Zinc finger transcription factor ecotropic viral integration site 1 is induced by all-trans retinoic acid (ATRA) and acts as a dual modulator of the ATRA response

FEBS Journal

Volumn 276, Issue 22, 2009, Pages 6810-6822

  Bingemann, Sonja C ^a   Konrad, Torsten A ^a   Wieser, Rotraud ^a  

^a MEDICAL UNIVERSITY OF VIENNA   (Austria)

Author keywords

All trans retinoic acid; EVI1; Feedback inhibition; RARE; Transcription regulation

Indexed keywords

ECOTROPIC VIRAL INTEGRATION SITE 1; RETINOIC ACID; UNCLASSIFIED DRUG;

ARTICLE; ECOTROPIC VIRUS; FEEDBACK SYSTEM; GENE EXPRESSION; GENE REPRESSION; GENETIC TRANSCRIPTION; NONHUMAN; PRIORITY JOURNAL; VIRUS DNA CELL DNA INTERACTION;

CELL LINE, TUMOR; CHROMATIN IMMUNOPRECIPITATION; DNA-BINDING PROTEINS; EXONS; GENE EXPRESSION REGULATION; HUMANS; NEOPLASM PROTEINS; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENES; RECEPTORS, RETINOIC ACID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTORS; TRETINOIN;

MAMMALIA;

EID: 70350439262     PISSN: 1742464X     EISSN: 17424658     Source Type: Journal    
DOI: 10.1111/j.1742-4658.2009.07398.x     Document Type: Article

References (48)

