-
1
-
-
34648828532
-
AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
-
Hardie,D.G. 2007. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat. Rev. Mol. Cell. Biol. 8: 774-785.
-
(2007)
Nat. Rev. Mol. Cell. Biol.
, vol.8
, pp. 774-785
-
-
Hardied, G.1
-
2
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
Kahn, B.B. et al. 2005. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab. 1: 15-25.
-
(2005)
Cell Metab.
, vol.1
, pp. 15-25
-
-
Kahn, B.B.1
-
3
-
-
33745215480
-
AMP-activated protein kinase and the regulation of Ca2+ signalling in O2-sensing cells
-
Evans, A.M. 2006. AMP-activated protein kinase and the regulation of Ca2+ signalling in O2-sensing cells. J. Physiol. 574: 113-123.
-
(2006)
J. Physiol.
, vol.574
, pp. 113-123
-
-
Evans, A.M.1
-
4
-
-
0035542970
-
AMP-activated protein kinase: The energy charge hypothesis revisited
-
Hardie, D.G. & S.A. Hawley. 2001. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23: 1112-1119.
-
(2001)
Bioessays
, vol.23
, pp. 1112-1119
-
-
Hardie, D.G.1
Hawley, S.A.2
-
5
-
-
0345107247
-
Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMPactivated protein kinase cascade
-
Hawley, S.A. et al. 2003. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMPactivated protein kinase cascade. J. Biol. 2: 28.
-
(2003)
J. Biol.
, vol.2
, pp. 28
-
-
Hawley, S.A.1
-
6
-
-
85047691317
-
CBS domains form energysensing modules whose binding of adenosine ligands is disrupted by disease mutations
-
Scott, J.W. et al. 2004. CBS domains form energysensing modules whose binding of adenosine ligands is disrupted by disease mutations. J. Clin. Invest. 113: 274-284.
-
(2004)
J. Clin. Invest.
, vol.113
, pp. 274-284
-
-
Scott, J.W.1
-
7
-
-
34848840368
-
Structural basis for AMP binding to mammalian AMP-activated protein kinase
-
Xiao, B. et al. 2007. Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature 449: 496-500.
-
(2007)
Nature
, vol.449
, pp. 496-500
-
-
Xiao, B.1
-
8
-
-
0029561919
-
5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC
-
Davies, S.P. et al. 1995. 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC. FEBS Lett. 377: 421-425.
-
(1995)
FEBS Lett.
, vol.377
, pp. 421-425
-
-
Davies, S.P.1
-
9
-
-
33845949733
-
Dissecting the role of 5--AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase
-
Suter, M. et al. 2006. Dissecting the role of 5--AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. J. Biol. Chem. 281: 32207-32216.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 32207-32216
-
-
Suter, M.1
-
10
-
-
67149111580
-
Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing
-
Dzeja, P. & A. Terzic. 2009. Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. Int. J. Mol. Sci. 10: 1729-1772.
-
(2009)
Int. J. Mol. Sci.
, vol.10
, pp. 1729-1772
-
-
Dzeja, P.1
Terzic., A.2
-
11
-
-
23044432463
-
Calmodulin-dependent protein kinase, kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
-
Hawley, S.A. et al. 2005. Calmodulin-dependent protein kinase, kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2: 9-19.
-
(2005)
Cell Metab.
, vol.2
, pp. 9-19
-
-
Hawley, S.A.1
-
12
-
-
57849090443
-
The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor
-
McBride, A. et al. 2009. The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor. Cell Metab. 9: 23-34.
-
(2009)
Cell Metab.
, vol.9
, pp. 23-34
-
-
McBride, A.1
-
13
-
-
0032529139
-
AMP-activated protein kinase: Greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform
-
Salt, I. et al. 1998. AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. Biochem. J. 334(Pt 1): 177-187.
-
(1998)
Biochem. J.
, vol.334
, Issue.PART. 1
, pp. 177-187
-
-
Salt, I.1
-
14
-
-
33744541891
-
Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres
-
Gregor, M. et al. 2006. Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres. J. Cell. Sci. 119: 1864-1875.
-
(2006)
J. Cell. Sci.
, vol.119
, pp. 1864-1875
-
-
Gregor, M.1
-
15
-
-
0031849916
-
Evidence for 5′ AMPactivated protein kinase mediation of the effect of muscle contraction on glucose transport
-
Hayashi, T. et al. 1998. Evidence for 5- AMPactivated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47: 1369-1373.
-
(1998)
Diabetes
, vol.47
, pp. 1369-1373
-
-
Hayashi, T.1
-
16
-
-
0033820422
-
5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes
-
Salt, I.P., J.M. Connell & G.W. Gould. 2000. 5-aminoimidazole-4- carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes 49: 1649-1656.
