Antibodies determine virulence in Dengue

Annals of the New York Academy of Sciences

Volumn 1171, Issue SUPPL. 1, 2009, Pages

  Halstead, Scott B ^a  

^a Pediatric Dengue Vaccine Initiative   (United States)

Author keywords

antibodies; dengue viruses (DENV); virulence

Indexed keywords

ANTIBODY; ENVELOPE PROTEIN; FC RECEPTOR; VIRUS ANTIBODY;

ANTIGENICITY; BLOOD VESSEL PERMEABILITY; DENGUE; DENGUE SHOCK SYNDROME; DENGUE VIRUS; DENGUE VIRUS 1; DENGUE VIRUS 2; DENGUE VIRUS 3; DENGUE VIRUS 4; DOWN REGULATION; GENOTYPE; HUMAN; HYPOVOLEMIA; INNATE IMMUNITY; MACROPHAGE; MONOCYTE; NONHUMAN; PROTEIN DOMAIN; REVIEW; VIRUS CONCENTRATION; VIRUS NEUTRALIZATION; VIRUS STRAIN; VIRUS VIRULENCE; ARTICLE; BLOOD; CLASSIFICATION; IMMUNOLOGY; PATHOGENICITY; PATHOPHYSIOLOGY; VIRULENCE;

DENGUE VIRUS GROUP;

ANTIBODIES, VIRAL; DENGUE; DENGUE HEMORRHAGIC FEVER; DENGUE VIRUS; HUMANS; HYPOVOLEMIA; VIRULENCE;

EID: 70350452043     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05052.x     Document Type: Review

References (71)

