A comparative study of the antioxidant properties of two different species of ocimum of southern africa on alcohol-induced oxidative stress

Journal of Medicinal Food

Volumn 12, Issue 5, 2009, Pages 1154-1158

  George, S ^a   Chaturvedi, P ^b  

^a BOTSWANA COLLEGE OF AGRICULTURE   (Botswana)

^b UNIVERSITY OF BOTSWANA   (Botswana)

Author keywords

Antioxidant properties; Ethanol induced hepatoxicity; Ocimum canum; Ocimum gratissimum

Indexed keywords

ALANINE AMINOTRANSFERASE; ALCOHOL; ALPHA TOCOPHEROL; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASE; CATALASE; GLUTATHIONE; METHANOL; OCIMUM CANUM EXTRACT; OCIMUM GRATISSIMUM EXTRACT; PLANT EXTRACT; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIOXIDANT ACTIVITY; ARTICLE; BASIL; CHEMICAL ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; ENZYME ACTIVITY; LIVER CELL; LIVER TOXICITY; MALE; NONHUMAN; OCIMUM CANUM; OCIMUM GRATISSIMUM; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SOUTH AFRICA;

AFRICA; ALANINE TRANSAMINASE; ANIMALS; ANTIOXIDANTS; ASCORBIC ACID; ASPARTATE AMINOTRANSFERASES; CATALASE; DRUG-INDUCED LIVER INJURY; ETHANOL; GLUTATHIONE; LIVER; MALE; OCIMUM; OXIDATIVE STRESS; PLANT EXTRACTS; RANDOM ALLOCATION; RATS; RATS, WISTAR; SUPEROXIDE DISMUTASE; THIOBARBITURIC ACID REACTIVE SUBSTANCES; VITAMIN E;

OCIMUM; OCIMUM CANUM; OCIMUM GRATISSIMUM; RATTUS; RATTUS NORVEGICUS;

EID: 70350502816     PISSN: 1096620X     EISSN: None     Source Type: Journal    
DOI: 10.1089/jmf.2008.0066     Document Type: Article

References (29)

