A comparison of the neuroprotective efficacy of newly developed oximes (K117, K127) and currently available oxime (obidoxime) in tabun-poisoned rats

Toxicology Mechanisms and Methods

Volumn 19, Issue 3, 2009, Pages 232-238

  Kassa, Jiri ^a   Karasova, Jana Zdarova ^a   Musilek, Kamil ^a   Kuca, Kamil ^b   Jung, And Young Sik ^c  

^a UNIVERSITY OF DEFENCE   (Czech Republic)

^b UNIVERSITY OF DEFENCE   (Czech Republic)

^c Korea Research Institute of Chemical Technology   (South Korea)

Author keywords

Atropine; Functional observational battery; Neurotoxicity; Oximes; Tabun

Indexed keywords

[1 (4 HYDROXYIMINOMETHYLPYRIDINIUM) 5 (4 CARBAMOYLPYRIDINIUM) 3 OXAPENTANE DIBROMIDE]; [1,5 BIS(4 HYDROXYIMINOMETHYLPYRIDINIUM) 3 OXAPENTANE DIBROMIDE]; ANTIDOTE; ATROPINE; BIS(PYRIDINIUM OXIME) DERIVATIVE; K 117; K 127; OBIDOXIME; TABUN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG EFFICACY; INTOXICATION; LETHAL DOSE; MALE; MOTOR ACTIVITY; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; OBSERVATIONAL STUDY; PRIORITY JOURNAL; RAT; TABUN INTOXICATION;

ANIMALS; CHEMICAL WARFARE AGENTS; CHOLINESTERASE INHIBITORS; MALE; MOTOR ACTIVITY; NEUROPROTECTIVE AGENTS; OXIMES; PHOSPHORIC ACID ESTERS; PYRIDINIUM COMPOUNDS; RATS; RATS, WISTAR;

RATTUS;

EID: 70350514299     PISSN: 15376516     EISSN: 15376524     Source Type: Journal    
DOI: 10.1080/15376510802455362     Document Type: Article

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