메뉴 건너뛰기




Volumn 29, Issue 21, 2009, Pages 5639-5644

Regulating the activity of class II transactivator by posttranslational modifications: Exploring the possibilities

Author keywords

[No Author keywords available]

Indexed keywords

TRANSACTIVATOR CLASS 2 PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 70350538958     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.00661-09     Document Type: Article
Times cited : (31)

References (41)
  • 1
    • 1642396348 scopus 로고    scopus 로고
    • Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta
    • Abbas, T., D. White, L. Hui, K. Yoshida, D. A. Foster, and J. Bargonetti. 2004. Inhibition of human p53 basal transcription by down-regulation of protein kinase Cdelta. J. Biol. Chem. 279:9970-9977.
    • (2004) J. Biol. Chem. , vol.279 , pp. 9970-9977
    • Abbas, T.1    White, D.2    Hui, L.3    Yoshida, K.4    Foster, D.A.5    Bargonetti, J.6
  • 2
    • 47749140333 scopus 로고    scopus 로고
    • SIRT1 Regulates Circadian Clock Gene Expression through PER2 Deacetylation
    • DOI 10.1016/j.cell.2008.06.050, PII S0092867408008374
    • Asher, G., D. Gatfield, M. Stratmann, H. Reinke, C. Dibner, F. Kreppel, R. Mostoslavsky, F. W. Alt, and U. Schibler. 2008. SIRT1 regulates circadian clock gene expression through PER2 deacetylation. Cell 134:317-328. (Pubitemid 352024391)
    • (2008) Cell , vol.134 , Issue.2 , pp. 317-328
    • Asher, G.1    Gatfield, D.2    Stratmann, M.3    Reinke, H.4    Dibner, C.5    Kreppel, F.6    Mostoslavsky, R.7    Alt, F.W.8    Schibler, U.9
  • 3
    • 33645294156 scopus 로고    scopus 로고
    • Interferon-gamma induces major histocompatibility class II transactivator (CIITA), which mediates collagen repression and major histocompatibility class II activation by human aortic smooth muscle cells
    • Buttice, G., J. Miller, L. Wang, and B. D. Smith. 2006. Interferon-gamma induces major histocompatibility class II transactivator (CIITA), which mediates collagen repression and major histocompatibility class II activation by human aortic smooth muscle cells. Circ. Res. 98:472-479.
    • (2006) Circ. Res. , vol.98 , pp. 472-479
    • Buttice, G.1    Miller, J.2    Wang, L.3    Smith, B.D.4
  • 4
    • 0033082169 scopus 로고    scopus 로고
    • A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome
    • Cressman, D. E., K. C. Chin, D. J. Taxman, and J. P. Ting. 1999. A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome. Immunity 10:163-171.
    • (1999) Immunity , vol.10 , pp. 163-171
    • Cressman, D.E.1    Chin, K.C.2    Taxman, D.J.3    Ting, J.P.4
  • 6
    • 0035284888 scopus 로고    scopus 로고
    • Cutting edge: The class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression
    • Gourley, T. S., and C. H. Chang. 2001. Cutting edge: the class II transactivator prevents activation-induced cell death by inhibiting Fas ligand gene expression. J. Immunol. 166:2917-2921.
    • (2001) J. Immunol. , vol.166 , pp. 2917-2921
    • Gourley, T.S.1    Chang, C.H.2
  • 7
    • 2942744668 scopus 로고    scopus 로고
    • Serine residues 286, 288, and 293 within the CIITA: A mechanism for down-regulating CIITA activity through phosphorylation
    • Greer, S. F., J. A. Harton, M. W. Linhoff, C. A. Janczak, J. P. Ting, and D. E. Cressman. 2004. Serine residues 286, 288, and 293 within the CIITA: a mechanism for down-regulating CIITA activity through phosphorylation. J. Immunol. 173:376-383.
