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Volumn 1177, Issue , 2009, Pages 89-100

Ion channel regulation by AMPK: The route of hypoxia-response coupling in the carotid body and pulmonary artery

Author keywords

AMP activated protein kinase (AMPK); Calcium; Carotid body; Hypoxia; Hypoxic pulmonary vasoconstriction (HPV); Pulmonary artery

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADENYLATE KINASE; ION CHANNEL;

EID: 70350365633     PISSN: 00778923     EISSN: 17496632     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.2009.05041.x     Document Type: Conference Paper
Times cited : (38)

References (54)
  • 1
    • 34648828532 scopus 로고    scopus 로고
    • AMP-activated/SNF1 protein kinases: Conserved guardians of cellular energy
    • Hardie,D.G. 2007. AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy. Nat. Rev. Mol. Cell. Biol. 8: 774-785.
    • (2007) Nat. Rev. Mol. Cell. Biol. , vol.8 , pp. 774-785
    • Hardied, G.1
  • 2
    • 20844451123 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
    • Kahn, B.B. et al. 2005. AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism. Cell Metab. 1: 15-25.
    • (2005) Cell Metab. , vol.1 , pp. 15-25
    • Kahn, B.B.1
  • 3
    • 33745215480 scopus 로고    scopus 로고
    • AMP-activated protein kinase and the regulation of Ca2+ signalling in O2-sensing cells
    • Evans, A.M. 2006. AMP-activated protein kinase and the regulation of Ca2+ signalling in O2-sensing cells. J. Physiol. 574: 113-123.
    • (2006) J. Physiol. , vol.574 , pp. 113-123
    • Evans, A.M.1
  • 4
    • 0035542970 scopus 로고    scopus 로고
    • AMP-activated protein kinase: The energy charge hypothesis revisited
    • Hardie, D.G. & S.A. Hawley. 2001. AMP-activated protein kinase: the energy charge hypothesis revisited. Bioessays 23: 1112-1119.
    • (2001) Bioessays , vol.23 , pp. 1112-1119
    • Hardie, D.G.1    Hawley, S.A.2
  • 5
    • 0345107247 scopus 로고    scopus 로고
    • Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMPactivated protein kinase cascade
    • Hawley, S.A. et al. 2003. Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMPactivated protein kinase cascade. J. Biol. 2: 28.
    • (2003) J. Biol. , vol.2 , pp. 28
    • Hawley, S.A.1
  • 6
    • 85047691317 scopus 로고    scopus 로고
    • CBS domains form energysensing modules whose binding of adenosine ligands is disrupted by disease mutations
    • Scott, J.W. et al. 2004. CBS domains form energysensing modules whose binding of adenosine ligands is disrupted by disease mutations. J. Clin. Invest. 113: 274-284.
    • (2004) J. Clin. Invest. , vol.113 , pp. 274-284
    • Scott, J.W.1
  • 7
    • 34848840368 scopus 로고    scopus 로고
    • Structural basis for AMP binding to mammalian AMP-activated protein kinase
    • Xiao, B. et al. 2007. Structural basis for AMP binding to mammalian AMP-activated protein kinase. Nature 449: 496-500.
    • (2007) Nature , vol.449 , pp. 496-500
    • Xiao, B.1
  • 8
    • 0029561919 scopus 로고
    • 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC
    • Davies, S.P. et al. 1995. 5′-AMP inhibits dephosphorylation, as well as promoting phosphorylation, of the AMP-activated protein kinase. Studies using bacterially expressed human protein phosphatase-2C alpha and native bovine protein phosphatase-2AC. FEBS Lett. 377: 421-425.
    • (1995) FEBS Lett. , vol.377 , pp. 421-425
    • Davies, S.P.1
  • 9
    • 33845949733 scopus 로고    scopus 로고
    • Dissecting the role of 5--AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase
    • Suter, M. et al. 2006. Dissecting the role of 5--AMP for allosteric stimulation, activation, and deactivation of AMP-activated protein kinase. J. Biol. Chem. 281: 32207-32216.
