Synthetic organisms and living machines: Positioning the products of synthetic biology at the borderline between living and non-living matter

Systems and Synthetic Biology

Volumn 3, Issue 1, 2009, Pages 55-63

  Deplazes, Anna ^a   Huppenbauer, Markus ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Ethics; Life; Machines; Organisms; Philosophy; Synthetic biology; Synthetic life

Indexed keywords

EID: 70350398853     PISSN: 18725325     EISSN: 18725333     Source Type: Journal    
DOI: 10.1007/s11693-009-9029-4     Document Type: Article

References (18)

1. Andrianantoandro E, Basu S, Karig DK, Weiss R (2006) Synthetic biology: new engineering rules for an emerging discipline. Mol Syst Biol 2:1-14.
2. Bedau MA (2003) Artificial life: organization, adaptation and complexity from the bottom up. Trends Cogn Sci 7:505-512.
3. Brooks RA (2001) Steps towards living machines. In: Gomi T (ed) Evolutionary robotics from intelligent robotics to artificial life. Springer, Berlin, pp 72-93.
4. Deplazes A (2009) Synthetic biology-piecing a puzzle together. EMBO Rep (forthcoming).
5. Endy D (2005) Foundations for engineering biology. Nature 438:449-453.
6. Freitas RA Jr (2005) What is nanomedicine? Nanomedicine 1:2-9.
7. Gibson DG, Benders GA, Andrews-Pfannkoch C, Denisova EA, Baden-Tillson J, Zaveri H, Stockwell TB, Brownley A, Thomas DW, Algire MA, Merryman C, Young L, Noskov VN, Glass JI, Venter JC, Hutchison CA III, Smith HO (2008) Complete chemical synthesis, assembly, and cloning of a Mycoplasma genitalium genome. Science (New York, N.Y.) 319:1215-1220.
8. Glass JI, Assad-Garcia N, Alperovich N, Yooseph S, Lewis MR, Maruf M, Hutchison CA III, Smith HO, Venter JC (2006) Essential genes of a minimal bacterium. Proc Natl Acad Sci USA 103:425-430.
9. Hornby AS (1995) Oxford advanced learner's dictionary. Oxford University Press, Oxford.
10. Lartigue C, Glass JI, Alperovich N, Pieper R, Parmar PP, Hutchison CA III, Smith HO, Venter JC (2007) Genome transplantation in bacteria: changing one species to another. Science (New York, N.Y.) 317:632-638.
11. Luisi PL (2003) Autopoiesis: a review and a reappraisal. Die Naturwissenschaften 90:49-59.
12. Luisi PL (2006) The emergence of life, from chemical origins to synthetic biology. Cambridge University Press, Cambridge.
13. O'Neill J (2003) The varieties of intrinsic value. In: Light A, Rolston H III (eds) Environmental ethics. Blackwell Publishing, Malden, pp 131-142.
14. Pohorille A, Deamer D (2002) Artificial cells: prospects for biotechnology. Trends Biotechnol 20:123-128.
15. Rasmussen S, Bedau MA, Chen L, Deamer D, Krakauer DC, Packard NH, Stadler PF (2009) Introduction. In: Rasmussen S, Bedau MA, Chen L, Deamer D, Krakauer DC, Packard NH, Stadler PF (eds) Protocells, bridging nonliving and living matter. The MIT Press, Cambridge.
16. Riskin J (2007) Introduction: the Sistine gap. In: Riskin J (ed) Genesis redux, essays in the history and philosophy of artificial life. University of Chicago Press, Chicago, pp 1-34.
17. Sole RV, Munteanu A, Rodriguez-Caso C, Macia J (2007) Synthetic protocell biology: from reproduction to computation. Philos Trans R Soc Lond 362:1727-1739.
18. Szostak JW, Bartel DP, Luisi PL (2001) Synthesizing life. Nature 409:387-390.