    • (2004) J. Immunol. , vol.173 , pp. 376-383
    • Greer, S.F.1    Harton, J.A.2    Linhoff, M.W.3    Janczak, C.A.4    Ting, J.P.5    Cressman, D.E.6
  • 8
    • 0242708771 scopus 로고    scopus 로고
    • Enhancement of CIITA transcriptional function by ubiquitin
    • Greer, S. F., E. Zika, B. Conti, X. S. Zhu, and J. P. Ting. 2003. Enhancement of CIITA transcriptional function by ubiquitin. Nat. Immunol. 4:1074-1082.
    • (2003) Nat. Immunol. , vol.4 , pp. 1074-1082
    • Greer, S.F.1    Zika, E.2    Conti, B.3    Zhu, X.S.4    Ting, J.P.5
  • 9
    • 0035914430 scopus 로고    scopus 로고
    • The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator
    • Harton, J. A., E. Zika, and J. P. Ting. 2001. The histone acetyltransferase domains of CREB-binding protein (CBP) and p300/CBP-associated factor are not necessary for cooperativity with the class II transactivator. J. Biol. Chem. 276:38715-38720.
    • (2001) J. Biol. Chem. , vol.276 , pp. 38715-38720
    • Harton, J.A.1    Zika, E.2    Ting, J.P.3
  • 10
    • 51249090739 scopus 로고    scopus 로고
    • Current approaches for global post-translational modification discovery and mass spectrometric analysis
    • Hoffman, M. D., M. J. Sniatynski, and J. Kast. 2008. Current approaches for global post-translational modification discovery and mass spectrometric analysis. Anal. Chim. Acta 627:50-61.
    • (2008) Anal. Chim. Acta , vol.627 , pp. 50-61
    • Hoffman, M.D.1    Sniatynski, M.J.2    Kast, J.3
  • 11
    • 36749010218 scopus 로고    scopus 로고
    • The Age of Crosstalk: Phosphorylation, Ubiquitination, and Beyond
    • DOI 10.1016/j.molcel.2007.11.019, PII S1097276507007988
    • Hunter, T. 2007. The age of crosstalk: phosphorylation, ubiquitination, and beyond. Mol. Cell 28:730-738. (Pubitemid 350217067)
    • (2007) Molecular Cell , vol.28 , Issue.5 , pp. 730-738
    • Hunter, T.1
  • 13
    • 34047194383 scopus 로고    scopus 로고
    • Crippling p53 activities via knock-in mutations in mouse models
    • DOI 10.1038/sj.onc.1210278, PII 1210278
    • Iwakuma, T., and G. Lozano. 2007. Crippling p53 activities via knock-in mutations in mouse models. Oncogene 26:2177-2184. (Pubitemid 46536640)
    • (2007) Oncogene , vol.26 , Issue.15 , pp. 2177-2184
    • Iwakuma, T.1    Lozano, G.2
  • 14
    • 59149095347 scopus 로고    scopus 로고
    • HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells
    • Kong, X., M. Fang, P. Li, F. Fang, and Y. Xu. 2009. HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells. J. Mol. Cell. Cardiol. 46:292-299.
    • (2009) J. Mol. Cell. Cardiol. , vol.46 , pp. 292-299
    • Kong, X.1    Fang, M.2    Li, P.3    Fang, F.4    Xu, Y.5
  • 15
    • 0034741278 scopus 로고    scopus 로고
    • PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF
    • Leung, C. H., W. Lam, W. J. Zhuang, N. S. Wong, M. S. Yang, and W. F. Fong. 2001. PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF. Biochem. Biophys. Res. Commun. 285:283-288.
    • (2001) Biochem. Biophys. Res. Commun. , vol.285 , pp. 283-288
    • Leung, C.H.1    Lam, W.2    Zhuang, W.J.3    Wong, N.S.4    Yang, M.S.5    Fong, W.F.6
  • 16
    • 0034948954 scopus 로고    scopus 로고
    • Downregulation of CIITA function by protein kinase A (PKA)-mediated phosphorylation: Mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines
    • Li, G., J. A. Harton, X. Zhu, and J. P.-Y. Ting. 2001. Downregulation of CIITA function by protein kinase A (PKA)-mediated phosphorylation: mechanism of prostaglandin E, cyclic AMP, and PKA inhibition of class II major histocompatibility complex expression in monocytic lines. Mol. Cell. Biol. 21:4626-4635.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 4626-4635
    • Li, G.1    Harton, J.A.2    Zhu, X.3    Ting, J.P.-Y.4
  • 17
    • 59449091869 scopus 로고    scopus 로고
    • CIITA versus IFN-gamma induced MHC class II expression in head and neck cancer cells
    • Meissner, M., T. L. Whiteside, R. Kaufmann, and B. Seliger. 2009. CIITA versus IFN-gamma induced MHC class II expression in head and neck cancer cells. Arch. Dermatol. Res. 301:189-193.
