-
1
-
-
0030048681
-
Results of long-term iron-chelating therapy
-
Gabutti V, Piga A. Results of long-term iron-chelating therapy. Acta Haematol. 95(1), 26-36 (1996).
-
(1996)
Acta Haematol.
, vol.95
, Issue.1
, pp. 26-36
-
-
Gabutti, V.1
Piga, A.2
-
2
-
-
0033536288
-
The β-thalassemias
-
Olivieri NF. The β-thalassemias. N. Engl. J. Med. 341(2), 99-109 (1999).
-
(1999)
N. Engl. J. Med.
, vol.341
, Issue.2
, pp. 99-109
-
-
Olivieri, N.F.1
-
3
-
-
0018614007
-
Iron absorption and loading in β-thalassemia intermedia
-
Pippard MJ, Warner GT, Callender ST, Weatherall DJ. Iron absorption and loading in β-thalassemia intermedia. Lancet 2(8147), 819-821 (1979).
-
(1979)
Lancet
, vol.2
, Issue.8147
, pp. 819-821
-
-
Pippard, M.J.1
Warner, G.T.2
Callender, S.T.3
Weatherall, D.J.4
-
4
-
-
32144431895
-
Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: A basis for clinical decision making
-
DOI 10.1200/JCO.2005.01.7038
-
Malcovati L, Porta MG, Pascutto C et al. Prognostic factors and life expectancy in myelodysplastic syndromes classified according to WHO criteria: a basis for clinical decision making. J. Clin. Oncol. 23(30), 7594-7603 (2005). (Pubitemid 46291823)
-
(2005)
Journal of Clinical Oncology
, vol.23
, Issue.30
, pp. 7594-7603
-
-
Malcovati, L.1
Della Porta, M.G.2
Pascutto, C.3
Invernizzi, R.4
Boni, M.5
Travaglino, E.6
Passamonti, F.7
Arcaini, L.8
Maffioli, M.9
Bernasconi, P.10
Lazzarino, M.11
Cazzola, M.12
-
5
-
-
34248383686
-
Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation
-
DOI 10.1182/blood-2006-10-054924
-
Armand P, Kim HT, Cutler CS et al. Prognostic impact of elevated pretransplantation serum ferritin in patients undergoing myeloablative stem cell transplantation. Blood 109(10), 4586-4588 (2007). (Pubitemid 46743431)
-
(2007)
Blood
, vol.109
, Issue.10
, pp. 4586-4588
-
-
Armand, P.1
Kim, H.T.2
Cutler, C.S.3
Ho, V.T.4
Koreth, J.5
Alyea, E.P.6
Soiffer, R.J.7
Antin, J.H.8
-
6
-
-
49149112388
-
Neither serum ferritin nor the number of red blood cell transfusions affect overall survival in refractory anemia with ringed sideroblasts
-
Chee CE, Steensma DP, Wu W, Hanson CA, Tefferi A. Neither serum ferritin nor the number of red blood cell transfusions affect overall survival in refractory anemia with ringed sideroblasts. Am. J. Hematol. 83(8), 611-613 (2008)
-
(2008)
Am. J. Hematol.
, vol.83
, Issue.8
, pp. 611-613
-
-
Chee, C.E.1
Steensma, D.P.2
Wu, W.3
Hanson, C.A.4
Tefferi, A.5
-
7
-
-
0037272767
-
Guidelines for the diagnosis and therapy of adult myelodysplastic syndromes
-
DOI 10.1046/j.1365-2141.2003.03907.x
-
Bowen D, Culligan D, Jowitt S et al. Guidelines for the diagnosis and therapy of adult myelodysplastic syndromes. Br. J. Haematol. 120(2), 187-200 (2003). (Pubitemid 36194166)
-
(2003)
British Journal of Haematology
, vol.120
, Issue.2
, pp. 187-200
-
-
Bowen, D.1
Culligan, D.2
Jowitt, S.3
Kelsey, S.4
Mufti, G.5
Oscier, D.6
Parker, J.7
-
8
-
-
55549139528
-
Consensus statement on iron overload in myelodysplastic syndromes
-
MDS Foundation's Working Group on Transfusional Iron Overload
-
Bennett JM. MDS Foundation's Working Group on Transfusional Iron Overload. Consensus statement on iron overload in myelodysplastic syndromes. Am. J. Hematol. 83(11), 858-861 (2008).
