A QSAR study on indole-based PPAR-γ agonists in respect to receptor binding and gene transactivation data

QSAR and Combinatorial Science

Volumn 28, Issue 8, 2009, Pages 802-805

  Giaginis, Costas ^a,b   Theocharis, Stamacios ^b   Tsantili Kakoulidou, Anna ^a  

^a UNIVERSITY OF ATHENS   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

Gene transactivation; Indole derivatives; Medicinal chemistry; Multivariate data analysis; PPAR ligands; Receptor binding; Receptors

Indexed keywords

COMPUTATIONAL CHEMISTRY; DATA HANDLING; INFORMATION ANALYSIS; MULTIVARIANT ANALYSIS; POLYCYCLIC AROMATIC HYDROCARBONS; REGRESSION ANALYSIS;

GENE TRANSACTIVATION; INDOLE DERIVATIVES; MEDICINAL CHEMISTRY; MULTIVARIATE DATA ANALYSIS; PLS MODELLING; PPAR-Γ LIGAND; QSAR STUDIES; RECEPTOR; RECEPTOR BINDING; TRANSACTIVATION;

GENES;

HALOGEN; INDOLE DERIVATIVE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; ROSIGLITAZONE;

CONFERENCE PAPER; DATA ANALYSIS; DRUG RECEPTOR BINDING; LIPOPHILICITY; MOLECULAR WEIGHT; MULTIPLE REGRESSION; MULTIVARIATE ANALYSIS; PARTIAL LEAST SQUARES REGRESSION; PHYSICAL CHEMISTRY; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; STATISTICAL ANALYSIS; STATISTICAL MODEL; TRANSACTIVATION;

EID: 70350354816     PISSN: 1611020X     EISSN: 16110218     Source Type: Journal    
DOI: 10.1002/qsar.200860185     Document Type: Conference Paper

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