Ecotropic viral integration site-1 is activated during, and is sufficient for, neuroectodermal P19 cell differentiation

Cell Growth and Differentiation

Volumn 10, Issue 8, 1999, Pages 565-573

  Kazama, Hiroshi ^a,b   Kodera, Takao ^a   Shimizu, Seiichi ^a   Mizoguchi, Hideaki ^b   Morishita, Kazuhiro ^a  

^a NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DIMETHYL SULFOXIDE; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN 2; RETINOIC ACID;

ANIMAL CELL; ARTICLE; ASTROCYTE; CANCER CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; EMBRYO DEVELOPMENT; GENE EXPRESSION; GENE INDUCTION; GENE OVEREXPRESSION; IN SITU HYBRIDIZATION; MESODERM; MONOLAYER CULTURE; MOUSE; NEURAL CREST; NEUROECTODERM; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTO ONCOGENE; VIRUS DNA CELL DNA INTERACTION;

ANIMALS; ANTIGENS, DIFFERENTIATION; ASTROCYTES; BLOTTING, NORTHERN; BLOTTING, WESTERN; CELL AGGREGATION; CELL DIFFERENTIATION; CELL DIVISION; CLONE CELLS; DNA-BINDING PROTEINS; FLUORESCENT ANTIBODY TECHNIQUE; GENE EXPRESSION; MICE; MICROTUBULE-ASSOCIATED PROTEINS; NERVOUS SYSTEM; NEURAL CREST; PROTO-ONCOGENES; RNA, MESSENGER; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRETINOIN; TUMOR CELLS, CULTURED;

EID: 0032792654     PISSN: 10449523     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (39)

