Neutrophil: Foe or friend?;Le neutrophile: Ennemi ou ami?

Medecine/Sciences

Volumn 25, Issue 8-9, 2009, Pages 699-704

  Dumas, Aline ^a   Pouliot, Marc ^a  

^a University Laval   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ADENOSINE A2A RECEPTOR; CHEMOKINE; CYTOKINE;

CELL FUNCTION; CELLULAR IMMUNITY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; HOST RESISTANCE; HUMAN; IMMUNOMODULATION; IMMUNOREGULATION; INTRACELLULAR SPACE; MULTINUCLEAR CELL; NEUTROPHIL; NONHUMAN; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

EID: 70350501685     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/2009258-9699     Document Type: Review

References (37)

1. Witko-Sarsat V, Rieu P, Descamps-Latscha B, et al. Neutrophils: molecules, functions and pathophysiological aspects. Lab Invest 2000 ; 80 : 617-653
2. Segal AW. How neutrophils kill microbes. Annu Rev Immunol 2005 ; 23 : 197-223.
3. Gougerot-Pocidalo MA, El Benna J, My-Chan Dang P, et al. Quand les polynucléaires neutrophiles attrapent les agents pathogènes dans leurs filets. Med Sci (Paris) 2007 ; 23 : 464-465 (Pubitemid 46826167)
4. Chakravarti A, Allaeys I, Poubelle PE. Neutrophile et immunité : est-ce inné ou acquis ? Med Sci (Paris) 2007 ; 23 : 862-867
5. Cassatella MA. The production of cytokines by polymorphonuclear neutrophils. Immunol Today 1995 ; 16 : 21-26
6. Cassatella MA. Neutrophil-derived proteins: selling cytokines by the pound. Adv Immunol 1999 ; 73 : 369-509.
7. Dinarello CA. Proinflammatory cytokines. Chest 2000 ; 118 : 503-508
8. O'Dell JR. Anticytokine therapy: a new era in the treatment of rheumatoid arthritis? N Engl J Med 1999 ; 340 : 310-312
9. Baggiolini M, Dewald B, Moser B. Interleukin-8 and related chemotactic cytokines - CXC and CC chemokines. Adv Immunol 1994 ; 55 : 97-179. (Pubitemid 124006545)
10. St-Onge M, Flamand N, Biarc J, et al. Characterization of prostaglandin E2 generation through the cyclooxygenase (COX)-2 pathway in human neutrophils. Biochim Biophys Acta 2007 ; 1771 : 1235-1245
11. Hicks A, Monkarsh SP, Hoffman AF, et al. Leukotriene B4 receptor antagonists as therapeutics for inflammatory disease: preclinical and clinical developments. Expert Opin Investig Drugs 2007 ; 16 : 1909-1920
12. Ham EA, Soderman DD, Zanetti ME, et al. Inhibition by prostaglandins of leukotriene B4 release from activated neutrophils. Proc Natl Acad Sci USA 1983 ; 80 : 4349-4353
13. Oh-ishi S, Utsunomiya I, Yamamoto T, et al. Effects of prostaglandins and cyclic AMP on cytokine production in rat leukocytes. Eur J Pharmacol 1996 ; 300 : 255-259 (Pubitemid 26144800)
14. Lawrence T, Gilroy DW. Chronic inflammation: a failure of resolution? Int J Exp Pathol 2007 ; 88 : 85-94.
15. Hurst SM, McLoughlin RM, Monslow J, et al. Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J Immunol 2002 ; 169 : 5244-5251 (Pubitemid 35217196)
16. Hurst SM, Wilkinson TS, McLoughlin RM, et al. Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity 2001 ; 14 : 705-714
17. Huynh ML, Fadok VA, Henson PM. Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation. J Clin Invest 2002 ; 109 : 41-50.
18. Bours MJ, Swennen EL, Di Virgilio F, et al. Adenosine 5′-triphosphate and adenosine as endogenous signaling molecules in immunity and inflammation. Pharmacol Ther 2006 ; 112 : 358-404. (Pubitemid 44486409)
19. Hasko G, Linden J, Cronstein B, et al. Adenosine receptors: therapeutic aspects for inflammatory and immune diseases. Nat Rev Drug Discov 2008 ; 7 : 759-770