-
(2000)
Diabetes
, vol.49
, pp. 1649-1656
-
-
Salt, I.P.1
Connell, J.M.2
Gould, G.W.3
-
17
-
-
0016812869
-
Loss of chemoreceptive properties of the rabbit carotid body after destruction of the glomus cells
-
Verna, A., M. Roumy & L.M. Leitner. 1975. Loss of chemoreceptive properties of the rabbit carotid body after destruction of the glomus cells. Brain Res. 100: 13-23.
-
(1975)
Brain Res
, vol.100
, pp. 13-23
-
-
Verna, A.1
Roumy, M.2
Leitner, L.M.3
-
18
-
-
0034890091
-
Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle
-
Dipp, M., P.C. Nye & A.M. Evans. 2001. Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle. Am. J. Physiol. Lung Cell Mol. Physiol. 281: L318-L325.
-
(2001)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.281
-
-
Dipp, M.1
Nye, P.C.2
Evans, A.M.3
-
19
-
-
0031956106
-
Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin
-
Gaine, S.P.,M.A. Hales & N.A. Flavahan. 1998. Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin. Am. J. Physiol. 274: L657-L664.
-
(1998)
Am. J. Physiol.
, vol.274
-
-
Gaine, S.P.1
Hales, M.A.2
Flavahan, N.A.3
-
20
-
-
0027327956
-
Oxygen sensing in airway chemoreceptors
-
Youngson, C. et al. 1993. Oxygen sensing in airway chemoreceptors. Nature 365: 153-155.
-
(1993)
Nature
, vol.365
, pp. 153-155
-
-
Youngson, C.1
-
21
-
-
0031028005
-
Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells
-
Thompson, R.J., A. Jackson & C.A. Nurse. 1997. Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells. J. Physiol. 498(Pt 2): 503-510.
-
(1997)
J. Physiol.
, vol.498
, Issue.PART 2
, pp. 503-510
-
-
Thompson, R.J.1
Jackson, A.2
Nurse, C.A.3
-
22
-
-
0025959327
-
Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture
-
Stea, A. & C.A. Nurse. 1991. Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture. Pflugers Arch. 418: 93-101.
-
(1991)
Pflugers Arch
, vol.418
, pp. 93-101
-
-
Stea, A.1
Nurse, C.A.2
-
23
-
-
0026767130
-
Relative mitochondrial membrane potential and [Ca2+]i in type i cells isolated from the rabbit carotid body
-
Duchen, M.R. & T.J. Biscoe. 1992. Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body. J. Physiol. 450: 33-61.
-
(1992)
J. Physiol.
, vol.450
, pp. 33-61
-
-
Duchen, M.R.1
Biscoe, T.J.2
-
24
-
-
0026703693
-
Mitochondrial function in type i cells isolated from rabbit arterial chemoreceptors
-
Duchen, M.R. & T.J. Biscoe. 1992. Mitochondrial function in type I cells isolated from rabbit arterial chemoreceptors. J. Physiol. 450: 13-31.
-
(1992)
J. Physiol.
, vol.450
, pp. 13-31
-
-
Duchen, M.R.1
Biscoe, T.J.2
-
25
-
-
0029953806
-
Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery
-
Shigemori,K. et al. 1996. Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery. Am. J. Physiol. 270: L803-L809.
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Shigemori, K.1
-
26
-
-
41949089941
-
Functional mitochondria are required forO2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells
-
Buttigieg, J. et al. 2008. Functional mitochondria are required forO2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells. Am. J. Physiol. Cell Physiol. 294: C945-C956.
-
(2008)
Am. J. Physiol. Cell Physiol.
, vol.294
-
-
Buttigieg, J.1
-
27
-
-
0032052209
-
Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase
-
Gnaiger, E. et al. 1998. Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase. J. Exp. Biol. 201: 1129-1139.
-
(1998)
J. Exp. Biol.
, vol.201
, pp. 1129-1139
-
-
Gnaiger, E.1
-
28
-
-
0028053910
-
Carotid body chemoreceptors: From natural stimuli to sensory discharges
-
Gonzalez, C. et al. 1994. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74: 829-898.
-
(1994)
Physiol. Rev.
, vol.74
, pp. 829-898
-
-
Gonzalez, C.1
-
29
-
-
0019378297
-
Cat carotid body: Oxygen consumption and other parameters
-
Whalen, W.J. et al. 1981. Cat carotid body: oxygen consumption and other parameters. J. Appl. Physiol. 50: 129-133.
