Aqueous extract of Zanthoxylum schinifolium elicits contractile and secretory responses via β1-adrenoceptor activation in beating rabbit atria

Journal of Ethnopharmacology

Volumn 126, Issue 2, 2009, Pages 300-307

  Cui, Hao Zhen ^a   Choi, Hye Ran ^a   Choi, Deok Ho ^a   Cho, Kyung Woo ^a   Kang, Dae Gill ^a   Lee, Ho Sub ^a  

^a Wonkwang University   (South Korea)

Author keywords

1 Adrenoceptor; Atrial dynamics; Atrial natriuretic peptide; cAMP; L type Ca2+ channel; Zanthoxylum schinifolium

Indexed keywords

3 ISOPROPYLAMINO 1 (7 METHYL 4 INDANYLOXY) 2 BUTANOL; 5 [2 [[2 HYDROXY 3 [4 (1 METHYL 4 TRIFLUOROMETHYL 2 IMIDAZOLYL)PHENOXY]PROPYL]AMINO]ETHOXY]SALICYLAMIDE; ATRIAL NATRIURETIC FACTOR; BETA 1 ADRENERGIC RECEPTOR; CALCIUM CHANNEL L TYPE; CYCLIC AMP; DILTIAZEM; KT 5720; PLANT EXTRACT; PROPRANOLOL; UNCLASSIFIED DRUG; ZANTHOXYLUM SCHINIFOLIUM EXTRACT;

ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; HEART ATRIUM CONTRACTION; HEART STROKE VOLUME; INOTROPISM; ISOLATED HEART; MALE; NONHUMAN; PROTEIN SECRETION; PULSE PRESSURE; RABBIT; SIGNAL TRANSDUCTION; SOLVENT EXTRACTION; ZANTHOXYLUM; ZANTHOXYLUM SCHINIFOLIUM;

ANIMALS; ATRIAL NATRIURETIC FACTOR; BLOOD PRESSURE; CARBAZOLES; CARDIOTONIC AGENTS; CARDIOVASCULAR AGENTS; CYCLIC AMP; DILTIAZEM; HEART ATRIA; HEMODYNAMICS; IMIDAZOLES; PLANT EXTRACTS; PLANT LEAVES; PLANT STEMS; PROPANOLAMINES; PROPRANOLOL; PYRROLES; RABBITS; RECEPTORS, ADRENERGIC, BETA-1; STROKE VOLUME; ZANTHOXYLUM;

ORYCTOLAGUS CUNICULUS; ZANTHOXYLUM SCHINIFOLIUM;

EID: 70350344983     PISSN: 03788741     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jep.2009.08.025     Document Type: Article

References (19)

1. Bers D.M. Cardiac excitation-contraction coupling. Nature 415 (2002) 198-205
2. Brodde O.-E., and Michel M.C. Adrenergic and muscarinic receptors in the human heart. Pharmacological Reviews 51 (1999) 651-689
3. Brodde O.-E., and Kirsten L. Autonomic receptor systems in the failing and aging human heart: similarities and differences. European Journal of Pharmacology 500 (2004) 167-176
4. Bylund D.B., Eikenberg D.C., Hieble J.P., Langer S.Z., Lefkowitz R.J., Minneman K.P., Molinoff P.B., Ruffolo R.R., and Trendelenburg U. International Union of Pharmacology Nomenclature of Adrenoceptors. Pharmacological Reviews 46 (1994) 121-136
5. Cao L.H., Lee Y.J., Kang D.G., Kim J.S., and Lee H.S. Effect of Zanthoxylum schinifolium on TNF-α-induced vascular inflammation in human umbilical vein endothelial cells. Vascular Pharmacology 50 (2009) 200-207
6. Chen I.S., Lin Y.C., Tsai I.L., Teng C.M., Ko F.N., Ishikawa T., and Ishii H. Coumarins and anti-platelet aggregation constituents from Zanthoxylum schinifolium. Phytochemistry 39 (1995) 1091-1097
7. Cheng M.J., Cheng C.H., and Lin W.Y. Chemical constituents from the leaves of Zanthoxylum schinifolium. Journal of the Chinese Chemical Society 49 (2002) 125-128
8. Cho K.W., Kim S.H., Kim C.H., and Seul K.H. Mechanical basis of ANP secretion in beating atria: atrial stroke volume and ECF translocation. American Journal of Physiology 268 (1995) 1129-1136
9. Cho K.W., Lee S.J., Wen J.F., Kim S.H., Seul K.H., and Lee H.S. Mechanical control of extracellular space in rabbit atria: an intimate modulator of the translocation of extracellular fluid and released atrial natriuretic peptide. Experimental Physiology 87 (2002) 185-194
10. Choi D.H., Kang D.G., Cui X., Cho K.W., Sohn E.J., Kim J.S., and Lee H.S. The positive inotropic effect of the aqueous extract of Convallaria keiskei in beating rabbit atria. Life Science 79 (2006) 1178-1185
11. Chon S.U., Heo B.G., Park Y.S., Kim D.K., and Gorinstein S. Total phenolics level, antioxidant activities and cytotoxicity of young sprouts of some traditional Korean salad plants. Plant Foods for Human Nutrition 64 (2009) 25-31
12. 2+-independent cAMP inhibition of ANP release in beating rabbit atria. American Journal of Physiology-Regulatory Integrative Comparative Physiology 282 (2002) 1477-1489
13. De Bold A.J. Atrial natriuretic factor: a hormone produced by the heart. Science 230 (1985) 767-770
14. Jo Y.S., Huong D.T., Bae K., Lee M.K., and Kim Y.H. Monoamine oxidase inhibitory coumarin from Zanthoxylum schinifolium. Planta Medica 68 (2002) 84-85
15. Kaumann A.J., and Molenaar P. Modulation of human cardiac function through 4 beta-adrenoceptor populations. Naunyn-Schmiedeberg's Archives of Pharmacology 355 (1997) 667-681
16. Paik S.Y., Koh K.H., Beak S.M., Paek S.H., and Kim J.A. The essential oils from Zanthoxylum schinifolium pericarp induce apoptosis of HepG2 human hepatoma cells through increased production of reactive oxygen species. Biological Pharmaceutical Bulletin 28 (2005) 802-807
17. Ruskoaho H. Atrial natriuretic peptide: synthesis, release, and metabolism. Pharmacological Reviews 44 (1992) 479-601
18. 2+ channels in regulation of atrial ANP release. American Journal of Physiology, Heart and Circulatory Physiology 279 (2000) 2879-2888
19. Yang X.G. Aroma constituents and alkylamides of red and green Huajiao (Zanthoxylum bungeanum and Zanthoxylum schinifolium). Journal of Agricultural and Food Chemistry 56 (2008) 1689-1696