20. Fortin A, Harbour D, Fernandes M, et al. Differential expression of adenosine receptors in human neutrophils: up-regulation by specific Th1 cytokines and lipopolysaccharide. J Leukoc Biol 2006 ; 79 : 574-585 (Pubitemid 44831234)
21. Ohta A, Sitkovsky M. Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage. Nature 2001 ; 414 : 916-920 (Pubitemid 34024743)
22. Cronstein BN, Naime D, Ostad E. The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation. J Clin Invest 1993 ; 92 : 2675-2682 (Pubitemid 24006532)
23. Cronstein BN, Rosenstein ED, Kramer SB, et al. Adenosine: a physiologic modulator of superoxide anion generation by human neutrophils. Adenosine acts via an A2 receptor on human neutrophils. J Immunol 1985 ; 135 : 1366-1371
24. Flamand N, Boudreault S, Picard S, et al. Adenosine, a potent natural suppressor of arachidonic acid release and leukotriene biosynthesis in human neutrophils. Am J Respir Crit Care Med 2000 ; 161 : S88-94.
25. Cadieux JS, Leclerc P, St-Onge M, et al. Potentiation of neutrophil cyclooxygenase-2 by adenosine: an early anti-inflammatory signal. J Cell Sci 2005 ; 118 : 1437-1447 (Pubitemid 40585124)
26. Pouliot M, Fiset ME, Masse M, et al. Adenosine up-regulates cyclooxygenase-2 in human granulocytes: impact on the balance of eicosanoid generation. J Immunol 2002 ; 169 : 5279-5286 (Pubitemid 35217200)
27. Surette ME, Krump E, Picard S, et al. Activation of leukotriene synthesis in human neutrophils by exogenous arachidonic acid: inhibition by adenosine A(2a) receptor agonists and crucial role of autocrine activation by leukotriene B(4). Mol Pharmacol 1999 ; 56 : 1055-1062
28. McColl SR, St-Onge M, Dussault AA, et al. Immunomodulatory impact of the A2A adenosine receptor on the profile of chemokines produced by neutrophils. Faseb J 2006 ; 20 : 187-189 (Pubitemid 43100509)
29. 2+ pathway. Circ Res 2006 ; 99 : 590-597 (Pubitemid 44401450)
30. Wahl AF, Wallace PM. Oncostatin M in the anti-inflammatory response. Ann Rheum Dis 2001 ; 60 (suppl 3) : 75-80.
31. Revan S, Montesinos MC, Naime D, et al. Adenosine A2 receptor occupancy regulates stimulated neutrophil function via activation of a serine/threonine protein phosphatase. J Biol Chem 1996 ; 271 : 17114-17118 (Pubitemid 26244260)
32. Flamand N, Surette ME, Picard S, et al. Cyclic AMP-mediated inhibition of 5-lipoxygenase translocation and leukotriene biosynthesis in human neutrophils. Mol Pharmacol 2002 ; 62 : 250-256 (Pubitemid 34804103)
33. Thibault N, Burelout C, Harbour D, et al. Occupancy of adenosine A2a receptors promotes fMLP-induced cyclic AMP accumulation in human neutrophils: impact on phospholipase D activity and recruitment of small GTPases to membranes. J Leukoc Biol 2002 ; 71 : 367-377
34. Lukashev D, Ohta A, Apasov S, et al. Cutting edge: physiologic attenuation of proinflammatory transcription by the Gs protein-coupled A2A adenosine receptor in vivo. J Immunol 2004 ; 173 : 21-24 (Pubitemid 38797321)
35. Schulte G, Fredholm BB. Signalling from adenosine receptors to mitogen-activated protein kinases. Cell Signal 2003 ; 15 : 813-827 (Pubitemid 36776656)
36. Pouliot M, Gilbert C, Borgeat P, et al. Expression and activity of prostaglandin endoperoxide synthase-2 in agonist-activated human neutrophils. Faseb J 1998 ; 12 : 1109-1123 (Pubitemid 28418941)
37. Pierce A, Legrand D, Mazurier J. La lactoferrine : une protéine multifonctionnelle. Med Sci (Paris) 2009 ; 25 : 361-369