Invasive tubular carcinoma of the breast frequently is clonally related to flat epithelial atypia and low-grade ductal carcinoma in situ

American Journal of Surgical Pathology

Volumn 33, Issue 11, 2009, Pages 1646-1653

  Aulmann, Sebastian ^a   Elsawaf, Zeinab ^a   Penzel, Roland ^a   Schirmacher, Peter ^a   Sinn, Hans Peter ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Breast cancer; DCIS; Flat epithelial atypia; Lobular neoplasia; Tubular carcinoma

Indexed keywords

MITOCHONDRIAL DNA;

ADULT; AGED; ARTICLE; BREAST CARCINOMA; CELL DAMAGE; CHROMOSOME 11Q; CHROMOSOME 16; CHROMOSOME 1P; CHROMOSOME 3P; CHROMOSOME 8P; CHROMOSOME ARM; CLINICAL ARTICLE; CONTROLLED STUDY; DNA SEQUENCE; HETEROZYGOSITY LOSS; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRADUCTAL CARCINOMA; NUCLEOTIDE SEQUENCE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, INTRADUCTAL, NONINFILTRATING; CARCINOMA, LOBULAR; CLONE CELLS; DNA MUTATIONAL ANALYSIS; DNA, MITOCHONDRIAL; DNA, NEOPLASM; EPITHELIAL CELLS; FEMALE; HUMANS; LOSS OF HETEROZYGOSITY; MIDDLE AGED; NEOPLASMS, MULTIPLE PRIMARY; TUMOR MARKERS, BIOLOGICAL;

EID: 70350439211     PISSN: 01475185     EISSN: 15320979     Source Type: Journal    
DOI: 10.1097/PAS.0b013e3181adfdcf     Document Type: Article

References (28)

1. Abdel-Fatah TM, Powe DG, Hodi Z, et al. High frequency of coexistence of columnar cell lesions, lobular neoplasia, and low grade ductal carcinoma in situ with invasive tubular carcinoma and invasive lobular carcinoma. Am J Surg Pathol. 2007;31:417-426.
2. Abdel-Fatah TM, Powe DG, Hodi Z, et al. Morphologic and molecular evolutionary pathways of low nuclear grade invasive breast cancers and their putative precursor lesions: further evidence to support the concept of low nuclear grade breast neoplasia family. Am J Surg Pathol. 2008;32:513-523.
3. Anderson S, Bankier AT, Barrel BG, et al. Sequence and organization of the human mitochondrial genome. Nature. 1981; 290:457-465.
4. Arpino G, Laucirica R, Elledge RM. Premalignant and in situ breast disease: biology and clinical implications. Ann Intern Med. 2005; 143:446-457.
5. Aulmann S, Elsawaf Z, Penzel R, et al. Clonal association of flat epithelial atypia and tubular breast cancer (Article in German). Pathologe. 2008;29(suppl 2):353-356.
6. Aulmann S, Penzel R, Longerich T, et al. Clonality of lobular carcinoma in situ (LCIS) and metachronous invasive breast cancer. Breast Cancer Res Treat. 2008;107:331-335.
7. Aulmann S, Schleibaum J, Penzel R, et al. Gains of chromosome region 3q26 in intraepithelial neoplasia and invasive squamous cell carcinoma of the vulva are frequent and independent of HPV status. J Clin Pathol. 2008;61:1034-1037.
8. Azzopardi JG. Problems in Breast Pathology. Philadelphia, PA: WB Saunders; 1979:192-213.
9. Chenna R, Sugawara H, Koike T, et al. Multiple sequence alignment with the Clustal series of programs. Nucleic Acids Res. 2003;31:3497-3500.
10. Clamp M, Cuff J, Searle SM, et al. The jalview java alignment editor. Bioinformatics. 2004;20:426-427.
11. Cook MG, Rohan TE. The patho-epidemiology of benign proliferative epithelial disorders of the female breast. J Pathol. 1985; 146:1-15.
12. Dabbs DJ, Carter G, Fudge M, et al. Molecular alterations in columnar cell lesions of the breast. Mod Pathol. 2006;19:344-349.
13. Fraser JL, Raza S, Chorny K, et al. Columnar alteration with prominent apical snouts and secretions: a spectrum of changes frequently present in breast biopsies performed for microcalcifica-tions. Am J Surg Pathol. 1998;22:1521-1527.
14. Goldstein NS, O'Malley BA. Cancerization of small ectatic ducts of the breast by ductal carcinoma in situ cells with apocrine snouts: a lesions associated with tubular carcinoma. Am J Clin Pathol. 1997; 107:561-566.
15. Goldstein NS, Bassi D, Watts JC, et al. E-cadherin reactivity of 95 noninvasive ductal and lobular lesions of the breast. Implications for the interpretation of problematic lesions. Am J Clin Pathol. 2001; 115:534-542.
16. Gunther K, Merkelbach-Bruse S, Amo-Takyi BK, et al. Differences in genetic alterations between primary lobular and ductal breast cancers detected by comparative genomic hybridization. J Pathol. 2001;193:40-47.
17. Hwang ES, Nyante SJ, Yi Chen Y, et al. Clonality of lobular carcinoma in situ and synchronous invasive lobular carcinoma. Cancer. 2004;100:2562-2572.
18. Leibl S, Regitnig P, Moinfar F. Flat epithelial atypia (DIN 1a, atypical columnar change): an underdiagnosed entity very frequently coexisting with lobular neoplasia. Histopathology. 2007; 50:859-865.
19. Moinfar F, Man YG, Bratthauer GL, et al. Genetic abnormalities in mammary ductal intraepithelial neoplasia-flat type (''clinging ductal carcinoma in situ''). Cancer. 2000;88:2072-2081.
20. Morandi L, Marucci G, Foschini MP, et al. Genetic similarities and differences between lobular in situ neoplasia (LN) and invasive lobular carcinoma of the breast. Virchows Arch. 2006;449: 14-23.
21. O'Malley FP, Mohsin SK, Badve S, et al. Interobserver reprodu-cibility in the diagnosis of flat epithelial atypia of the breast. Mod Pathol. 2006;19:172-179.
22. Page DL, Jensen RA, Simpson JF, et al. Historical and epidemio-logic background of human premalignant breast disease. J Mammary Gland Biol Neoplasia. 2000;5:341-349.
23. Rosen PP. Columnar cell hyperplasia is associated with lobular carcinoma in situ and tubular carcinoma. Am J Surg Pathol. 1999;23:1561.
24. Sahoo S, Recant WM. Triad of columnar cell alteration, lobular carcinoma in situ, and tubular carcinoma of the breast. Breast J. 2005;11:140-142.
25. Schnitt SJ. The diagnosis and management of pre-invasive breast disease: flat epithelial atypia-classification, pathologic features and clinical significance. Breast Cancer Res. 2003;5:263-268.
26. Schnitt SJ, Vincent-Salomon A. Columnar cell lesions of the breast. Adv Anat Pathol. 2003;10:113-124.
27. Simpson PT, Gale T, Reis-Filho JS, et al. Columnar cell lesions of the breast: the missing link in breast cancer progression? Am J Surg Pathol. 2005;29:734-746.
28. Sinn HP. Breast cancer precursors: lessons learned from molecular genetics. J Mol Med. 2009;87:113-115