    • (2009) Arch. Dermatol. Res. , vol.301 , pp. 189-193
    • Meissner, M.1    Whiteside, T.L.2    Kaufmann, R.3    Seliger, B.4
  • 19
    • 0036839436 scopus 로고    scopus 로고
    • Modulation of gene expression by the MHC class II transactivator
    • Nagarajan, U. M., A. Bushey, and J. M. Boss. 2002. Modulation of gene expression by the MHC class II transactivator. J. Immunol. 169:5078-5088. (Pubitemid 35217177)
    • (2002) Journal of Immunology , vol.169 , Issue.9 , pp. 5078-5088
    • Nagarajan, U.M.1    Bushey, A.2    Boss, J.M.3
  • 20
    • 34447540331 scopus 로고    scopus 로고
    • Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII
    • Nikodemova, M., J. J. Watters, S. J. Jackson, S. K. Yang, and I. D. Duncan. 2007. Minocycline down-regulates MHC II expression in microglia and macrophages through inhibition of IRF-1 and protein kinase C (PKC)alpha/betaII. J. Biol. Chem. 282:15208-15216.
    • (2007) J. Biol. Chem. , vol.282 , pp. 15208-15216
    • Nikodemova, M.1    Watters, J.J.2    Jackson, S.J.3    Yang, S.K.4    Duncan, I.D.5
  • 21
    • 4644354120 scopus 로고    scopus 로고
    • Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression
    • Nozell, S., Z. Ma, C. Wilson, R. Shah, and E. N. Benveniste. 2004. Class II major histocompatibility complex transactivator (CIITA) inhibits matrix metalloproteinase-9 gene expression. J. Biol. Chem. 279:38577-38589.
    • (2004) J. Biol. Chem. , vol.279 , pp. 38577-38589
    • Nozell, S.1    Ma, Z.2    Wilson, C.3    Shah, R.4    Benveniste, E.N.5
  • 22
    • 0035106263 scopus 로고    scopus 로고
    • Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250
    • Raval, A., T. K. Howcroft, J. D. Weissman, S. Kirshner, X. S. Zhu, K. Yokoyama, J. Ting, and D. S. Singer. 2001. Transcriptional coactivator, CIITA, is an acetyltransferase that bypasses a promoter requirement for TAF(II)250. Mol. Cell 7:105-115.
    • (2001) Mol. Cell , vol.7 , pp. 105-115
    • Raval, A.1    Howcroft, T.K.2    Weissman, J.D.3    Kirshner, S.4    Zhu, X.S.5    Yokoyama, K.6    Ting, J.7    Singer, D.S.8
  • 23
    • 0042476378 scopus 로고    scopus 로고
    • N-terminal destruction signals lead to rapid degradation of the major histocompatibility complex class II transactivator CIITA
    • Schnappauf, F., S. B. Hake, M. M. Camacho Carvajal, S. Bontron, B. Lisowska-Grospierre, and V. Steimle. 2003. N-terminal destruction signals lead to rapid degradation of the major histocompatibility complex class II transactivator CIITA. Eur. J. Immunol. 33:2337-2347.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2337-2347
    • Schnappauf, F.1    Hake, S.B.2    Camacho Carvajal, M.M.3    Bontron, S.4    Lisowska-Grospierre, B.5    Steimle, V.6
  • 24
    • 0034284190 scopus 로고    scopus 로고
    • MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300
    • Sisk, T. J., T. Gourley, S. Roys, and C. H. Chang. 2000. MHC class II transactivator inhibits IL-4 gene transcription by competing with NF-AT to bind the coactivator CREB binding protein (CBP)/p300. J. Immunol. 165:2511-2517.