1. Mucenski, M. L., Taylor, B. A., Ihle, J. N., Hartley, J. W., Morse, H. C., Jenkins, N. A., and Copeland, N. G. Identification of a common ecotropic viral integration site, Evi-1, in the DNA of AKXD murine myeloid tumors. Mol. Cell. Biol., 8: 301-308, 1988.
2. Morishita, K., Parker, D. S., Mucenski, M. L., Jenkins, N. A., Copeland N. G., and Ihle, J. N. Retroviral activation of a novel gene encoding a zinc finger protein in IL-3-dependent myeloid leukemia cell lines. Cell, 54: 831-840, 1988.
3. Morishita, K., Parganas, E., Willman, C. L., Whittaker, M. H., Drabkin, H., Oval, J., Taetle, R., and Ihle, J. N. Activation of Evi-1 gene expression in human acute myelogenous leukemias by rearrangements spanning 300-400 kb in chromosome 3q26. Proc. Natl. Acad. Sci. USA, 89: 3937-3941, 1992.
4. Ausubel, F. M., Brent, R., Kingston, R. E., Moore, D. D., Seidman, J. G., Smith, J. A., and Struhl, K. Current Protocols in Molecular Biology. New York: Greene Publishing Associates and Weiley Interscience; 1992.
5. Mitani, K., Ogawa, S., Tanaka, T., Miyoshi, H., Kurokawa, M., Mano, H., Yazaki, Y., Ohki, M., and Hirai, H. Generation of the AML1-EVI-1 fusion gene in the t(3;21)(q26;q22) causes blastic crisis in chronic myelocytic leukemia. EMBO J., 13: 504-510, 1994.
6. Nucifora, G., Begy, C. R., Kobayashi, H., Roulston, D., Claxton, D., Pedersen-Bjergaard, J., Paraganas, E., Ihle, J. N., and Rowley, J. D. Consistent intergenic splicing and production of multiple transcripts between AML1 at 21q22 and unrelated genes at 3q26 in (3;21)(q26;q22) translocations. Proc. Natl. Acad. Sci. USA, 91: 4004-4008, 1994.
7. Peeters, P., Wlodarska, I., Baens, M., Criel, A., Selleslag, D., Hagemeijer, A., Van den Berghe, H., and Marynen, P. Fusion of ETV6 to MDS1/EVI1 as a result of t(3;12)(q26;p13) in myeloproliferative disorders. Cancer Res., 57: 564-569, 1997.
8. Delwel, R., Funabiki, T., Kreider, B. L., Morishita, K., and Ihle, J. N. Four of the seven zinc fingers of the Evi-1 myeloid transforming gene are required for sequence-specific binding to GA(C/T)AAGA(T/C)AAGATAA. Mol. Cell. Biol., 13: 4291-4300, 1993.
9. Funabiki, T., Kreider, B. L., and Ihle, J. N. The carboxyl domain of zinc fingers of the Evi-1 myeloid transforming gene binds a consensus sequence of GAAGATGAG. Oncogene, 9: 1575-1581, 1994.
10. Morishita, K., Suzukawa, K., Taki, T., Ihle, J. N., and Yokota, J. EVI-1 zinc finger protein works as a transcriptional activator via binding to a consensus sequence of GACAAGATAAGATAA N 1-28 CTCATCTTC. Oncogene, 10: 1961-1967, 1995.
11. Tanaka, T., Nishida, J., Mitani, K., Ogawa, S., Yazaki, Y., and Hirai, H. Evi-1 raises AP-1 activity and stimulates c-fos promoter transactivation with dependence on the second zinc finger domain. J. Biol. Chem., 269: 24020-24026, 1994.
12. Tanaka, T., Mitani, K., Kurokawa, M., Ogawa, S., Tanaka, K., Nishida, J., Yazaki, Y., Shibata, Y., and Hirai, H. Dual functions of the AML1/Evi-1 chimeric protein in the mechanism of leukemogenesis in t(3;21) leukemias. Mol. Cell. Biol., 15: 2383-2392, 1995.
13. Kreider, B. L., Orkin, S. H., and Ihle, J. N. Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene. Proc. Natl. Acad. Sci. USA, 90: 6454-6458, 1993.
14. Morishita, K., Parganas, E., Matsugi, T., and Ihle, J. N. Expression of the Evi-1 zinc finger gene in 32Dc13 myeloid cells blocks granulocytic differentiation in response to granulocyte colony-stimulating factor. Mol. Cell. Biol., 12: 183-189, 1992.
15. Morishita, K., Parganas, E., Douglass, E. C., and Ihle, J. N. The Evi-1 zinc finger myeloid transforming gene is normally expressed in the kidney and in developing oocytes. Oncogene, 5: 963-971, 1990.
16. Perkins, A. S., Mercer, J. A., Jenkins, N. A., and Copeland, N. G. Patterns of Evi-1 expression in embryonic and adult tissues suggest that Evi-1 plays an important regulatory role in mouse development. Development (Camb.), 111: 479-487, 1991.
17. Hoyt, P. R., Bartholomew, C., Davis, A. J., Yulzey, K., Garner, L. W., Potter, S. S., Ihle, J. N., and Mucenski, M. L. The Evil proto-oncogene is required at midgestation for neural, heart, and paraxial mesenchyme development. Mech. Dev., 65: 55-70, 1997.
18. Garriga, G., Guenther, C., and Horvitz, H. R. Migrations of the Caenorhabditis elegans HSNs are regulated by egl-43, a gene encoding two zinc finger proteins. Genes Dev., 7: 2097-2019, 1993.
