The MitCHAP-60 disease is due to entropic destabilization of the human mitochondrial Hsp60 oligomer

Journal of Biological Chemistry

Volumn 284, Issue 41, 2009, Pages 28198-28203

  Parnas, Avital ^a   Nadler, Michal ^b   Nisemblat, Shahar ^a   Horovitz, Amnon ^b   Mandel, Hanna ^c   Azem, Abdussalam ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^c TECHNION ISRAEL INSTITUTE OF TECHNOLOGY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

ATP-ASE ACTIVITY; BACTERIAL PROTEIN; CHAPERONE FUNCTIONS; ENTROPIC DESTABILIZATION; HEAT SHOCK PROTEIN; IN-VITRO; MITOCHONDRIAL PROTEIN; MOLECULAR BASIS; MUTANT PROTEINS; NEURODEGENERATIVE DISORDERS; OLIGOMERIC STRUCTURE; POINT MUTATIONS; PROTEIN CONCENTRATIONS; REFOLDING; WILD TYPES;

AMINES; AMINO ACIDS; ESCHERICHIA COLI; ORGANIC ACIDS;

PROTEIN FOLDING;

ADENOSINE TRIPHOSPHATASE; CHAPERONE; HEAT SHOCK PROTEIN 60; OLIGOMER;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CONTROLLED STUDY; DEGENERATIVE DISEASE; DELETION MUTANT; ENTROPY; ENZYME ACTIVITY; GENE DELETION; IN VITRO STUDY; MITCHAP 60 DISEASE; MOUSE; MUTATIONAL ANALYSIS; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN FOLDING; PROTEIN FUNCTION; PROTEIN PURIFICATION; PROTEIN STABILITY;

AMINO ACID SEQUENCE; ANIMALS; CHAPERONIN 60; ENTROPY; HUMANS; MICE; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; MOLECULAR SEQUENCE DATA; NEURODEGENERATIVE DISEASES; POINT MUTATION; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

EID: 70350502104     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M109.031997     Document Type: Article

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