1. Rosen, L. 1986. Dengue in Greece in 1927 and 1928 and the pathogenesis of dengue hemorrhagic fever: new data and a different conclusion. Am. J. Trop. Med. Hyg. 35: 642-653.
2. Halstead, S.B. & G. Papaevangelou. 1980. Transmission of dengue 1 and 2 viruses in Greece in 1928. Am. J. Trop. Med. Hyg. 29: 635-637.
3. Hammon, W.M., A. Rudnick & G.E. Sather. 1960. Viruses associated with epidemic hemorrhagic fevers of the Philippines and Thailand. Science 131: 1102-1103.
4. Hammon, W.M. & G.E. Sather. 1964. Virological findings in the 1960 hemorrhagic fever epidemic (dengue) in Thailand. Am. J. Trop. Med. Hyg. 13: 629-641.
5. Barnes, W.J.S. & L. Rosen. 1974. Fatal hemorrhagic disease and shock associated with primary dengue infection on a Pacific island. Am. J. Trop. Med. Hyg. 23: 495-506.
6. Scott, R.M., S. Nimmannitya, W.H. Bancroft & P. Mansuwan. 1976. Shock syndrome in primary dengue infections. Am. J. Trop. Med. Hyg. 25: 866-874.
7. Vaughn,D.W., S.Green, S.Kalayanarooj, et al. 2000. Dengue viremia titer, antibody response pattern, and virus serotype correlate with disease severity. J. Infect. Dis. 181: 2-9.
8. Watts, D.M., K.R. Porter, P. Putvatana, et al. 1999. Failure of secondary infection with American genotype dengue 2 to cause dengue haemorrhagic fever [see comments]. Lancet 354: 1431-1434.
9. White, N.J. 1999. Variation in virulence of dengue virus [comment]. Lancet 354: 1401-1402.
10. Guzman, M.G., G.P. Kouri, J. Bravo, et al. 1990. Dengue hemorrhagic fever in Cuba, 1981: a retrospective seroepidemiologic study. Am. J. Trop. Med. Hyg. 42: 179-184.
11. Leitmeyer, K.C., D.W. Vaughn, D.M. Watts, et al. 1999. Dengue virus structural differences that correlate with pathogenesis. J. Virol. 73: 4738-4747.
12. Rico-Hesse, R. 2003. Microevolution and virulence of dengue viruses. Adv. Virus. Res. 59: 315-341.
13. Armstrong, P.M. & R. Rico-Hesse. 2001. Differential susceptibility of Aedes aegypti to infection by the American and Southeast Asian genotypes of dengue type 2 virus. Vector. Borne. Zoonotic. Dis. 1: 159-168.
14. Armstrong, P.M. & R. Rico-Hesse. 2003. Efficiency of dengue serotype 2 virus strains to infect and disseminate in Aedes aegypti. Am. J. Trop.Med.Hyg. 68: 539-544.
15. Anderson, J.R. & R. Rico-Hesse. 2006. Aedes aegypti vectorial capacity is determined by the infecting genotype of dengue virus. Am. J. Trop.Med. Hyg. 75: 886-892.
16. Pryor, M.J., J.M. Carr, H. Hocking, et al. 2001.Replication of dengue virus type 2 in human monocytederived macrophages: comparisons of isolates and recombinant viruses with substitutions at amino acid 390 in the envelope glycoprotein. Am. J. Trop. Med. Hyg. 65: 427-434.
17. Cologna,R. & R. Rico-Hesse. 2003. American genotypestructures decrease dengue virus output from human monocytes and dendritic cells. J. Virol. 77: 3929-3938.
18. Duangchanda, S., M. Tanaka, K. Morita, et al. 1994. Comparative nucleotide and deduced amino acid sequence of the envelope glycoprotein gene among three dengue virus type 2 strains isolated from patients with different disease severities in Maha Sarakham, northeast Thailand. Southeast Asian J. Trop. Med. Public Health 25: 243-251.
19. Thant, K.Z., K. Morita, A. Igarashi. 1995. Sequences of E/NS1 gene junction from four dengue- 2 viruses of Northeastern Thailand and their evolutionary relationships with other dengue-2 viruses. Microbiol. Immunol. 39: 581-590.
20. Thant, K.Z., K. Morita & A. Igarashi. 1996. Detection of the disease severity-related molecular differences among new Thai dengue-2 isolates in 1993, based on their structural proteins and major nonstructural protein NS1 sequences. Microbiol. Immunol. 40: 205-216.
21. Rico-Hesse, R., L.M. Harrison, A. Nisalak, et al. 1998. Molecular evolution of dengue type 2 virus in Thailand. Am. J. Trop. Med. Hyg. 58: 96-101.
22. Raekiansyah,M., A. Pramesyanti, B. Bela, et al. 2005. Genetic variations and relationship among dengue virus type 3 strains isolated from patients with mild or severe form of dengue disease in Indonesia and Thailand. Southeast Asian. J. Trop. Med. Public Health 36: 1187-1197.
23. Pandey, B.D. & A. Igarashi. 2000. Severity-related molecular differences among nineteen strains of dengue type 2 viruses. Microbiol Immunol 44: 179-188.
