Brain metastases from testicular germ cell tumors: A retrospective analysis: Original Article: Clinical Investigation

International Journal of Urology

Volumn 16, Issue 11, 2009, Pages 887-893

  Nonomura, Norio ^a   Nagahara, Akira ^a   Oka, Daizo ^a   Mukai, Masatoshi ^a   Nakai, Yasutomo ^a   Nakayama, Masashi ^a   Nishimura, Kazuo ^a   Kakimoto, Kennichi ^b   Nakamura, Terukazu ^c   Usami, Michiyuki ^b   Okuyama, Akihiko ^a   Miki, Tsuneharu ^c  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA MEDICAL CENTER FOR CANCER AND CARDIOVASCULAR DISEASES   (Japan)

^c KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Brain metastasis; Chemotherapy; Germ cell tumor; Surgery; Testicular cancer

Indexed keywords

BLEOMYCIN; CARBOPLATIN; CISPLATIN; CYCLOPHOSPHAMIDE; DACTINOMYCIN; ETOPOSIDE; GEMCITABINE; IFOSFAMIDE; IRINOTECAN; NEDAPLATIN; PACLITAXEL; TENIPOSIDE; VINBLASTINE; VINCRISTINE;

ADULT; ARTICLE; BRAIN METASTASIS; CANCER CHEMOTHERAPY; CANCER RADIOTHERAPY; CANCER SURVIVAL; CLINICAL ARTICLE; DRUG MEGADOSE; GERM CELL TUMOR; HUMAN; MALE; NON SEMINOMATOUS GERMINOMA; PRIORITY JOURNAL; PROGNOSIS; SEMINOMA; STEREOTACTIC RADIOSURGERY; TUMOR CLASSIFICATION;

ADULT; BRAIN NEOPLASMS; HUMANS; MALE; NEOPLASMS, GERM CELL AND EMBRYONAL; RETROSPECTIVE STUDIES; TESTICULAR NEOPLASMS; YOUNG ADULT;

EID: 70350318932     PISSN: 09198172     EISSN: 14422042     Source Type: Journal    
DOI: 10.1111/j.1442-2042.2009.02391.x     Document Type: Article

References (27)