    • (2006) J. Biol. Chem. , vol.281 , pp. 32207-32216
    • Suter, M.1
  • 10
    • 67149111580 scopus 로고    scopus 로고
    • Adenylate kinase and AMP signaling networks: Metabolic monitoring, signal communication and body energy sensing
    • Dzeja, P. & A. Terzic. 2009. Adenylate kinase and AMP signaling networks: metabolic monitoring, signal communication and body energy sensing. Int. J. Mol. Sci. 10: 1729-1772.
    • (2009) Int. J. Mol. Sci. , vol.10 , pp. 1729-1772
    • Dzeja, P.1    Terzic., A.2
  • 11
    • 23044432463 scopus 로고    scopus 로고
    • Calmodulin-dependent protein kinase, kinase-beta is an alternative upstream kinase for AMP-activated protein kinase
    • Hawley, S.A. et al. 2005. Calmodulin-dependent protein kinase, kinase-beta is an alternative upstream kinase for AMP-activated protein kinase. Cell Metab. 2: 9-19.
    • (2005) Cell Metab. , vol.2 , pp. 9-19
    • Hawley, S.A.1
  • 12
    • 57849090443 scopus 로고    scopus 로고
    • The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor
    • McBride, A. et al. 2009. The glycogen-binding domain on the AMPK beta subunit allows the kinase to act as a glycogen sensor. Cell Metab. 9: 23-34.
    • (2009) Cell Metab. , vol.9 , pp. 23-34
    • McBride, A.1
  • 13
    • 0032529139 scopus 로고    scopus 로고
    • AMP-activated protein kinase: Greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform
    • Salt, I. et al. 1998. AMP-activated protein kinase: greater AMP dependence, and preferential nuclear localization, of complexes containing the alpha2 isoform. Biochem. J. 334(Pt 1): 177-187.
    • (1998) Biochem. J. , vol.334 , Issue.PART. 1 , pp. 177-187
    • Salt, I.1
  • 14
    • 33744541891 scopus 로고    scopus 로고
    • Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres
    • Gregor, M. et al. 2006. Plectin scaffolds recruit energy-controlling AMP-activated protein kinase (AMPK) in differentiated myofibres. J. Cell. Sci. 119: 1864-1875.
    • (2006) J. Cell. Sci. , vol.119 , pp. 1864-1875
    • Gregor, M.1
  • 15
    • 0031849916 scopus 로고    scopus 로고
    • Evidence for 5′ AMPactivated protein kinase mediation of the effect of muscle contraction on glucose transport
    • Hayashi, T. et al. 1998. Evidence for 5- AMPactivated protein kinase mediation of the effect of muscle contraction on glucose transport. Diabetes 47: 1369-1373.
    • (1998) Diabetes , vol.47 , pp. 1369-1373
    • Hayashi, T.1
  • 16
    • 0033820422 scopus 로고    scopus 로고
    • 5-aminoimidazole-4-carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes
    • Salt, I.P., J.M. Connell & G.W. Gould. 2000. 5-aminoimidazole-4- carboxamide ribonucleoside (AICAR) inhibits insulin-stimulated glucose transport in 3T3-L1 adipocytes. Diabetes 49: 1649-1656.
    • (2000) Diabetes , vol.49 , pp. 1649-1656
    • Salt, I.P.1    Connell, J.M.2    Gould, G.W.3
  • 17
    • 0016812869 scopus 로고
    • Loss of chemoreceptive properties of the rabbit carotid body after destruction of the glomus cells
    • Verna, A., M. Roumy & L.M. Leitner. 1975. Loss of chemoreceptive properties of the rabbit carotid body after destruction of the glomus cells. Brain Res. 100: 13-23.
    • (1975) Brain Res , vol.100 , pp. 13-23
    • Verna, A.1    Roumy, M.2    Leitner, L.M.3
  • 18
    • 0034890091 scopus 로고    scopus 로고
    • Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle
    • Dipp, M., P.C. Nye & A.M. Evans. 2001. Hypoxic release of calcium from the sarcoplasmic reticulum of pulmonary artery smooth muscle. Am. J. Physiol. Lung Cell Mol. Physiol. 281: L318-L325.