24. Pandey, B.D., K. Morita, F. Hasebe, et al. 2000. Molecular evolution, distribution and genetic relationship among the dengue 2 viruses isolated frm different clinical severity. Southeast Asian J. Trop. Med. Public Health 31: 266-272.
25. Mangada, M.N. & A. Igarashi. 1997. Sequences of terminal non-coding regions from four dengue- 2 viruses isolated from patients exhibiting different disease severities. Virus. Genes 14: 5-12.
26. Zhou, Y., M.P. Mammen Jr., C. Klungthong, et al. 2006. Comparative analysis reveals no consistent association between the secondary structure of the 3- untranslated region of dengue viruses and disease syndrome. J. Gen. Virol. 87(Pt 9): 2595-2603.
27. Simmons, J.S., J.H. St John & F.H.K. Reynolds 1931. Experimental studies of dengue. The Philippine Journal of Science 44: 1-252.
28. Halstead, S.B. 1974. Etiologies of the experimental dengues of Siler and Simmons. Am. J. Trop. Med. Hyg. 23: 974-982.
29. Nishiura, H. & S.B. Halstead. 2007. Natural history of dengue virus (DEN)-1 and DEN-4 infections. Reanalysis of classical studies. J. Infect. Dis. 195: 1007-1013.
30. Gubler, D.J. 1997. Dengue and dengue hemorrhagic fever: its history and resurgence as a global public health problem. In Dengue andDengueHemorrhagic Fever. D.J. Gubler & G. Kuno, Eds.: 1-22. CAB International. New York.
31. Hotta, S. 1953. Dengue epidemics in Japan, 1942- 1945. J. Trop. Med. Hyg. 56: 83-89.
32. Sabin, A.B. 1952. Research on dengue duringWorld War II. Am. J. Trop. Med. Hyg. 1: 30-50.
33. Hotta, S. 1952. Experimental studies in dengue I. Isolation, identification andmodification of the virus. J. Infect. Dis. 90: 1-9.
34. PAHO. 1978. Dengue in the Caribbean, 1977. Montego Bay, Jamaica. 1-186. Published Proceedings by PAHO.
35. Mas, P. 1977. Dengue fever in Cuba in: Some Laboratory aspects. Dengue in the Caribbean, 1977 1978. Montego Bay, Jamaica. 1-186. Published Proceedings by PAHO.
36. Liu, H.W., T.L. Ho, C.S. Hwang & Y.H. Liao 1989. Clinical observations of virologically confirmed dengue fever in the 1987 outbreak in southern Taiwan. Kao-Hsiung I Hsueh Ko Hsueh Tsa Chih (Kaohsiung Journal of Medical Sciences) 5: 42-49.
37. Effler, P.V., L. Pang, P. Kitsutani, et al. 2005. Dengue fever, Hawaii, 2001-2002. Emerg. Infect. Dis. 11: 742-749.
38. Sabin, A.B. 1952. Dengue. In Viral and Rickettsial Infections of Man, 2nd ed. T.M. Rivers, Ed.: 556-568. J.B. Lippincott Company. Philadelphia.
39. Kuberski, T., L. Rosen, D. Reed & J. Mataika. 1977. Clinical and Laboratory observations on patients with primary and secondary dengue type 1 infections with hemorrhagic manifestations in Fiji. Am. J. Trop. Med. Hyg. 26: 775-783.
40. Nimmannitya, S., S.B. Halstead, S. Cohen & M.R. Margiotta. 1969. Dengue and chikungunya virus infection in man in Thailand, 1962-1964. I. Observations on hospitalized patients with hemorrhagic fever. Am. J. Trop. Med. Hyg. 18: 954-971.
41. Tsai, C.J., C.H.Kuo, P.C. Chen & C.S. Changcheng. 1991. Upper gastrointestinal bleeding in dengue fever. Am. J. Gastroenterol. 86: 33-35.
42. Guzman, M.G., G. Kouri, L. Valdes, et al. 2000. Epidemiologic studies on dengue in Santiago de Cuba, 1997. Am. J. Epidemiol. 152: 793-799.
43. Kouri, G.P., M.G. Guzman, J.R. Bravo & C. Triana. 1989. Dengue haemorrhagic fever/dengue shock syndrome: lessons from the Cuban epidemic, 1981. Bull. World Health Organ. 67: 375-380.
44. Schlesinger, R.W., I. Gordon, J.W. Frankel, et al. 1956. Clinical and serologic response of man to immunization with attenuated dengue and yellow fever viruses. J. Immunol. 77: 352-364.
45. Hammon, W.M. 1969. Observations on dengue fever, benign protector and killer: a Dr Jekyll and Mr Hyde. Am. J. Trop. Med. Hyg. 18: 159-165.
46. Seet, R.C.S., E. Ooi, H.B.Wong & N.I. Paton. 2005. An outbreak of primary dengue infection among migrant Chinese workers in Singapore characterized by prominent gastrointestinal symptoms and a high proportion of symptomatic cases. J. Clin. Virol. 33: 336-340.
47. Gubler, D.J., D. Reed, L. Rosen & J.C. Hitchcock Jr. 1978. Epidemiological, clinical,and virologic observations on dengue in The Kingdom of Tonga. Am. J. Trop. Med. Hyg. 27: 581-589.
48. Chandler, A.G. & L.Rice. 1923. Observations on the etiology of dengue fever.Am. J. Trop.Med. 3: 233-262.
49. Rice, L. 1923. A clinical report of the Galveston epidemic of 1922. Am. J. Trop. Med. 3: 73-90.