    • (2000) J. Immunol. , vol.165 , pp. 2511-2517
    • Sisk, T.J.1    Gourley, T.2    Roys, S.3    Chang, C.H.4
  • 25
    • 0141729438 scopus 로고    scopus 로고
    • Phosphorylation of class II transactivator regulates its interaction ability and transactivation function
    • Sisk, T. J., K. Nickerson, R. P. Kwok, and C. H. Chang. 2003. Phosphorylation of class II transactivator regulates its interaction ability and transactivation function. Int. Immunol. 15:1195-1205.
    • (2003) Int. Immunol. , vol.15 , pp. 1195-1205
    • Sisk, T.J.1    Nickerson, K.2    Kwok, R.P.3    Chang, C.H.4
  • 26
    • 0033767150 scopus 로고    scopus 로고
    • Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes
    • Spilianakis, C., J. Papamatheakis, and A. Kretsovali. 2000. Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes. Mol. Cell. Biol. 20:8489-8498.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8489-8498
    • Spilianakis, C.1    Papamatheakis, J.2    Kretsovali, A.3
  • 27
    • 0027490172 scopus 로고
    • Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)
    • DOI 10.1016/0092-8674(93)90685-J
    • Steimle, V., L. A. Otten, M. Zufferey, and B. Mach. 1993. Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome). Cell 75:135-146. (Pubitemid 23306027)
    • (1993) Cell , vol.75 , Issue.1 , pp. 135-146
    • Steimle, V.1    Otten, L.A.2    Zufferey, M.3    Mach, B.4
  • 28
    • 0033998024 scopus 로고    scopus 로고
    • Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis
    • Suter, T., U. Malipiero, L. Otten, B. Ludewig, A. Muelethaler-Mottet, B. Mach, W. Reith, and A. Fontana. 2000. Dendritic cells and differential usage of the MHC class II transactivator promoters in the central nervous system in experimental autoimmune encephalitis. Eur. J. Immunol. 30:794-802.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 794-802
    • Suter, T.1    Malipiero, U.2    Otten, L.3    Ludewig, B.4    Muelethaler-Mottet, A.5    Mach, B.6    Reith, W.7    Fontana, A.8
  • 29
    • 18144369681 scopus 로고    scopus 로고
    • The CATERPILLER family: An ancient family of immune/apoptotic proteins
    • Ting, J. P., and K. L. Williams. 2005. The CATERPILLER family: an ancient family of immune/apoptotic proteins. Clin. Immunol. 115:33-37.
    • (2005) Clin. Immunol. , vol.115 , pp. 33-37
    • Ting, J.P.1    Williams, K.L.2
  • 30
    • 0037107381 scopus 로고    scopus 로고
    • Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters
    • DOI 10.1093/emboj/cdf557
    • Tosi, G., N. Jabrane-Ferrat, and B. M. Peterlin. 2002. Phosphorylation of CIITA directs its oligomerization, accumulation and increased activity on MHCII promoters. EMBO J. 21:5467-5476. (Pubitemid 35231026)
    • (2002) EMBO Journal , vol.21 , Issue.20 , pp. 5467-5476
    • Tosi, G.1    Jabrane-Ferrat, N.2    Peterlin, B.M.3
  • 31
    • 0021076854 scopus 로고
    • The bare lymphocyte syndrome: Immunodeficiency resulting from the lack of expression of HLA antigens
    • Touraine, J. L., and H. Betuel. 1983. The bare lymphocyte syndrome: immunodeficiency resulting from the lack of expression of HLA antigens. Birth Defects Orig. Artic. Ser. 19:83-85.
    • (1983) Birth Defects Orig. Artic. Ser. , vol.19 , pp. 83-85
    • Touraine, J.L.1    Betuel, H.2
  • 32
    • 44049108827 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase ERK1/2 regulates the class II transactivator
    • Voong, L. N., A. R. Slater, S. Kratovac, and D. E. Cressman. 2008. Mitogen-activated protein kinase ERK1/2 regulates the class II transactivator. J. Biol. Chem. 283:9031-9039.