    • (2001) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.281
    • Dipp, M.1    Nye, P.C.2    Evans, A.M.3
  • 19
    • 0031956106 scopus 로고    scopus 로고
    • Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin
    • Gaine, S.P.,M.A. Hales & N.A. Flavahan. 1998. Hypoxic pulmonary endothelial cells release a diffusible contractile factor distinct from endothelin. Am. J. Physiol. 274: L657-L664.
    • (1998) Am. J. Physiol. , vol.274
    • Gaine, S.P.1    Hales, M.A.2    Flavahan, N.A.3
  • 20
    • 0027327956 scopus 로고
    • Oxygen sensing in airway chemoreceptors
    • Youngson, C. et al. 1993. Oxygen sensing in airway chemoreceptors. Nature 365: 153-155.
    • (1993) Nature , vol.365 , pp. 153-155
    • Youngson, C.1
  • 21
    • 0031028005 scopus 로고    scopus 로고
    • Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells
    • Thompson, R.J., A. Jackson & C.A. Nurse. 1997. Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells. J. Physiol. 498(Pt 2): 503-510.
    • (1997) J. Physiol. , vol.498 , Issue.PART 2 , pp. 503-510
    • Thompson, R.J.1    Jackson, A.2    Nurse, C.A.3
  • 22
    • 0025959327 scopus 로고
    • Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture
    • Stea, A. & C.A. Nurse. 1991. Whole-cell and perforated-patch recordings from O2-sensitive rat carotid body cells grown in short- and long-term culture. Pflugers Arch. 418: 93-101.
    • (1991) Pflugers Arch , vol.418 , pp. 93-101
    • Stea, A.1    Nurse, C.A.2
  • 23
    • 0026767130 scopus 로고
    • Relative mitochondrial membrane potential and [Ca2+]i in type i cells isolated from the rabbit carotid body
    • Duchen, M.R. & T.J. Biscoe. 1992. Relative mitochondrial membrane potential and [Ca2+]i in type I cells isolated from the rabbit carotid body. J. Physiol. 450: 33-61.
    • (1992) J. Physiol. , vol.450 , pp. 33-61
    • Duchen, M.R.1    Biscoe, T.J.2
  • 24
    • 0026703693 scopus 로고
    • Mitochondrial function in type i cells isolated from rabbit arterial chemoreceptors
    • Duchen, M.R. & T.J. Biscoe. 1992. Mitochondrial function in type I cells isolated from rabbit arterial chemoreceptors. J. Physiol. 450: 13-31.
    • (1992) J. Physiol. , vol.450 , pp. 13-31
    • Duchen, M.R.1    Biscoe, T.J.2
  • 25
    • 0029953806 scopus 로고    scopus 로고
    • Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery
    • Shigemori,K. et al. 1996. Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery. Am. J. Physiol. 270: L803-L809.
    • (1996) Am. J. Physiol. , vol.270
    • Shigemori, K.1
  • 26
    • 41949089941 scopus 로고    scopus 로고
    • Functional mitochondria are required forO2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells
    • Buttigieg, J. et al. 2008. Functional mitochondria are required forO2 but not CO2 sensing in immortalized adrenomedullary chromaffin cells. Am. J. Physiol. Cell Physiol. 294: C945-C956.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.294
    • Buttigieg, J.1
  • 27
    • 0032052209 scopus 로고    scopus 로고
    • Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase
    • Gnaiger, E. et al. 1998. Mitochondrial oxygen affinity, respiratory flux control and excess capacity of cytochrome c oxidase. J. Exp. Biol. 201: 1129-1139.