-
(2008)
Am. J. Hematol.
, vol.83
, Issue.11
, pp. 858-861
-
-
Bennett, J.M.1
-
9
-
-
66449133812
-
Design of an ongoing Phase I-II open label, dose escalation trial using the oral chelator deferasirox to treat iron overload in HFE-related hereditary hemochromatosis (HH)
-
Pietrangelo A, Brissot P, Bonkovsky H et al. Design of an ongoing Phase I-II open label, dose escalation trial using the oral chelator deferasirox to treat iron overload in HFE-related hereditary hemochromatosis (HH). Blood 109(11), 788a (2007).
-
(2007)
Blood
, vol.109
, Issue.11
-
-
Pietrangelo, A.1
Brissot, P.2
Bonkovsky, H.3
-
10
-
-
0034464884
-
Pharmacosurveillance and quality of care of thalassaemic patients. a large scale epidemiological survey
-
Italian Colaborative Group on Thalassaemia
-
Arboretti R, Tognoni G, Alberti D. Italian Colaborative Group on Thalassaemia. Pharmacosurveillance and quality of care of thalassaemic patients. A large scale epidemiological survey. Eur. J. Clin. Pharmacol. 56(12), 915-922 (2001).
-
(2001)
Eur. J. Clin. Pharmacol.
, vol.56
, Issue.12
, pp. 915-922
-
-
Arboretti, R.1
Tognoni, G.2
Alberti, D.3
-
11
-
-
0023555692
-
Management of iron overload in the pediatric patient
-
Cohen A. Management of iron overload in the pediatric patient. Hematol. Oncol. Clin. North Am. 1 (3), 521-544 (1987). (Pubitemid 18087564)
-
(1987)
Hematology/Oncology Clinics of North America
, vol.1
, Issue.3
, pp. 521-544
-
-
Cohen, A.1
-
12
-
-
34548721000
-
Clinical and economic burden of infused iron chelation therapy in the United States
-
Payne K, Desrosiers M, Caro J et al. Clinical and economic burden of infused iron chelation therapy in the United States. Transfusion 47(10), 1820-1829 (2007).
-
(2007)
Transfusion
, vol.47
, Issue.10
, pp. 1820-1829
-
-
Payne, K.1
Desrosiers, M.2
Caro, J.3
-
13
-
-
0038324389
-
Development of tridentate iron chelators: From desferrithiocin to ICL670
-
DOI 10.2174/0929867033457610
-
Nick H, Acklin P, Lattmann R et al. Development of tridentate iron chelators: From desferrithiocin to ICL670. Curr. Med. Chem. 10(12), 1065-1076 (2003). (Pubitemid 36582249)
-
(2003)
Current Medicinal Chemistry
, vol.10
, Issue.12
, pp. 1065-1076
-
-
Nick, H.1
Acklin, P.2
Lattmann, R.3
Buehlmayer, P.4
Hauffe, S.5
Schupp, J.6
Alberti, D.7
-
14
-
-
0037906104
-
Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to β-thalassemia
-
Galanello R, Piga A, Alberti D, Rouan MC, Bigler H, Séchaud R. Safety, tolerability, and pharmacokinetics of ICL670, a new orally active iron-chelating agent in patients with transfusion-dependent iron overload due to β-thalassemia. J. Clin. Pharmacol. 43(6), 565-572 (2003). (Pubitemid 36613115)
-
(2003)
Journal of Clinical Pharmacology
, vol.43
, Issue.6
, pp. 565-572
-
-
Galanello, R.1
Piga, A.2
Alberti, D.3
Rouan, M.-C.4
Bigler, H.5
Sechaud, R.6
-
15
-
-
33745774771
-
Randomized phase II trial of deferasirox (Exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload
-
Piga A, Galanello R, Forni GL et al. Randomized Phase II trial of deferasirox (exjade, ICL670), a once-daily, orally-administered iron chelator, in comparison to deferoxamine in thalassemia patients with transfusional iron overload. Haematologica 91(7), 873-880 (2006). (Pubitemid 44023139)
-
(2006)
Haematologica
, vol.91
, Issue.7
, pp. 873-880
-
-
Piga, A.1
Galanello, R.2
Forni, G.L.3
Cappellini, M.D.4
Origa, R.5
Zappu, A.6
Donato, G.7
Bordone, E.8
Lavagetto, A.9
Zanaboni, L.10
Sechaud, R.11
Hewson, N.12
Ford, J.M.13
Opitz, H.14
Albert, D.15
-
16
-
-
33646414765
-
A Phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with β-thalassemia
-
Landmark Phase III trial establishing efficacy and safety of deferasirox in patients with β-thalassemia
-
Cappellini MD, Cohen A, Piga A et al. A Phase 3 study of deferasirox (ICL670), a once-daily oral iron chelator, in patients with β-thalassemia. Blood 107(9), 3455-3462 (2006). • Landmark Phase III trial establishing efficacy and safety of deferasirox in patients with β-thalassemia.