19. McBurney, M. W., Jones-Villeneuve, E. M. V., Edwards, M. K. S., and Anderson, P. J. Control of muscle and neural differentiation in a cultured embryonal carcinoma cell line. Nature (Lond.), 284: 353-355, 1982.
20. Dinsmore, J. H., and Solomon, F. Inhibition of MAP2 expression affects both morphological and cell division phenotypes of neural differentiation. Cell, 64: 817-826, 1991.
21. Bouillet, P., Oulad-Abdelghani, M., Vicaire, S., Gamier, J. M, Schuhbaur, B., Dolle, P., and Chambon, P. Efficient cloning of cDNAs retinoic acid-responsive genes in P19 embryonal carcinoma cells and characterization of a novel mouse gene, Stra1 (Mouse LERK-2/Eplg2). Dev. Biol., 170: 420-433, 1995.
22. Mizushima, S., and Nagata, S. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res., 18: 5322, 1990.
23. Mummery, C. L., Feijen, A., Van der Saag, P. T., Van der Brink, C. E., and De Laat, S. W. Clonal variants of differentiated P19 EC cells exhibit EGF receptor kinase activity. Dev. Biol., 109: 402-410, 1985.
24. Boudjelal, M., Taneja, R., Matsubara, S., Bouiltet, P., Dolle, P., and Chambon, P. Overexpression of Stra13, a novel retinoic acid-inducible gene of the basic helix-loop-helix family, inhibits mesodermal and promotes neural differentiation of P19 cells. Genes Dev., 11: 2052-2065, 1997.
25. Johnson, J. E., Zimmerman, K., Saito, T., and Anderson, D. J. Induction and repression of mammalian achaete-scute homologue (MASH) gene expression during neural differentiation of P19 embryonal carcinoma cells. Development (Camb.), 114: 75-87, 1992.
26. Salvatore, A. M., Cozzolino, M., Gargano, N., Galanti, S., Levi, A., and Alema, S. Neural differentiation of P19 embryonal cells exhibits cell-specific regulation of neurotrophin receptors. Neuroreport, 6: 873-877, 1995.
27. Lee, J. E., Hollenberg, S. M., Snider, L., Turner, D. L., Lipnick, N., and Weintraub, H. Conversion of Xenopus ectoderm into neurons by NeuroD, a basic helix-loop-helix protein. Science (Washington DC), 268: 836-844, 1995.
28. Ma, Q., Kintner, C., and Anderson, D. J. Identification of neurogenin, a vertebrate neural determination gene. Cell, 87: 43-52, 1996.
29. Cau, E., Gradwohl, G., Fode, C., and Guillemot, F. Mash1 activates a cascade of bHLH regulators in olfactory neuron progenitors. Development (Camb.), 124: 1611-1621, 1997.
30. De Groot, R. P., Kruyt, F. A. E., van der Saag, P. T., and Kruijer, W. Ecotropic expression of c-jun leads to differentiation of P19 embryonal carcinoma cells. EMBO J., 9: 1831-1937, 1990.
31. Hilberg, F., Aguzzi, A., Howells, N., and Wagner, E. F. c-jun is essential for normal mouse development and hepatogenesis. Nature (Lond.), 365: 179-181, 1993.
32. Johnson, R., van Lingen, S. B., Papaianoou, V. E., and Spiegelman, B. M. A null mutation at the c-jun locus causes embryonic lethality and retarded cell growth in culture. Genes Dev., 7: 1309-1317, 1993.
33. Chambon, P. A. Decade of molecular biology of retinoic acid receptors. FASEB J., 10: 940-954, 1996.
34. Kitabayashi, I., Eckner, R., Arany, Z., Chiu, R., Gachelin, G., Livingston, D. M., and Yokoyama, K. Phosphorylation of the adenovirus E1A-associated 300 kDa protein in response to retinoic acid and E1A during the differentiation of F9 cells. EMBO J., 14: 3496-3509, 1995.
35. Rudnicki, M. A., and McBumey, M. W. In: E. J. Robertson (ed.), Teratocarcinomas and Embryonic Stem Cells: A Practical Approach. Oxford: IRL Press, 1987.
36. Morishita, K., Parganas, E., Parham, D. M., Matsugi, T., and Ihle, J. N. Unique expression of the human Evi-1 gene in an endometrial carcinoma cell line: sequence of cDNA structure of alternatively spliced transcripts. Oncogene, 5: 1419-1423, 1990.
37. Sambrook, J, Fritsch, E. F., and Maniatis, T., Molecular Cloning: A Laboratory Manual. Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press, 1989.
38. Suzukawa, K., Parganas, E., Gajjar, A., Abe, T., Takahashi, S., Tani, K., Asano, S., Asou, H., Kamada, N., Yokota, J., Morishita, K., and Ihle, J. N. Identification of a breakpoint cluster region 3′ of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI-1 gene in acute myelogenous leukemias with inv(3)(q21q26). Blood, 64: 2681-2688, 1994.
39. Matsugi, T., Morishita, K., and Ihle, J. N. Identification, nuclear localization, and DNA-binding activity of the zinc finger protein encoded by the Evi-1 myeloid transforming gene. Mol. Cell. Biol., 10: 1259-1264, 1990.