RET expression and neuron-like differentiation of pheochromocytoma and normal chromaffin cells

Hormone and Metabolic Research

Volumn 41, Issue 9, 2009, Pages 710-714

  Powers, J F ^a   Picard, K L ^a   Tischler, A S ^a  

^a TUFTS MEDICAL CENTER   (United States)

Author keywords

Adrenal medulla; Nerve growth factor; Neuroendocrine tumor; Paraganglioma

Indexed keywords

CYCLIC AMP; NERVE GROWTH FACTOR; PROTEIN RET;

ADRENAL MEDULLA; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL STRAIN; CHROMAFFIN CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; MOUSE; NERVE CELL DIFFERENTIATION; NERVE FIBER GROWTH; NONHUMAN; PARAGANGLIOMA; PHEOCHROMOCYTOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; STEM CELL; UPREGULATION; WILD TYPE;

ADRENAL GLAND NEOPLASMS; ANIMALS; CELL DIFFERENTIATION; CELL LINE; CELLS, CULTURED; CHROMAFFIN CELLS; GENE EXPRESSION; HUMANS; MICE; NEUROGENESIS; NEURONS; PC12 CELLS; PHEOCHROMOCYTOMA; PROTO-ONCOGENE PROTEINS C-RET; RATS;

RATTUS;

EID: 70350352185     PISSN: 00185043     EISSN: 14394286     Source Type: Journal    
DOI: 10.1055/s-0029-1224136     Document Type: Article

References (18)

1. Powers JF, Brachold JM, Tischler AS. Ret protein expression in adrenal medullary hyperplasia and pheochromocytoma. Endocr Pathol 2003 14 351-361
2. Takaya K, Yoshimasa T, Arai H, Tamura N, Miyamoto Y, Itoh H, Nakao K. Expression of the ret proto-oncogene in normal human tissues, pheochromocytomas, and other tumors of neural crest origin. J Mol Med 1996 74 617-621
3. Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP, Farese RV, Freeman RS, Carter BD, Kaelin WG Jr, Schlisio S. Neuronal apoptosis linked to egln3 prolyl hydroxylase and familial pheochromocytoma genes: Developmental culling and cancer. Cancer Cell 2005 8 155-167
4. Lai AZ, Gujral TS, Mulligan LM. Ret signaling in endocrine tumors: Delving deeper into molecular mechanisms. Endocr Pathol 2007 18 57-67
5. Krieglstein K, Deimling F, Suter-Crazzolara C, Unsicker K. Expression and localization of GDNF in developing and adult adrenal chromaffin cells. Cell Tissue Res 1996 286 263-268 (Pubitemid 26383674)
6. Forander P, Broberger C, Stromberg I. Glial-cell-line-derived neurotrophic factor induces nerve fibre formation in primary cultures of adrenal chromaffin cells. Cell Tissue Res 2001 305 43-51
7. Tischler AS, Greene LA. Phenotypic plasticity of pheochromocytoma and normal adrenal medullary cells. Adv Biochem Psychopharmacol 1980 25 61-68
8. Tischler AS, DeLellis RA, Biales B, Nunnemacher G, Carabba V, Wolfe HJ. Nerve growth factor-induced neurite outgrowth from normal human chromaffin cells. Lab Invest 1980 43 399-409
9. Powers JF, Shahsavari M, Tsokas P, Tischler AS. Nerve growth factor receptor signaling in proliferation of normal adult rat chromaffin cells. Cell Tissue Res 1999 295 21-32
10. Marek L, Levresse V, Amura C, Zentrich E, Van Putten V, Nemenoff RA, Heasley LE. Multiple signaling conduits regulate global differentiation-specific gene expression in pc12 cells. J Cell Physiol 2004 201 459-469
11. Batistatou A, Greene LA. Internucleosomal DNA cleavage and neuronal cell survival/death. J Cell Biol 1993 122 523-532
12. Greene LA, Tischler AS. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 1976 73 2424-2428
13. Powers JF, Evinger MJ, Tsokas P, Bedri S, Alroy J, Shahsavari M, Tischler AS. Pheochromocytoma cell lines from heterozygous neurofibromatosis knockout mice. Cell Tissue Res 2000 302 309-320
14. Powers JF, Evinger MJ, Zhi J, Picard KL, Tischler AS. Pheochromocytomas in nf1 knockout mice express a neural progenitor gene expression profile. Neuroscience 2007 147 928-937
15. Powers JF, Schelling KH, Brachold JM, Tischler AS. Plasticity of pheochromocytoma cell lines from neurofibromatosis knockout mice. Ann N Y Acad Sci 2002 971 371-378
16. Evinger MJ, Powers JF, Tischler AS. Transcriptional silencing of glucocorticoid-inducible phenylethanolamine N-methyltransferase expression by sequential signaling events. Exp Cell Res 2007 313 772-781
17. Kaufmann SH, Desnoyers S, Ottaviano Y, Davidson NE, Poirier GG. Specific proteolytic cleavage of poly(adp-ribose) polymerase: An early marker of chemotherapy-induced apoptosis. Cancer Res 1993 53 3976-3985
18. Rossel M, Pasini A, Chappuis S, Geneste O, Fournier L, Schuffenecker I, Takahashi M, van Grunsven LA, Urdiales JL, Rudkin BB, Lenoir GM, Billaud M. Distinct biological properties of two ret isoforms activated by MEN 2a and MEN 2b mutations. Oncogene 1997 14 265 275