-
(2006)
Blood
, vol.107
, Issue.9
, pp. 3455-3462
-
-
Cappellini, M.D.1
Cohen, A.2
Piga, A.3
-
17
-
-
33846012866
-
A randomised comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease
-
DOI 10.1111/j.1365-2141.2006.06455.x
-
Vichinsky E, Onyekwere O, Porter J et al. A randomized comparison of deferasirox versus deferoxamine for the treatment of transfusional iron overload in sickle cell disease. Br. J. Haematol. 136(3), 501-508 (2007). (Pubitemid 46046309)
-
(2007)
British Journal of Haematology
, vol.136
, Issue.3
, pp. 501-508
-
-
Vichinsky, E.1
Onyekwere, O.2
Porter, J.3
Swerdlow, P.4
Eckman, J.5
Lane, P.6
Files, B.7
Hassell, K.8
Kelly, P.9
Wilson, F.10
Bernaudin, F.11
Forni, G.L.12
Okpala, I.13
Ressayre-Djaffer, C.14
Alberti, D.15
Holland, J.16
Marks, P.17
Fung, E.18
Fischer, R.19
Mueller, B.U.20
Coates, T.21
more..
-
18
-
-
70449715018
-
Improved survival in patients with myelodysplastic syndrome receiving iron chelation therapy
-
Leitch H, Leger C, Goodman T et al. Improved survival in patients with myelodysplastic syndrome receiving iron chelation therapy. Clin. Leuk. 2(3), 205-211 (2008).
-
(2008)
Clin. Leuk.
, vol.2
, Issue.3
, pp. 205-211
-
-
Leitch, H.1
Leger, C.2
Goodman, T.3
-
19
-
-
60749134100
-
Deferasirox in MDS patients with transfusion-caused iron overload - A Phase-II study
-
Metzgeroth G, Dinter D, Schultheis B et al. Deferasirox in MDS patients with transfusion-caused iron overload - a Phase-II study. Ann. Hematol. 88(4), 301-310 (2008).
-
(2008)
Ann. Hematol.
, vol.88
, Issue.4
, pp. 301-310
-
-
Metzgeroth, G.1
Dinter, D.2
Schultheis, B.3
-
20
-
-
38049151217
-
Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): A 1-yr prospective study
-
Porter J, Galanello R, Saglio G et al. Relative response of patients with myelodysplastic syndromes and other transfusion-dependent anaemias to deferasirox (ICL670): a 1-yr prospective study. Eur. J. Haematol. 80(2), 168-176 (2008).
-
(2008)
Eur. J. Haematol.
, vol.80
, Issue.2
, pp. 168-176
-
-
Porter, J.1
Galanello, R.2
Saglio, G.3
-
21
-
-
70450127266
-
Efficacy and safety of deferasirox (Exjade® ) in patients with transfusion-dependent anemias: 1-year results from the large, prospective, multicenter EPIC study
-
American Society of Hematology 50th Annual Meeting abstracts
-
Cappellini M, El-Beshlawy A, Kattamis A et al. Efficacy and safety of deferasirox (Exjade® ) in patients with transfusion-dependent anemias: 1-year results from the large, prospective, multicenter EPIC study. American Society of Hematology 50th Annual Meeting abstracts. Blood 112(11), 1319 (2008).
-
(2008)
Blood
, vol.112
, Issue.11
, pp. 1319
-
-
Cappellini, M.1
El-Beshlawy, A.2
Kattamis, A.3
-
22
-
-
65449124273
-
Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: A systematic review and economic evaluation
-
ix-xi, 1-121
-
McLeod C, Fleeman N, Kirkham J et al. Deferasirox for the treatment of iron overload associated with regular blood transfusions (transfusional haemosiderosis) in patients suffering with chronic anaemia: a systematic review and economic evaluation. Health Technol. Assess. 13(1), iii-iv, ix-xi, 1-121 (2009).
