Pharmacological inhibition of transforming growth factor β signaling decreases infection and prevents heart damage in acute Chagas' disease

Antimicrobial Agents and Chemotherapy

Volumn 53, Issue 11, 2009, Pages 4694-4701

  Waghabi, Mariana C ^a   De Souza, Elen M ^a   De Oliveira, Gabriel M ^a   Keramidas, Michelle ^b,c   Feige, Jean Jacques ^b,c   Araújo Jorge, Tania C ^a   Bailly, Sabine ^b,c  

^a INSTITUTO OSWALDO CRUZ   (Brazil)

^b INSERM   (France)

^c CEA GRENOBLE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

4 [4 (1,3 BENZODIOXOL 5 YL) 5 (2 PYRIDINYL) 1H IMIDAZOL 2 YL]BENZAMIDE; ASPARTATE AMINOTRANSFERASE; CREATINE KINASE; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BRADYCARDIA; CHAGAS DISEASE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DISEASE COURSE; DRUG POTENCY; HEART INJURY; HEART MUSCLE CONDUCTION SYSTEM; HEART PROTECTION; INFLAMMATORY INFILTRATE; MALE; MORTALITY; MOUSE; NONHUMAN; PHARMACOLOGICAL BLOCKING; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TRYPANOSOMA CRUZI;

ANIMALS; BENZAMIDES; BRADYCARDIA; CHAGAS CARDIOMYOPATHY; CHAGAS DISEASE; DIOXOLES; MALE; MICE; MYOCARDIUM; PARASITEMIA; PROTEIN-SERINE-THREONINE KINASES; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; SIGNAL TRANSDUCTION;

EID: 70350307193     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00580-09     Document Type: Article

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