1. Devesa SS, Blot WJ, Stone BJ, Miller BA, Tarone RE, Fraumeni JF Jr. Recent cancer trends in the United States. J. Natl. Cancer Inst. 1995 87 : 175 82.
2. Sheinfeld J, Bajorin D. Management of the postchemotherapy residual mass. Urol. Clin. North Am. 1993 20 : 133 43.
3. Bosl GJ, Motzer RJ. Testicular germ-cell cancer. N. Engl. J. Med. 1997 337 : 242 53.
4. International Germ Cell Cancer Collaborative Group. International germ cell consensus classification: a prognostic factor-based staging system for metastatic germ cell cancers. Germ Cell Cancer J. Clin. Oncol. 1997 15 : 594 603.
5. Raina V, Singh SP, Kamble N et al. Brain metastasis as the site of relapse in germ cell tumor of testis. Cancer 1993 72 : 2182 5.
6. Bower M, Newlands ES, Holden L, Rustin GJ, Begent RH. Treatment of men with metastatic non-seminomatous germ cell tumours with cyclical POMB/ACE chemotherapy. Ann. Oncol. 1997 8 : 477 83.
7. Bokemeyer C, Nowak P, Haupt A et al. Treatment of brain metastases in patients with testicular cancer. J. Clin. Oncol. 1997 15 : 1449 54.
8. Fossa SD, Bokemeyer C, Gerl A et al. Treatment outcome of patients with brain metastases from malignant germ cell tumors. Cancer 1999 85 : 988 97.
9. Williams SD, Einhorn LH. Brain metastases in disseminated germinal neoplasms: incidence and clinical course. Cancer 1979 44 : 1514 16.
10. Kaye SB, Bagshawe KD, McElwain TJ, Peckham MJ. Brain metastases in malignant teratoma: a review of four years' experience and an assessment of the role of tumour markers. Br. J. Cancer 1979 39 : 217 23.
11. Spears WT, Morphis JG II., Lester SG, Williams SD, Einhorn LH. Brain metastases and testicular tumors: long-term survival. Int. J. Radiat. Oncol. Biol. Phys. 1992 22 : 17 22.
12. Gerl A, Clemm C, Kohl P, Schalhorn A, Wilmanns W. Central nervous system as sanctuary site of relapse in patients treated with chemotherapy for metastatic testicular cancer. Clin. Exp. Metastasis 1994 12 : 226 30.
13. Kollmannsberger C, Nichols C, Bamberg M et al. First-line high-dose chemotherapy +/- radiation therapy in patients with metastatic germ-cell cancer and brain metastases. Ann. Oncol. 2000 11 : 553 9.
14. Azar JM, Schneider BP, Einhorn LH. Is the blood-brain barrier relevant in metastatic germ cell tumor? Int. J. Radiat. Oncol. Biol. Phys. 2007 69 : 163 6.
15. Bart J, Groen HJ, Hendrikse NH, van der Graaf WT, Vaalburg W, de Vries EG. The blood-brain barrier and oncology: new insights into function and modulation. Cancer Treat. Rev. 2000 26 : 449 62.
16. Regina A, Demeule M, Laplante A et al. Multidrug resistance in brain tumors: roles of the blood-brain barrier. Cancer Metastasis Rev. 2001 20 : 13 25.
17. Warren K, Gervais A, Aikin A, Egorin M, Balis FM. Pharmacokinetics of carboplatin administered with lobradimil to pediatric patients with brain tumors. Cancer Chemother. Pharmacol. 2004 54 : 206 12.
18. Sobin LH, Wittekind Ch (eds). TNM Classification of Malignant Tumors, 6th edn. John Wiley & Sons, Hoboken, NJ, 2002.
19. The Japanese Urological Association and the Japanese Pathological Society. General Rule for Clinical and Pathological Studies on Testicular Tumors, 3rd edn. Kanehara Shuppan, Tokyo, 2005.
20. Klos KJ, O'Neill BP. Brain metastases. Neurologist 2004 10 : 31 46.
21. Mahalati K, Bilen CY, Ozen H, Aki FT, Kendi S. The management of brain metastasis in nonseminomatous germ cell tumours. BJU Int. 1999 83 : 457 61.
22. Salvati M, Piccirilli M, Raco A et al. Brain metastasis from non-seminomatous germ cell tumors of the testis: indications for aggressive treatment. Neurosurg. Rev. 2006 29 : 130 7.
23. Mathews VP, Broome DR, Smith RR, Bognanno JR, Einhorn LH, Edwards MK. Neuroimaging of disseminated germ cell neoplasms. AJNR Am. J. Neuroradiol. 1990 11 : 319 24.
24. Ginsberg S, Kirshner J, Reich S et al. Systemic chemotherapy for a primary germ cell tumor of the brain: a pharmacokinetic study. Cancer Treat. 1981 65 : 477 83.
25. Bokemeyer C, Schmoll HJ. Treatment of advanced germ cell tumours by dose intensified chemotherapy with haematopoietic growth factors or peripheral blood stem cells (PBSC). Eur. Urol. 1993 23 : 223 9.
26. Broun ER, Sledge GW, Einhorn LH, Tricot GJ. High-dose carboplatin and mitoxantrone with autologous bone marrow support in the treatment of advanced breast cancer. Am. J. Clin. Oncol. 1993 16 : 9 13.
27. Sawrie SM, Guthrie BL, Spencer SA et al. Predictors of distant brain recurrence for patients with newly diagnosed brain metastases treated with stereotactic radiosurgery alone. Int. J. Radiat. Oncol. Biol. Phys. 2008 70 : 181 6.