-
(2009)
Health Technol. Assess.
, vol.13
, Issue.1
-
-
McLeod, C.1
Fleeman, N.2
Kirkham, J.3
-
23
-
-
33749988821
-
Once dailyoral deferasirox (Exjade®, ICL670) versus infusional deferoxamine as iron chelation therapy in patients with sickle-cell disease receiving frequent transfusions: A cost-effectiveness analysis
-
Delea TE, Thomas SK, Baldi JF, Coates TD. Once dailyoral deferasirox (Exjade® , ICL670) versus infusional deferoxamine as iron chelation therapy in patients with sickle-cell disease receiving frequent transfusions: a cost-effectiveness analysis. Blood 106, 5584 (2005).
-
(2005)
Blood
, vol.106
, pp. 5584
-
-
Delea, T.E.1
Thomas, S.K.2
Baldi, J.F.3
Coates, T.D.4
-
24
-
-
33845353462
-
Cost-effectiveness analysis of oral iron chelation therapy with deferasirox (Exjade®, ICL670) versus infusional chelation therapy with deferoxamine in patients with transfusion-dependent myelodysplastic syndrome
-
Delea TE, Thomas SK, Baladi JF, Phatak PD. Cost-effectiveness analysis of oral iron chelation therapy with deferasirox (Exjade® , ICL670) versus infusional chelation therapy with deferoxamine in patients with transfusion-dependent myelodysplastic syndrome. Blood 106, 5585 (2005).
-
(2005)
Blood
, vol.106
, pp. 5585
-
-
Delea, T.E.1
Thomas, S.K.2
Baladi, J.F.3
Phatak, P.D.4
-
25
-
-
65449182239
-
Cost of current iron chelation infusion therapy and cost effectiveness of once-daily oral deferasirox in transfusion-dependent thalassemia patients in Canada
-
Presented at
-
Delea TE, El Ouagari K, Sofrygin O. Cost of current iron chelation infusion therapy and cost effectiveness of once-daily oral deferasirox in transfusion-dependent thalassemia patients in Canada. Presented at: American Society of Hematology 48th Annual Meeting, FL, USA, 3349 (2006).
-
(2006)
American Society of Hematology 48th Annual Meeting, FL, USA
, pp. 3349
-
-
Delea, T.E.1
El Ouagari, K.2
Sofrygin, O.3
-
26
-
-
34247271478
-
Cost effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassaemia patients: US healthcare system perspective
-
DOI 10.2165/00019053-200725040-00005
-
Delea T, Sofrygin O, Thomas S, Baladi JF, Phatak P, Coates TD. Cost-effectiveness of once-daily oral chelation therapy with deferasirox versus infusional deferoxamine in transfusion-dependent thalassemia patients: US healthcare system perspective. Pharmacoeconomics 25, 329-342 (2007). • Most detailed cost-effectiveness analysis of deferasirox versus deferoxamine from a US healthcare system perspective. (Pubitemid 46607383)
-
(2007)
PharmacoEconomics
, vol.25
, Issue.4
, pp. 329-342
-
-
Delea, T.E.1
Sofrygin, O.2
Thomas, S.K.3
Baladi, J.-F.4
Phatak, P.D.5
Coates, T.D.6
-
28
-
-
70449720443
-
Cost-effectiveness of once-daily oral chelation therapy with deferasirox (Exjade® ) versus infusional deferoxamine in transfusion dependent thalassemic patients: A Brazilian perspective
-
Presented at
-
Calebro A, Delea TE, Sofrygin O et al. Cost-effectiveness of once-daily oral chelation therapy with deferasirox (Exjade® ) versus infusional deferoxamine in transfusion dependent thalassemic patients: a Brazilian perspective. Presented at: European Hematology Association 11th Annual Congress. Amsterdam, The Netherlands, 15-18 June 2006.
-
European Hematology Association 11th Annual Congress. Amsterdam, the Netherlands, 15-18 June 2006
-
-
Calebro, A.1
Delea, T.E.2
Sofrygin, O.3
-
30
-
-
70449705747
-
Cost utility analysis of deferasirox (Exjade® ) versus deferoxamine (Desferal) for patients requiring iron chelation therapy in the United Kingdom
-
Presented at
-
Karnon J, Akehurst R, Jewitt K, Ossa D. Cost utility analysis of deferasirox (Exjade® ) versus deferoxamine (Desferal) for patients requiring iron chelation therapy in the United Kingdom. Presented at: European Hematology Association 12th Annual Congress. Vienna, Austria, 7-10 June 2007.
