Pulsed electron-electron double-resonance determination of spin-label distances and orientations on the tetrameric potassium ion channel KcsA

Journal of the American Chemical Society

Volumn 131, Issue 42, 2009, Pages 15246-15250

  Endeward, Burkhard ^a   Butterwick, Joel A ^b   MacKinnon, Roderick ^b   Prisner, Thomas F ^a  

^a GOETHE UNIVERSITY   (Germany)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CENTRAL CHANNELS; DATA SUPPORT; HIGH QUALITY; LABELED PROTEINS; MAGNETIC FIELD STRENGTHS; METHANETHIOSULFONATE; NITROXIDES; OSCILLATION FREQUENCY; POTASSIUM ION CHANNELS; PROBE FREQUENCY; PULSED ELECTRON; QUANTITATIVE SIMULATION; SOLUBLE PROTEINS; TETRAMERS; TETRAMETHYL; TRANSVERSE SPIN RELAXATION; VARIABLE PROBES;

DETERGENTS; ELECTRON SOURCES; ELECTRONS; LABELS; MAGNETIC FIELDS; NITROGEN OXIDES; PROBES; PROTEINS; RESONANCE;

SPIN DYNAMICS;

1 OXYL 2,2,5,5 TETRAMETHYL 3 PYRROLIN 3 YL; DETERGENT; LIPID; MUTANT PROTEIN; NITROXIDE; POTASSIUM CHANNEL; PROTEIN; TETRAMER; THIOMESYLIC ACID METHYL ESTER; UNCLASSIFIED DRUG;

ARTICLE; ELECTRON; ENVIRONMENT; EXPERIMENT; MAGNETIC FIELD; MEMBRANE; ORIENTATION; OSCILLATION; POSITION; QUANTITATIVE ANALYSIS; RELAXATION TIME; SAMPLE; SIMULATION; SPIN LABELING; STRENGTH;

BACTERIA; BACTERIAL PROTEINS; ELECTRON SPIN RESONANCE SPECTROSCOPY; ELECTRONS; MODELS, MOLECULAR; MUTATION; POTASSIUM CHANNELS; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, TERTIARY;

EID: 70350313495     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja904808n     Document Type: Article

References (23)

1. Schiemann, O.; Prisner, T. F. Q. Rev. Biophys. 2007, 40, 1-53.
2. Jeschke, G. Macromol. Rapid Commun. 2002, 23, 227-246.
3. Milov, A.; Salikov, K.; Shirov, M. Fiz. Tverd. Tela (S.-Peterburg) 1981, 23, 975.
4. Milov, A.; Ponomarev, A.; Tsvetkov, Y. Chem. Phys. Lett. 1984, 110, 67-72.
5. Hubbell, W.; Cafiso, D.; Altenbach, C. Nat. Struct. Biol. 2000, 7, 735-739.
6. Sen, K.; Logan, T.; Fajer, P. Biochemistry 2007, 46, 11639-11649.
7. Columbus, L.; Kalai, T.; Jeko, J.; Hideg, K.; Hubbell, W. L. Biochemistry 2001, 40, 3828-3846.
8. Jeschke, G.; Chechik, V.; Ionita, P.; Godt, A.; Zimmermann, H.; Banham, J.; Timmel, C.; Hilger, D.; Jung, H. Appl. Magn. Reson. 2006, 30, 473-498.
9. Chiang, Y. W.; Borbat, P. P.; Freed, J. H. J. Magn. Reson. 2005, 172, 279-295.
10. Margraf, D.; Bode, B.; Marko, A.; Schiemann, O.; Prisner, T. Mol. Phys. 2007, 105, 2153-2160.
11. Marko, A.; Margraf, D.; Yu, H.; Mu, Y.; Stock, G.; Prisner, T. J. Chem. Phys. 2009, 130, 064102.
12. Denysenkov, V.; Prisner, T.; Stubbe, J.; Bennati, M. Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 13386-13390.
13. Weber, A.; Schiemann, O.; Bode, B.; Prisner, T. J. Magn. Reson. 2002, 157, 277-285.
14. Godt, A.; Schulte, M.; Zimmermann, H.; Jeschke, G. Angew. Chem., Int. Ed. 2006, 45, 7560-7564.
15. Polyhach, Y.; Godt, A.; Bauer, C.; Jeschke, G. J. Magn. Reson. 2007, 185, 118-129.
16. Sezer, D.; Freed, J. H.; Roux, B. J. Am. Chem. Soc. 2009, 131, 2597-2605.
17. Guo, Z.; Cascio, D.; Hideg, K.; Hubbell, W. L. Protein Sci. 2008, 17, 228-239.
18. Doyle, D. A.; Morais-Cabral, J.; Pfuetzner, R. A.; Kuo, A.; Gulbis, J. M.; Cohen, S. L.; Chait, B. T.; MacKinnon, R. Science 1998, 280, 69-77.
19. Heginbotham, L.; LeMasurier, M.; Kolmakova-Partensky, L.; Miller, C. J. Gen. Physiol. 1999, 14, 551-560
20. Pannier, M.; Veit, S.; Godt, A.; Jeschke, G.; Spieß, H. W. J. Magn. Reson. 2000, 142, 331-340.
21. Zhou, Y.; Morais-Cabral, J. H.; Kaufman, A.; MacKinnon, R. Nature 2001, 414, 43.
22. Cordero-Morales, J. F.; Cuello, L. G.; Zhao, Y.; Jogini, V.; Cortes, D. M.; Roux, B.; Perozo, E. Nat. Struct. Mol. Biol. 2006, 13, 311-318.
23. Xu, Q.; Ellena, J. F.; Kim, M.; Cafiso, D. S. Biochemistry 2006, 45, 10847-10854.