-
(1981)
J. Appl. Physiol.
, vol.50
, pp. 129-133
-
-
Whalen, W.J.1
-
30
-
-
9144224900
-
Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs
-
Weissmann, N. et al. 2003. Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs. Am. J. Respir. Cell. Mol. Biol. 29: 721-732.
-
(2003)
Am. J. Respir. Cell. Mol. Biol.
, vol.29
, pp. 721-732
-
-
Weissmann, N.1
-
31
-
-
37349041710
-
Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease
-
Hardie, D.G. 2008. Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease. FEBS Lett. 582: 81-89.
-
(2008)
FEBS Lett.
, vol.582
, pp. 81-89
-
-
Hardie, D.G.1
-
32
-
-
28844433635
-
The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
-
Shaw, R.J. et al. 2005. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310: 1642-1646.
-
(2005)
Science
, vol.310
, pp. 1642-1646
-
-
Shaw, R.J.1
-
33
-
-
0025865055
-
Energy state and vasomotor tone in hypoxic pig lungs
-
Buescher, P.C. et al. 1991. Energy state and vasomotor tone in hypoxic pig lungs. J. Appl. Physiol. 70: 1874-1881.
-
(1991)
J. Appl. Physiol.
, vol.70
, pp. 1874-1881
-
-
Buescher, P.C.1
-
34
-
-
29244463866
-
Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?
-
Evans, A.M. et al. 2005. Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? J. Biol. Chem. 280: 41504-41511.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 41504-41511
-
-
Evans, A.M.1
-
35
-
-
52049125207
-
AMP-activated protein kinase and hypoxic pulmonary vasoconstriction
-
Robertson, T.P. et al. 2008. AMP-activated protein kinase and hypoxic pulmonary vasoconstriction. Eur. J. Pharmacol. 595: 39-43.
-
(2008)
Eur. J. Pharmacol.
, vol.595
, pp. 39-43
-
-
Robertson, T.P.1
-
36
-
-
0013942378
-
Response of small pulmonary arteries to unilobar hypoxia and hypercapnia
-
Kato, M. & N.C. Staub. 1966. Response of small pulmonary arteries to unilobar hypoxia and hypercapnia. Circ. Res. 19: 426-440.
-
(1966)
Circ. Res.
, vol.19
, pp. 426-440
-
-
Kato, M.1
Staub, N.C.2
-
37
-
-
0035816735
-
Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ
-
Dipp, M. & A.M. Evans. 2001. Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ. Circ. Res. 89: 77-83.
-
(2001)
Circ. Res.
, vol.89
, pp. 77-83
-
-
Dipp, M.1
Evans, A.M.2
-
38
-
-
0026418298
-
Ca(2+)-induced Ca2+release in sea urchin egg homogenates: Modulation by cyclic ADP-ribose
-
Galione, A., H.C. Lee & W.B. Busa. 1991. Ca(2+)-induced Ca2+release in sea urchin egg homogenates: modulation by cyclic ADP-ribose. Science 253: 1143-1146.
-
(1991)
Science
, vol.253
, pp. 1143-1146
-
-
Galione, A.1
Lee, H.C.2
Busa, W.B.3
-
39
-
-
67349287016
-
NAADP mobilizes calcium from acidic organelles through two-pore channels
-
Calcraft, P.J. et al. 2009. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459: 596-600.
-
(2009)
Nature
, vol.459
, pp. 596-600
-
-
Calcraft, P.J.1
-
40
-
-
45449084433
-
Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle
-
Kinnear, N.P. et al. 2008. Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle. Cell Calcium 44: 190-201.
-
(2008)
Cell Calcium
, vol.44
, pp. 190-201
-
-
Kinnear, N.P.1
-
41
-
-
0038322079
-
Vasodilation by the calciummobilizing messenger cyclic ADP-ribose
-
Boittin, F.X. et al. 2003. Vasodilation by the calciummobilizing messenger cyclic ADP-ribose. J. Biol. Chem. 278: 9602-9608.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9602-9608
-
-
Boittin, F.X.1
-
42
-
-
77951251628
-
The role of intracellular ion channels in regulating cytoplasmic calcium in pulmonary arterial smooth muscle: Which store and where?
-
In Press
-
Evans, A.M. 2009. The role of intracellular ion channels in regulating cytoplasmic calcium in pulmonary arterial smooth muscle: which store and where? Adv. Exp. Med. Biol. In Press
-
(2009)
Adv. Exp. Med. Biol
-
-
Evans, A.M.1
-
43
-
-
0036487067
-
Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries
-
Smirnov, S.V. et al. 2002. Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries. J. Physiol. 538: 867-878.