50. Gubler, D.J.,W. Suharyono, I. Lubis, et al. 1979. Epidemic dengue hemorrhagic fever in rural Indonesia. I.Virological and epidemiological studies. Am. J. Trop. Med. Hyg. 28: 701-710.
51. Buchy, P., V.L. Vo, T.X. Trinh, et al. 2005. Secondary dengue virus type 4 infections in Vietnam. Southeast Asian J. Trop. Med. Public Health 36: 178-185.
52. Nisalak, A., T.P. Endy, S. Nimmannitya, et al. 2003. Serotype-specific dengue virus circulation and dengue disease in Bangkok, Thailand from 1973 to 1999. Am. J. Trop. Med. Hyg. 68: 191-202.
53. Gibbons, R.V., S. Kalanarooj, R.G. Jarman, et al. 2007. Analysis of repeat hospital admissions for dengue to estimate the frequency of third or fourth dengue infections resulting in admissions and dengue hemorrhagic fever, and serotype sequences. Am. J. Trop. Med. Hyg. 77: 910-913.
54. Kochel, T.J., D.M. Watts, S.B. Halstead, et al. 2002. Effect of dengue-1 antibodies on American dengue-2 viral infection and dengue haemorrhagic fever. Lancet 360: 310-312.
55. Kochel, T.J., D.M. Watts, A.S. Gozalo, et al. 2005. Cross-serotype neutralization of dengue virus in Aotus nancymae monkeys. J. Infect. Dis. 191: 1000-1004.
56. Halstead, S.B. 2003. Neutralization and antibody dependent enhancement of dengue viruses. Adv. Virus Res. 60: 421-467.
57. Halstead, S.B. 2007. Dengue. Lancet 370: 1644-1652.
58. Halstead, S.B. 2008. Pathogenesis: risk factors prior to infection. In Dengue. S.B. Halstead, Ed.: 219-256. Imperial College Press. London.
59. Guzman, M.G., G. Kouri & S.B. Halstead. 2000. Do escape mutants explain rapid increases in dengue case-fatality rates within epidemics? Lancet 355: 1902-1903.
60. Jessie, K., M.Y. Fong, S.Devi, et al. 2004. Localization of dengue virus in naturally infected human tissues, by immunohistochemistry and in site hybridization. J. Infect. Dis. 189: 1411-1418.
61. Durbin, A.P., M.J. Vargas, K. Wanionek, et al. 2008. Phenotyping of peripheral blood mononuclear cells during acute dengue illness demonstrates infection and increased activation of monocytes in severe cases compared to classic dengue fever. Virology 376: 29-435.
62. Shresta, S., K.L. Sharar, D.M. Prigozhin, et al. 2006. Murine model for dengue virus-induced lethal disease with increased vascular permeability. J. Virol. 80: 10208-10217.
63. Kyle, J.L., S.J. Balsitis, L. Zhang, et al. 2008. Antibodies play a greater role than immune cells in heterologous protection against secondary dengue virus infection in a mouse model. Virology 380: 296-303.
64. Goncalvez, A.P., R. Men, C. Wernly, et al. 2004. Chimpanzee Fab fragments and a derived humanized immunoglobulin G1 anibody that efficiently cross-neutralizes dengue types 1 and type 2 viruses. J. Virol. 78: 12910-12918.
65. Goncalvez, A.P., R.E. Engle, M. St. Claire, et al. 2007. Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention. Proc. Natl. Acad. Sci. USA 104: 9422-9427.
66. Pierson, T.C., D.H. Fremont, R.J. Kuhn & M.S. Diamond. 2008. Structural insights into the mechanisms of antibody-mediated neutralization of flavivirus infection: implications for vaccine development. Cell. Host. Microbe 4: 229-238.
67. Mehlhop, E. &M.S. Diamond. 2008. Themolecular basis of antibody protection against West Nile virus. Curr. Top. Microbiol. Immunol 317: 125-153.
68. Mahalingam, S. & B.A. Lidbury. 2002. Suppression of lipopolysaccharide-induced antiviral transcription factor (STAT-1 and NF-kB) complexes by antibody-dependent enhancement of macrophage infection by Ross River virus. PNAS 99: 13819-13824.
69. Chareonsirisuthigul, T., S. Kalayanarooj & S. Ubol. 2007. Dengue virus (DENV) antibody-dependent enhancement of infection upregulates the production of anti-inflammatory cytokines, but suppresses anti-DENV free radical and pro-inflammatory cytokine production, in THP-1 cells. J. Gen. Virol. 88(Pt 2): 365-375.
70. Ubol, S., P.Masrinoul, J. Chaijaruwanich, et al. 2008. Differences in global gene expression in peripheral blood mononuclear cells indicate a significant role of the innate responses in progression of dengue fever but not dengue hemorrhagic fever. J. Infect. Dis. 197: 1459-1467.
71. Simmons, C.P., S. Popper, C. Dolocek, et al. 2007. Patterns of host genome-wide gene transcript abundance in the peripheral blood of patients with acute dengue hemorrhagic fever. J. Infect. Dis. 195: 1097-1107.