAXIMUM TOLERATED DOSE; MEDICAL ERROR; OBSERVATIONAL STUDY; SIMULATION;

BAYES THEOREM; CLINICAL TRIALS, PHASE I AS TOPIC; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; MAXIMUM TOLERATED DOSE; MODELS, STATISTICAL; OBSERVER VARIATION; REPRODUCIBILITY OF RESULTS; RESEARCH DESIGN;

EID: 70350569812     PISSN: 15517144     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cct.2009.06.008     Document Type: Article

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