-
European Hematology Association 12th Annual Congress. Vienna, Austria, 7-10 June 2007
-
-
Karnon, J.1
Akehurst, R.2
Jewitt, K.3
Ossa, D.4
-
31
-
-
46449131386
-
Cost-utility analysis of deferasirox compared to standard therapy with desferrioxamine for patients requiring iron chelation therapy in the United Kingdom
-
DOI 10.1185/03007990802077442
-
Karnon J, Tolley K, Oyee J, Jewitt K, Ossa D, Akehurst R. Cost utility analysis of deferasirox compared to standard therapy with desferrioxamine for patients requiring iron chelation therapy in the United Kingdom. Curr. Med. Res. Opin. 24(6), 1609-1621 (2008). (Pubitemid 351929059)
-
(2008)
Current Medical Research and Opinion
, vol.24
, Issue.6
, pp. 1609-1621
-
-
Karnon, J.1
Tolley, K.2
Oyee, J.3
Jewitt, K.4
Ossa, D.5
Akehurst, R.6
-
32
-
-
0027772390
-
Markov models in medical decision making: A practical guide
-
Sonnenberg FA, Beck JR. Markov models in medical decision making: a practical guide. Med. Decis. Making 13(4), 322-338 (1993).
-
(1993)
Med. Decis. Making
, vol.13
, Issue.4
, pp. 322-338
-
-
Sonnenberg, F.A.1
Beck, J.R.2
-
33
-
-
0037930751
-
Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with β-thalassaemia major: Application of SQUID biomagnetic liver susceptometry
-
DOI 10.1046/j.1365-2141.2003.04297.x
-
Fischer R, Longo F, Nielsen P, Engelhardt R, Hider RC, Piga A. Monitoring long-term efficacy of iron chelation therapy by deferiprone and desferrioxamine in patients with β-thalassaemia major: application of SQUID biomagnetic liver susceptometry. Br. J. Haematol. 121(6), 938-948 (2003). (Pubitemid 36760315)
-
(2003)
British Journal of Haematology
, vol.121
, Issue.6
, pp. 938-948
-
-
Fischer, R.1
Longo, F.2
Nielsen, P.3
Engelhardt, R.4
Hider, R.C.5
Piga, A.6
-
34
-
-
0041807885
-
What is the price of life and why doesn't it increase at the rate of inflation?
-
Ubel PA, Hirth RA, Chernew ME, Fendrick AM. What is the price of life and why doesn't it increase at the rate of inflation? Arch. Intern. Med. 163(14), 1637-1641 (2003).
-
(2003)
Arch. Intern. Med.
, vol.163
, Issue.14
, pp. 1637-1641
-
-
Ubel, P.A.1
Hirth, R.A.2
Chernew, M.E.3
Fendrick, A.M.4
-
35
-
-
0024310392
-
Desferrioxamine ototoxicity: Evaluation of risk factors in thalassaemic patients and guidelines for safe dosage
-
Porter JB, Jaswon MS, Huehns ER, East CA, Hazell JW. Desferrioxamine ototoxicity: evaluation of risk factors in thalassaemic patients and guidelines for safe dosage. Br. J. Haematol. 73(3), 403-409 (1989).
-
(1989)
Br. J. Haematol.
, vol.73
, Issue.3
, pp. 403-409
-
-
Porter, J.B.1
Jaswon, M.S.2
Huehns, E.R.3
East, C.A.4
Hazell, J.W.5
-
37
-
-
70449697789
-
-
Ferriprox® International Website (Accessed May 2009)
-
Ferriprox® International Website www.ferriprox.com/worldwide/default. asp (Accessed May 2009)
-
-
-
-
38
-
-
34547464547
-
-
Novartis Pharmaceuticals Corporation. East Hanover, New Jersey 07936 Rev: October (Accessed December 2008)
-
Full prescribing information Exjade®. Novartis Pharmaceuticals Corporation. East Hanover, New Jersey 07936 Rev: October 2008 www.pharma.us.novartis.com/product/pi/ pdf/exjade.pdf (Accessed December 2008)
-
(2008)
Full Prescribing Information Exjade®
-
-
|