1. Wieser R (2007) The oncogene and developmental regulator EVI1: expression, biochemical properties, and biological functions. Gene 396, 346 357.
2. Hoyt P, Bartholomew C, Davis A, Yutzey K, Gamer L, Potter S, Ihle J Mucenski M (1997) The Evi1 proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development. Mech Dev 65, 55 70.
3. Soderholm J, Kobayashi H, Mathieu C, Rowley J Nucifora G (1997) The leukemia-associated gene MDS1/EVI1 is a new type of GATA-binding transactivator. Leukemia 11, 352 358.
4. Chakraborty S, Senyuk V, Sitailo S, Chi Y Nucifora G (2001) Interaction of EVI1 with CBP and P/CAF results in reversible acetylation of EVI1 and in colocalization in nuclear speckles. J Biol Chem 276, 44936 44943.
5. Izutsu K, Kurokawa M, Imai Y, Maki K, Mitani K Hirai H (2001) The corepressor CtBP interacts with Evi-1 to repress transforming growth factor beta signaling. Blood 97, 2815 2822.
6. Vinatzer U, Taplick J, Seiser C, Fonatsch C Wieser R (2001) The leukaemia-associated transcription factors EVI-1 and MDS1/EVI1 repress transcription and interact with histone deacetylase. Br J Haematol 114, 566 573.
7. Yuasa H, Oike Y, Iwama A, Nishikata I, Sugiyama D, Perkins A, Mucenski M, Suda T Morishita K (2005) Oncogenic transcription factor Evi1 regulates hematopoietic stem cell proliferation through GATA-2 expression. EMBO J 24, 1976 1987.
8. Yatsula B, Lin S, Read A, Poholek A, Yates K, Yue D, Hui P Perkins A (2005) Identification of binding sites of EVI1 in mammalian cells. J Biol Chem 280, 30712 30722.
9. Kurokawa M, Mitani K, Irie K, Matsuyama T, Takahashi T, Chiba S, Yazaki Y, Matsumoto K Hirai H (1998) The oncoprotein Evi-1 represses TGF-beta signalling by inhibiting Smad3. Nature 394, 92 96.
10. Buonamici S, Li D, Mikhail F, Sassano A, Platanias L, Colamonici O, Anastasi J Nucifora G (2005) EVI1 abrogates interferon-alpha response by selectively blocking PML induction. J Biol Chem 280, 428 436.
11. Laricchia-Robbio L, Fazzina R, Li D, Rinaldi C, Sinha K, Chakraborty S Nucifora G (2006) Point mutations in two EVI1 Zn fingers abolish EVI1-GATA1 interaction and allow erythroid differentiation of murine bone marrow cells. Mol Cell Biol 26, 7658 7666.
12. Senyuk V, Sinha K, Li D, Rinaldi C, Yanamandra S Nucifora G (2007) Repression of RUNX1 activity by EVI1: a new role of EVI1 in leukemogenesis. Cancer Res 67, 5658 5666.
13. Vinatzer U, Mannhalter C, Mitterbauer M, Gruener H, Greinix H, Schmidt H, Fonatsch C Wieser R (2003) Quantitative comparison of the expression of EVI1 and its presumptive antagonist, MDS1/EVI1, in patients with myeloid leukemia. Genes Chromosomes Cancer 36, 80 89.
14. Aytekin M, Vinatzer U, Musteanu M, Raynaud S Wieser R (2005) Regulation of the expression of the oncogene EVI1 through the use of alternative mRNA 5'-ends. Gene 356, 160 168.
15. Haas K, Kundi M, Sperr W, Esterbauer H, Ludwig W, Ratei R, Koller E, Gruener H, Sauerland C, Fonatsch C et al. (2008) Expression and prognostic significance of different mRNA 5′-end variants of the oncogene EVI1 in 266 patients with de novo AML: EVI1 and MDS1/EVI1 overexpression both predict short remission duration. Genes Chromosomes Cancer 47, 288 298.
16. Fears S, Mathieu C, Zeleznik Le N, Huang S, Rowley J Nucifora G (1996) Intergenic splicing of MDS1 and EVI1 occurs in normal tissues as well as in myeloid leukemia and produces a new member of the PR domain family. Proc Natl Acad Sci USA 93, 1642 1647.
17. Wimmer K, Vinatzer U, Zwirn P, Fonatsch C Wieser R (1998) Comparative expression analysis of the antagonistic transcription factors EVI1 and MDS1-EVI1 in murine tissues and during in vitro hematopoietic differentiation. Biochem Biophys Res Commun 252, 691 696.
18. Sitailo S, Sood R, Barton K Nucifora C (1999) Forced expression of the leukemia-associated gene EVI1 in ES cells: a model for myeloid leukemia with 3q26 rearrangements. Leukemia 13, 1639 1645.
19. Sood R, Talwar TrikhaA, Chakrabarti S Nucifora G (1999) MDS1/EVI1 enhances TGF-beta 1 signaling and strengthens its growth-inhibitory effect, but the leukemia-associated fusion protein AML1/MDS1/EVI1, product of the t(3;21), abrogates growth-inhibition in response to TGF-beta 1. Leukemia 13, 348 357.
20. Cuenco G Ren R (2004) Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice. Oncogene 23, 569 579.
21. Perkins A, Mercer J, Jenkins N Copeland N (1991) Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development. Development 111, 479 487.
22. Kazama H, Kodera T, Shimizu S, Mizoguchi H Morishita K (1999) Ecotropic viral integration site-1 is activated during, and is sufficient for, neuroectodermal P19 cell differentiation. Cell Growth Differ 10, 565 573.
23. Xi Z, Russell M, Woodward S, Thompson F, Wagner L Taetle R (1997) Expression of the Zn finger gene, EVI-1, in acute promyelocytic leukemia. Leukemia 11, 212 220.