    • (2008) J. Biol. Chem. , vol.283 , pp. 9031-9039
    • Voong, L.N.1    Slater, A.R.2    Kratovac, S.3    Cressman, D.E.4
  • 34
    • 38349158365 scopus 로고    scopus 로고
    • CIITA mediates interferon-gamma repression of collagen transcription through phosphorylation-dependent interactions with co-repressor molecules
    • Xu, Y., J. A. Harton, and B. D. Smith. 2008. CIITA mediates interferon-gamma repression of collagen transcription through phosphorylation-dependent interactions with co-repressor molecules. J. Biol. Chem. 283:1243-1256.
    • (2008) J. Biol. Chem. , vol.283 , pp. 1243-1256
    • Xu, Y.1    Harton, J.A.2    Smith, B.D.3
  • 35
    • 4944225950 scopus 로고    scopus 로고
    • Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon gamma (IFN-gamma)
    • DOI 10.1074/jbc.M404174200
    • Xu, Y., L. Wang, G. Buttice, P. K. Sengupta, and B. D. Smith. 2004. Major histocompatibility class II transactivator (CIITA) mediates repression of collagen (COL1A2) transcription by interferon gamma (IFN-gamma). J. Biol. Chem. 279:41319-41332. (Pubitemid 39328146)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.40 , pp. 41319-41332
    • Xu, Y.1    Wang, L.2    Buttice, G.3    Sengupta, P.K.4    Smith, B.D.5
  • 36
    • 0032938514 scopus 로고    scopus 로고
    • Lack of class II transactivator causes severe deficiency of HLA-DR expression in small cell lung cancer
    • DOI 10.1002/(SICI)1096-9896(199901)187:2<191::AID-PATH206>3.0.CO;2- 3
    • Yazawa, T., H. Kamma, M. Fujiwara, M. Matsui, H. Horiguchi, H. Satoh, M. Fujimoto, K. Yokoyama, and T. Ogata. 1999. Lack of class II transactivator causes severe deficiency of HLA-DR expression in small cell lung cancer. J. Pathol. 187:191-199. (Pubitemid 29037048)
    • (1999) Journal of Pathology , vol.187 , Issue.2 , pp. 191-199
    • Yazawa, T.1    Kamma, H.2    Fujiwara, M.3    Matsui, M.4    Horiguchi, H.5    Satoh, H.6    Fujimoto, M.7    Yokoyama, K.8    Ogata, T.9
  • 37
    • 39149116674 scopus 로고    scopus 로고
    • NLR, the nucleotide-binding domain leucine-rich repeat containing gene family
    • Ye, Z., and J. P. Ting. 2008. NLR, the nucleotide-binding domain leucine-rich repeat containing gene family. Curr. Opin. Immunol. 20:3-9.
    • (2008) Curr. Opin. Immunol. , vol.20 , pp. 3-9
    • Ye, Z.1    Ting, J.P.2
  • 38
    • 2142660854 scopus 로고    scopus 로고
    • Cathepsin E: A Novel Target for Regulation by Class II Transactivator
    • Yee, C. S., Y. Yao, P. Li, M. J. Klemsz, J. S. Blum, and C. H. Chang. 2004. Cathepsin E: a novel target for regulation by class II transactivator. J. Immunol. 172:5528-5534. (Pubitemid 38542054)
    • (2004) Journal of Immunology , vol.172 , Issue.9 , pp. 5528-5534
    • Yee, C.S.K.1    Yao, Y.2    Li, P.3    Klemsz, M.J.4    Blum, J.S.5    Chang, C.-H.6
  • 41
    • 28044431831 scopus 로고    scopus 로고
    • Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression
    • Zika, E., L. Fauquier, L. Vandel, and J. P. Ting. 2005. Interplay among coactivator-associated arginine methyltransferase 1, CBP, and CIITA in IFN-gamma-inducible MHC-II gene expression. Proc. Natl. Acad. Sci. USA 102:16321-16326.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 16321-16326
    • Zika, E.1    Fauquier, L.2    Vandel, L.3    Ting, J.P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.