-
(2002)
J. Physiol.
, vol.538
, pp. 867-878
-
-
Smirnov, S.V.1
-
44
-
-
33645452205
-
Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells
-
Platoshyn,O. et al. 2006. Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells. Am. J. Physiol. Cell Physiol. 290: C907-C916.
-
(2006)
Am. J. Physiol. Cell Physiol.
, vol.290
-
-
Platoshyn, O.1
-
45
-
-
49049107600
-
Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells
-
Firth, A.L., K.H. Yuill & S.V. Smirnov. 2008. Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 295: L61-L70.
-
(2008)
Am. J. Physiol. Lung Cell Mol. Physiol.
, vol.295
-
-
Firth, A.L.1
Yuill, K.H.2
Smirnov, S.V.3
-
46
-
-
0034658566
-
An oxygen-, acid- and anaesthetic-sensitive TASKlike background potassium channel in rat arterial chemoreceptor cells
-
Buckler, K.J., B.A. Williams & E. Honore. 2000. An oxygen-, acid- and anaesthetic-sensitive TASKlike background potassium channel in rat arterial chemoreceptor cells. J. Physiol. 525(Pt 1): 135-142.
-
(2000)
J. Physiol.
, vol.525
, Issue.PART 1
, pp. 135-142
-
-
Buckler, K.J.1
Williams, B.A.2
Honore., E.3
-
47
-
-
34247178517
-
AMP-activated protein kinase mediates carotid body excitation by hypoxia
-
Wyatt, C.N. et al. 2007. AMP-activated protein kinase mediates carotid body excitation by hypoxia. J. Biol. Chem. 282: 8092-8098.
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 8092-8098
-
-
Wyatt, C.N.1
-
48
-
-
0025000175
-
Hypoxic suppression of K+ currents in type i carotid body cells: Selective effect on the Ca2(+)-activated K+ current
-
Peers, C. 1990. Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current. Neurosci. Lett. 119: 253-256.
-
(1990)
Neurosci. Lett.
, vol.119
, pp. 253-256
-
-
Peers, C.1
-
49
-
-
1842329178
-
Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: Effect of hypoxia
-
Lopez-Lopez, J.R., C. Gonzalez & M.T. Perez- Garcia. 1997. Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: effect of hypoxia. J. Physiol. 499(Pt 2): 429-441.
-
(1997)
J. Physiol.
, vol.499
, Issue.PART 2
, pp. 429-441
-
-
Lopez-Lopez, J.R.1
Gonzalez, C.2
Garcia. Perez-, M.T.3
-
50
-
-
84934439950
-
Differential expression of oxygen sensitivity in voltage-dependent K channels in inbred strains of mice
-
discussion 351-359
-
Otsubo, T. et al. 2006. Differential expression of oxygen sensitivity in voltage-dependent K channels in inbred strains of mice. Adv. Exp. Med. Biol. 580: 209- 214; discussion 351-359.
-
(2006)
Adv. Exp. Med. Biol.
, vol.580
, pp. 209-214
-
-
Otsubo, T.1
-
51
-
-
0027446905
-
Properties of a transient K+ current in chemoreceptor cells of rabbit carotid body
-
López-Lopez, J.R., D.A. De Luís & C. González. 1993. Properties of a transient K+ current in chemoreceptor cells of rabbit carotid body. J. Physiol. 460: 15-32.
-
(1993)
J. Physiol.
, vol.460
, pp. 15-32
-
-
López-Lopez, J.R.1
Luís De, D.A.2
González, C.3
-
52
-
-
0037101233
-
Molecular identification of Kvalpha subunits that contribute to the oxygensensitive K+ current of chemoreceptor cells of the rabbit carotid body
-
Sánchez, D. et al. 2002. Molecular identification of Kvalpha subunits that contribute to the oxygensensitive K+ current of chemoreceptor cells of the rabbit carotid body. J. Physiol. 542: 369-382.
-
(2002)
J. Physiol.
, vol.542
, pp. 369-382
-
-
Sánchez, D.1
-
53
-
-
3042637605
-
Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing
-
Pérez-García, M.T. et al. 2004. Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing. J. Physiol. 557: 457-471.
-
(2004)
J. Physiol.
, vol.557
, pp. 457-471
-
-
Pérez-García, M.T.1
-
54
-
-
0028291271
-
Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type i cells
-
Buckler, K.J. & R.D. Vaughan-Jones. 1994. Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type I cells. J. Physiol. 476: 423-428.
-
(1994)
J. Physiol.
, vol.476
, pp. 423-428
-
-
Buckler, K.J.1
Vaughan-Jones, R.D.2
|