    • (1998) J. Exp. Biol. , vol.201 , pp. 1129-1139
    • Gnaiger, E.1
  • 28
    • 0028053910 scopus 로고
    • Carotid body chemoreceptors: From natural stimuli to sensory discharges
    • Gonzalez, C. et al. 1994. Carotid body chemoreceptors: from natural stimuli to sensory discharges. Physiol. Rev. 74: 829-898.
    • (1994) Physiol. Rev. , vol.74 , pp. 829-898
    • Gonzalez, C.1
  • 29
    • 0019378297 scopus 로고
    • Cat carotid body: Oxygen consumption and other parameters
    • Whalen, W.J. et al. 1981. Cat carotid body: oxygen consumption and other parameters. J. Appl. Physiol. 50: 129-133.
    • (1981) J. Appl. Physiol. , vol.50 , pp. 129-133
    • Whalen, W.J.1
  • 30
    • 9144224900 scopus 로고    scopus 로고
    • Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs
    • Weissmann, N. et al. 2003. Effects of mitochondrial inhibitors and uncouplers on hypoxic vasoconstriction in rabbit lungs. Am. J. Respir. Cell. Mol. Biol. 29: 721-732.
    • (2003) Am. J. Respir. Cell. Mol. Biol. , vol.29 , pp. 721-732
    • Weissmann, N.1
  • 31
    • 37349041710 scopus 로고    scopus 로고
    • Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease
    • Hardie, D.G. 2008. Role of AMP-activated protein kinase in the metabolic syndrome and in heart disease. FEBS Lett. 582: 81-89.
    • (2008) FEBS Lett. , vol.582 , pp. 81-89
    • Hardie, D.G.1
  • 32
    • 28844433635 scopus 로고    scopus 로고
    • The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin
    • Shaw, R.J. et al. 2005. The kinase LKB1 mediates glucose homeostasis in liver and therapeutic effects of metformin. Science 310: 1642-1646.
    • (2005) Science , vol.310 , pp. 1642-1646
    • Shaw, R.J.1
  • 33
    • 0025865055 scopus 로고
    • Energy state and vasomotor tone in hypoxic pig lungs
    • Buescher, P.C. et al. 1991. Energy state and vasomotor tone in hypoxic pig lungs. J. Appl. Physiol. 70: 1874-1881.
    • (1991) J. Appl. Physiol. , vol.70 , pp. 1874-1881
    • Buescher, P.C.1
  • 34
    • 29244463866 scopus 로고    scopus 로고
    • Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells?
    • Evans, A.M. et al. 2005. Does AMP-activated protein kinase couple inhibition of mitochondrial oxidative phosphorylation by hypoxia to calcium signaling in O2-sensing cells? J. Biol. Chem. 280: 41504-41511.
    • (2005) J. Biol. Chem. , vol.280 , pp. 41504-41511
    • Evans, A.M.1
  • 35
    • 52049125207 scopus 로고    scopus 로고
    • AMP-activated protein kinase and hypoxic pulmonary vasoconstriction
    • Robertson, T.P. et al. 2008. AMP-activated protein kinase and hypoxic pulmonary vasoconstriction. Eur. J. Pharmacol. 595: 39-43.
    • (2008) Eur. J. Pharmacol. , vol.595 , pp. 39-43
    • Robertson, T.P.1
  • 36
    • 0013942378 scopus 로고
    • Response of small pulmonary arteries to unilobar hypoxia and hypercapnia
    • Kato, M. & N.C. Staub. 1966. Response of small pulmonary arteries to unilobar hypoxia and hypercapnia. Circ. Res. 19: 426-440.
    • (1966) Circ. Res. , vol.19 , pp. 426-440
    • Kato, M.1    Staub, N.C.2
  • 37
    • 0035816735 scopus 로고    scopus 로고
    • Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ
    • Dipp, M. & A.M. Evans. 2001. Cyclic ADP-ribose is the primary trigger for hypoxic pulmonary vasoconstriction in the rat lung in situ. Circ. Res. 89: 77-83.
