Discovery of new natural products by intact-cell mass spectrometry and lc-spe-nmr: malbranpyrroles, novel polyketides from thermophilic fungus malbranchea sulfurea

Chemistry - A European Journal

Volumn 15, Issue 43, 2009, Pages 11573-11580

  Yang, Yu Liang ^a   Liao, Wen Ying ^b,c   Liu, Wan Yun ^a   Liaw, Chih Chuang ^b,d   Shen, Chia Ning ^c   Huang, Zih You ^a   Wu, Shih Hsiung ^a  

^a INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^b CHINA MEDICAL UNIVERSITY   (Taiwan)

^c GENOMICS RESEARCH CENTER   (Taiwan)

^d NATIONAL CHUNG HSING UNIVERSITY   (Taiwan)

Author keywords

Malbranchea sulfurea mass spectrometry; Natural products; Nmr spectroscopy; Polyketides

Indexed keywords

BIOSYNTHETIC PATHWAY; CANCER CELL LINES; CELL MASS; CHLORINE ATOM; CONJUGATED SYSTEMS; CYTOTOXIC; DESORPTION/IONIZATION ON SILICONS; FEEDING EXPERIMENTS; MALBRANCHEA SULFUREA MASS SPECTROMETRY; NATURAL PRODUCTS; NMR SPECTROSCOPY; PHARMACOPHORES; POLYKETIDES; STRUCTURAL DETERMINATION; THERMOPHILIC FUNGUS;

AMINES; AMINO ACIDS; CELL CULTURE; CELL MEMBRANES; CHLORINE; DESORPTION; FUNGI; ISOTOPES; MASS SPECTROMETERS; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; ORGANIC ACIDS;

CYTOTOXICITY;

BIOLOGICAL PRODUCT; MACROLIDE; PYRROLE DERIVATIVE;

ARTICLE; CHEMISTRY; CONFORMATION; FUNGUS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLID PHASE EXTRACTION; TUMOR CELL LINE;

BIOLOGICAL PRODUCTS; CELL LINE, TUMOR; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FUNGI; HUMANS; MACROLIDES; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MOLECULAR CONFORMATION; PYRROLES; SOLID PHASE EXTRACTION;

EID: 70350509072     PISSN: 09476539     EISSN: 15213765     Source Type: Journal    
DOI: 10.1002/chem.200901556     Document Type: Article

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