1. Lieber CS: Ethanol metabolism, cirrhosis and alcoholism. Clin Chim Acta 1997;257:59-84.
2. Nadiger HA, Marcus SR, Chandrakala MV: Lipid peroxidation and ethanol toxicity in rat brain: Effect of vitamin E deficiency and supplementation. IRCS Med Sci Res 1988;16: 1273-1274.
3. Montoliu C, Vallès S, Renau-Piqueras J, Guerri C: Ethanolinduced oxygen radical formation and lipid peroxidation in rat brain. Effect of chronic alcohol consumption. J Neurochem 1994; 63:1855-1862.
4. Zima T, Fialova L, Mestek O, Janebova M, Crkovska J, Malbohan I, Stipek S, Mikulikova L, Popov P: Oxidative stress, metabolism of ethanol and alcohol related disease. J Biomed Sci 2001;8:59-70.
5. Bandhopadhy U, Das D, Banerjee KR: Reactive oxygen species: Oxidative damage and pathogenesis. Curr Sci 1999;77:658-665.
6. Lieber CS: Cytochrome P-4502E1: Its physiological and pathological role. Physiol Rev 1997;77:517-544.
7. Chatterjee TK: Medicinal plants with hepatoprotective properties In: Herbal Options, 3rd ed. Books & Allied (P) Ltd., Calcutta, 2000, pp. 135-137.
8. Karthikayan K, Gunasekaran P, Ramamurthy N, Govindaswamy S: Anticancer activity of Ocimum sanctum. Pharmaceut Biol 1999;37:285-290.
9. Manikandan P, Murugan RS, Abbas H, Abraham SK, Nagini S: Ocimum sanctum Linn. (holy basil) ethanolic leaf extract protects against 7,12-dimethylbenz[a] anthracene-induced genotoxicity, oxidative stress, and imbalance in xenobiotic-metabolizing enzymes. J Med Food 2007;10:495-502.
10. Beric T, Nicolic B, Stanojevic J, Vucovic-Gacic B, Knezevic-Vukcevic J: Protective effect of basil (Ocimum basilicum L.) against oxidative DNA damage and mutagenesis. Food Chem Toxicol 2007;46:724-732.
11. Veronica R: Common Wild Flowers of the Okawango Delta; Medicinal Uses and Nutritional Value. Briza Publication, Arcadia, South Africa, 1998, pp. 100-102.
12. Martins AP, Salgueiro LR, Vila R, Tomi F, Canigueral S, Casanova J, da Cunha AP, Adzet T: Composition of the essential oils of Ocimum canum, O. gratissimum and O. minimum. Planta Med 1999;65:187-189.
13. Chaturvedi P, George S, John A: Preventive and protective effects of wild basil in ethanol induced liver toxicity in rats. Br J Biomed Sci 2007;64:10-12.
14. Niehaus WG, Samuelson B: Formation of MDA from phospholipid arachidonate during microsomal lipid peroxidation. Eur J Biochem 1986;6:126-130.
15. Ellman GL: Tissue sulfhydryl groups. Arch Biochem Biophys 1959;82:70-77.
16. Kakkar P, Das B, Viswanathan PN: A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem Biophys 1984;21:130-132.
17. Bisswanger H: Practical Enzymology. Wiley-VCH Verlag GmbH & Co., Weinheim, 2004, p. 79.
18. Martinek RG: Method for the determination of vitamin E (total tocopherols) in serum. Clin Chem 1964;10:1078-1086.
19. Roe JH: Chemical determination of ascorbic, deascorbic and diketgulonic acids. In: Methods of Biochemical Analysis,Vol. 1 (Glick D, ed.). Interscience Publishers, New York, 1961, pp. 115-139.
20. Lowry OH, Rosebrough NJ, Farr AL, Randall RJ: Protein measurement with the Folin phenol reagent. J Biol Chem 1951;93: 265-275.
21. Viani P, Cervato G, Fiorilli A, Cestaro B: Age-related differences in synaptosomal peroxidative damage and membrane properties. J Neurochem 1991;56:253-258.
22. Sally R, Tredger JM, Willam R: Drugs and liver. Biopharm Drugs Dispos 1991;12:251-259.
23. Himmerich H, Anghelescu I, Klawe C, Szegedi A: Vitamin B12 and hepatic enzyme serum levels correlate in male alcohol dependent patients. Alcohol Alcohol 2001;36:26-28.
24. O'Brien PJ, Slaughter MR, Swain A, Birmingham JM, Greenhill RW, Elcock F, Bugelski PL: Repeated acetaminophen dosing in rats: Adaptation of hepatic antioxidant system. Hum Exp Toxicol 2000;19:277-283.
25. Prescott LF: Glutathione: A protective mechanism against hepatotoxicity. Biochem Soc Trans 1982;10:84-85.
26. Jaya DS, Augustine J, Menon VP: Role of lipid peroxides, glutathione and antiperoxidative enzymes in alcohol and drug toxicity. Indian J Exp Biol 1993;31:453-459.
27. Gerster H: b-Carotene, vitamin E and vitamin C in different stages of experimental carcinogenesis. Eur J Clin Nutr 1995;49: 155-168.
28. Scott MD, Lubiu BH, Zuo L, Kypers FA: Erythrocyte defence against hydrogen peroxide: Preeminent importance of catalase. J Lab Clin Med 1991;118:7-16.
29. Pigeolot E, Corbisier P, Houbion A, Lambert D, Michiels C, Raes M, Zachary MO, Ramacle J: Glutathione peroxidase, superoxide dismutase and calatase inactivation by peroxides and oxygen derived radicals. Mech Age Dev 1990;51:283-297.