24. Niederreither K, Subbarayan V, Dolle P Chambon P (1999) Embryonic retinoic acid synthesis is essential for early mouse post-implantation development. Nat Genet 21, 444 448.
25. McCaffery P, Adams J, Maden M Rosa-Molinar E (2003) Too much of a good thing: retinoic acid as an endogenous regulator of neural differentiation and exogenous teratogen. Eur J Neurosci 18, 457 472.
26. Bastien J Rochette-Egly C (2004) Nuclear retinoid receptors and the transcription of retinoid-target genes. Gene 328, 1 16.
27. McGrane M (2007) Vitamin A regulation of gene expression: molecular mechanism of a prototype gene. J Nutr Biochem 18, 497 508.
28. Balmer J Blomhoff R (2002) Gene expression regulation by retinoic acid. J Lipid Res 43, 1773 1808.
29. Bordereaux D, Fichelson S, Tambourin P Gisselbrecht S (1990) Alternative splicing of the Evi-1 zinc finger gene generates mRNAs which differ by the number of zinc finger motifs. Oncogene 5, 925 927.
30. de The H, Vivanco-Ruiz M, Tiollais P, Stunnenberg H Dejean A (1990) Identification of a retinoic acid responsive element in the retinoic acid receptor beta gene. Nature 343, 177 180.
31. Palmer S, Brouillet J, Kilbey A, Fulton R, Walker M, Crossley M Bartholomew C (2001) Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins. J Biol Chem 276, 25834 25840.
32. Konrad T, Karger A, Hackl H, Schwarzinger I, Herbacek I Wieser R (2009) Inducible expression of EVI1 in human myeloid cells causes phenotypes consistent with its role in myelodysplastic syndromes. J Leukoc Biol 86, 813 822.
33. Van Campenhout C, Nichane M, Antoniou A, Pendeville H, Bronchain O, Marine J, Mazabraud A, Voz M Bellefroid E (2006) Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation. Dev Biol 294, 203 219.
34. Brooks D, Woodward S, Thompson F, Dos Santos B, Russell M, Yang J, Gua X, Trent J, Alberts D Taetle R (1996) Expression of the zinc finger gene EVI-1 in ovarian and other cancers. Br J Cancer 74, 1518 1525.
35. Poppe B, Dastugue N, Vandesompele J, Cauwelier B, De Smet B, Yigit N, De Paepe A, Cervera J, Recher C, De Mas V et al. (2006) EVI1 is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements. Genes Chromosomes Cancer 45, 349 356.
36. Lugthart S, van Drunen E, van Norden Y, van Hoven A, Erpelinck C, Valk P, Beverloo H, Lowenberg B Delwel R (2008) High EVI1 levels predict adverse outcome in acute myeloid leukemia: prevalence of EVI1 overexpression and chromosome 3q26 abnormalities underestimated. Blood 111, 4329 4337.
37. Bartholomew C, Kilbey A, Clark A Walker M (1997) The Evi-1 proto-oncogene encodes a transcriptional repressor activity associated with transformation. Oncogene 14, 569 577.
38. Kilbey A Bartholomew C (1998) Evi-1 ZF1 DNA binding activity and a second distinct transcriptional repressor region are both required for optimal transformation of Rat1 fibroblasts. Oncogene 16, 2287 2291.
39. Cattaneo F Nucifora G (2008) EVI1 recruits the histone methyltransferase SUV39H1 for transcription repression. J Cell Biochem 105, 344 352.
40. Spensberger D Delwel R (2008) A novel interaction between the proto-oncogene Evi1 and histone methyltransferases, SUV39H1 and G9a. FEBS Lett 582, 2761 2767.
41. Tanaka T, Nishida J, Mitani K, Ogawa S, Yazaki Y Hirai H (1994) Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation with dependence on the second zinc finger domain. J Biol Chem 269, 24020 24026.
42. Sato T, Goyama S, Nitta E, Takeshita M, Yoshimi M, Nakagawa M, Kawazu M, Ichikawa M Kurokawa M (2008) Evi-1 promotes para-aortic splanchnopleural hematopoiesis through up-regulation of GATA-2 and repression of TGF-b signaling. Cancer Sci 99, 1407 1413.
43. Grimwade D, Walker H, Oliver F, Wheatley K, Harrison C, Harrison G, Rees J, Hann I, Stevens R, Burnett A et al. (1998) The importance of diagnostic cytogenetics on outcome in AML: analysis of 1,612 patients entered into the MRC AML 10 trial. The Medical Research Council Adult and Children's Leukaemia Working Parties. Blood 92, 2322 2333.
44. Boer J, Bonten-Surtel J Grosveld G (1998) Overexpression of the nucleoporin CAN/NUP214 induces growth arrest, nucleocytoplasmic transport defects, and apoptosis. Mol Cell Biol 18, 1236 1247.
45. Livak K Schmittgen T (2001) Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. Methods 25, 402 408.
46. Jiang S, Wu M, Chen L, Hung M, Lin H, Chang G Chang T (2005) Identification and characterization of the retinoic acid response elements in the human RIG1 gene promoter. Biochem Biophys Res Commun 331, 630 639.
47. Fischer-Fantuzzi L Vesco C (1988) Cell-dependent efficiency of reiterated nuclear signals in a mutant simian virus 40 oncoprotein targeted to the nucleus. Mol Cell Biol 8, 5495 5503.
48. Lee H, Park U, Kim E Um S (2007) MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation. EMBO J 26, 3545 3557.