    • (2001) Circ. Res. , vol.89 , pp. 77-83
    • Dipp, M.1    Evans, A.M.2
  • 38
    • 0026418298 scopus 로고
    • Ca(2+)-induced Ca2+release in sea urchin egg homogenates: Modulation by cyclic ADP-ribose
    • Galione, A., H.C. Lee & W.B. Busa. 1991. Ca(2+)-induced Ca2+release in sea urchin egg homogenates: modulation by cyclic ADP-ribose. Science 253: 1143-1146.
    • (1991) Science , vol.253 , pp. 1143-1146
    • Galione, A.1    Lee, H.C.2    Busa, W.B.3
  • 39
    • 67349287016 scopus 로고    scopus 로고
    • NAADP mobilizes calcium from acidic organelles through two-pore channels
    • Calcraft, P.J. et al. 2009. NAADP mobilizes calcium from acidic organelles through two-pore channels. Nature 459: 596-600.
    • (2009) Nature , vol.459 , pp. 596-600
    • Calcraft, P.J.1
  • 40
    • 45449084433 scopus 로고    scopus 로고
    • Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle
    • Kinnear, N.P. et al. 2008. Lysosomes co-localize with ryanodine receptor subtype 3 to form a trigger zone for calcium signalling by NAADP in rat pulmonary arterial smooth muscle. Cell Calcium 44: 190-201.
    • (2008) Cell Calcium , vol.44 , pp. 190-201
    • Kinnear, N.P.1
  • 41
    • 0038322079 scopus 로고    scopus 로고
    • Vasodilation by the calciummobilizing messenger cyclic ADP-ribose
    • Boittin, F.X. et al. 2003. Vasodilation by the calciummobilizing messenger cyclic ADP-ribose. J. Biol. Chem. 278: 9602-9608.
    • (2003) J. Biol. Chem. , vol.278 , pp. 9602-9608
    • Boittin, F.X.1
  • 42
    • 77951251628 scopus 로고    scopus 로고
    • The role of intracellular ion channels in regulating cytoplasmic calcium in pulmonary arterial smooth muscle: Which store and where?
    • In Press
    • Evans, A.M. 2009. The role of intracellular ion channels in regulating cytoplasmic calcium in pulmonary arterial smooth muscle: which store and where? Adv. Exp. Med. Biol. In Press
    • (2009) Adv. Exp. Med. Biol
    • Evans, A.M.1
  • 43
    • 0036487067 scopus 로고    scopus 로고
    • Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries
    • Smirnov, S.V. et al. 2002. Electrophysiologically distinct smooth muscle cell subtypes in rat conduit and resistance pulmonary arteries. J. Physiol. 538: 867-878.
    • (2002) J. Physiol. , vol.538 , pp. 867-878
    • Smirnov, S.V.1
  • 44
    • 33645452205 scopus 로고    scopus 로고
    • Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells
    • Platoshyn,O. et al. 2006. Acute hypoxia selectively inhibits KCNA5 channels in pulmonary artery smooth muscle cells. Am. J. Physiol. Cell Physiol. 290: C907-C916.
    • (2006) Am. J. Physiol. Cell Physiol. , vol.290
    • Platoshyn, O.1
  • 45
    • 49049107600 scopus 로고    scopus 로고
    • Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells
    • Firth, A.L., K.H. Yuill & S.V. Smirnov. 2008. Mitochondria-dependent regulation of Kv currents in rat pulmonary artery smooth muscle cells. Am. J. Physiol. Lung Cell Mol. Physiol. 295: L61-L70.
    • (2008) Am. J. Physiol. Lung Cell Mol. Physiol. , vol.295
    • Firth, A.L.1    Yuill, K.H.2    Smirnov, S.V.3
  • 46
    • 0034658566 scopus 로고    scopus 로고
    • An oxygen-, acid- and anaesthetic-sensitive TASKlike background potassium channel in rat arterial chemoreceptor cells
    • Buckler, K.J., B.A. Williams & E. Honore. 2000. An oxygen-, acid- and anaesthetic-sensitive TASKlike background potassium channel in rat arterial chemoreceptor cells. J. Physiol. 525(Pt 1): 135-142.
