Ranolazine antagonizes the effects of increased late sodium current on intracellular calcium cycling in rat isolated intact heart

Journal of Pharmacology and Experimental Therapeutics

Volumn 331, Issue 2, 2009, Pages 382-391

  Wasserstrom, J Andrew ^a   Sharma, Rohan ^a   O'Toole, Matthew J ^a   Zheng, Jiabo ^a   Kelly, James E ^a   Shryock, John ^b   Belardinelli, Luiz ^b   Aistrup, Gary L ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b GILEAD SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; ESTER DERIVATIVE; FLUO 4 ACETOXYMETHYLESTER; RANOLAZINE; TOXIN; UNCLASSIFIED DRUG;

ANEMONE; ANIMAL EXPERIMENT; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DRUG EFFECT; DRUG EXPOSURE; ELECTROCARDIOGRAM; HEART BEAT; HEART CONTRACTION; HEART MUSCLE POTENTIAL; HEART PACING; HEART REPOLARIZATION; ISOLATED HEART; LASER MICROSCOPY; NONHUMAN; PRIORITY JOURNAL; RAT; SODIUM CURRENT;

ACETANILIDES; ALGORITHMS; ANIMALS; CALCIUM; CALCIUM SIGNALING; CARDIAC PACING, ARTIFICIAL; CNIDARIAN VENOMS; ELECTRIC STIMULATION; ELECTROPHYSIOLOGY; ENZYME INHIBITORS; FEMALE; HEART; MALE; MICROSCOPY, CONFOCAL; MYOCARDIUM; NEUROTOXINS; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; SODIUM CHANNELS;

EID: 70350438424     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.109.156471     Document Type: Article

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