    • (2000) J. Physiol. , vol.525 , Issue.PART 1 , pp. 135-142
    • Buckler, K.J.1    Williams, B.A.2    Honore., E.3
  • 47
    • 34247178517 scopus 로고    scopus 로고
    • AMP-activated protein kinase mediates carotid body excitation by hypoxia
    • Wyatt, C.N. et al. 2007. AMP-activated protein kinase mediates carotid body excitation by hypoxia. J. Biol. Chem. 282: 8092-8098.
    • (2007) J. Biol. Chem. , vol.282 , pp. 8092-8098
    • Wyatt, C.N.1
  • 48
    • 0025000175 scopus 로고
    • Hypoxic suppression of K+ currents in type i carotid body cells: Selective effect on the Ca2(+)-activated K+ current
    • Peers, C. 1990. Hypoxic suppression of K+ currents in type I carotid body cells: selective effect on the Ca2(+)-activated K+ current. Neurosci. Lett. 119: 253-256.
    • (1990) Neurosci. Lett. , vol.119 , pp. 253-256
    • Peers, C.1
  • 49
    • 1842329178 scopus 로고    scopus 로고
    • Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: Effect of hypoxia
    • Lopez-Lopez, J.R., C. Gonzalez & M.T. Perez- Garcia. 1997. Properties of ionic currents from isolated adult rat carotid body chemoreceptor cells: effect of hypoxia. J. Physiol. 499(Pt 2): 429-441.
    • (1997) J. Physiol. , vol.499 , Issue.PART 2 , pp. 429-441
    • Lopez-Lopez, J.R.1    Gonzalez, C.2    Garcia. Perez-, M.T.3
  • 50
    • 84934439950 scopus 로고    scopus 로고
    • Differential expression of oxygen sensitivity in voltage-dependent K channels in inbred strains of mice
    • discussion 351-359
    • Otsubo, T. et al. 2006. Differential expression of oxygen sensitivity in voltage-dependent K channels in inbred strains of mice. Adv. Exp. Med. Biol. 580: 209- 214; discussion 351-359.
    • (2006) Adv. Exp. Med. Biol. , vol.580 , pp. 209-214
    • Otsubo, T.1
  • 51
    • 0027446905 scopus 로고
    • Properties of a transient K+ current in chemoreceptor cells of rabbit carotid body
    • López-Lopez, J.R., D.A. De Luís & C. González. 1993. Properties of a transient K+ current in chemoreceptor cells of rabbit carotid body. J. Physiol. 460: 15-32.
    • (1993) J. Physiol. , vol.460 , pp. 15-32
    • López-Lopez, J.R.1    Luís De, D.A.2    González, C.3
  • 52
    • 0037101233 scopus 로고    scopus 로고
    • Molecular identification of Kvalpha subunits that contribute to the oxygensensitive K+ current of chemoreceptor cells of the rabbit carotid body
    • Sánchez, D. et al. 2002. Molecular identification of Kvalpha subunits that contribute to the oxygensensitive K+ current of chemoreceptor cells of the rabbit carotid body. J. Physiol. 542: 369-382.
    • (2002) J. Physiol. , vol.542 , pp. 369-382
    • Sánchez, D.1
  • 53
    • 3042637605 scopus 로고    scopus 로고
    • Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing
    • Pérez-García, M.T. et al. 2004. Characterization of the Kv channels of mouse carotid body chemoreceptor cells and their role in oxygen sensing. J. Physiol. 557: 457-471.
    • (2004) J. Physiol. , vol.557 , pp. 457-471
    • Pérez-García, M.T.1
  • 54
    • 0028291271 scopus 로고
    • Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type i cells
    • Buckler, K.J. & R.D. Vaughan-Jones. 1994. Effects of hypoxia on membrane potential and intracellular calcium in rat neonatal carotid body type I cells. J. Physiol. 476: 423-428.
    • (1994) J. Physiol. , vol.476 , pp. 423-428
    • Buckler, K.J.1    Vaughan-Jones, R.D.2


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