Klebsiella pneumoniae producing CTX-M-15 genes from neonatal intensive care unit in Saudi Arabia

Research Journal of Microbiology

Volumn 4, Issue 7, 2009, Pages 278-285

  Al Agamy, M H M ^a   Shibl, A M ^a   Tawfik, A F ^a   Elbannai, A R ^b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b Qatif Hospital   (Saudi Arabia)

Author keywords

Antibiotic resistance; CTX M 15 genes; ES L; Klebsiella pneumoniae; Saudi Arabia

Indexed keywords

KLEBSIELLA PNEUMONIAE;

EID: 70350306244     PISSN: 18164935     EISSN: None     Source Type: Journal    
DOI: 10.3923/jm.2009.278.285     Document Type: Article

References (30)

1. Abbassi, M.S., C. Torres, W. Achour, L. Vinué and Y. Sáenz et al., 2006q. Genetic characterization of CTX-M-15-producing Klebsiella pneumoniae and Escherichia coli strains isolated from stem cell transplant patients in Tunisia. Int. J. Antimicrob. Agents, 32: 308-314.
2. Al-Agamy, M.H.M., MS-E. Ashour and I. Wiegand, 2006. First description of CTX-M β-lactamase-producing clinical Escherichia coli isolates from Egypt. Inter. J. Antimicrob. Agents, 27: 545-548.
3. Al-Obeid, S., S. Bremont, L. Jabri, N. Massoudi and Q. Haddad, 2008. Klebsiella pneumoniae LO10 producing extended-spectrum beta-lactamase SHV-12 in Saudi Arabia. J. Chemother., 20: 709-713.
4. Baraniak, A., J. Fiett, W. Hryniewicz, P. Nordmann and M. Gniadkowski, 2002. Ceftazidime-hydrolyzing CTX-M-15 extended-spectrum beta-lactamase (ESBL) in Poland. J. Antimicrob. Chemother., 50: 393-396.
5. Bonnet, R., C. Dutour, J.L.M. Sampaio, C. Chanal and D. Sirot et al., 2001. Novel cefotaximase (CTX-M-16) with increased catalytic efficiency due to substitution Asp-240 Gly. Antimicrob. Agents. Chemother., 45: 2269-2275.
6. Canton, R. and T.M. Coque, 2006. The CTX-M β-lactamase pandemic. Curr. Opin. Microbiol., 9: 466-475.
7. Carrër, A., L. Lassel, N. Fortineau, M. Mansouri, N. Anguel, C. Richard and P. Nordmann, 2009. Outbreak of CTX-M-15-Producing Klebsiella pneumoniae in the Intensive Care Unit of a French Hospital. Microb. Drug Resist., 15: 47-54.
8. Chanawong, A., F.M. M'Zali, J. Heritage, J.H. Xiong and P.M. Hawkey, 2002. Three cefotaximases, CTX-M-9, CTX-M-13 and CTX-M-14, among enterobactericeae in the Peoples Rebublic of China. Antimicrob Agents Chemother., 46: 630-637.
9. Clinical Laboratory Standards Institute, 2006. Methods for Dilution Antimicrobial Susceptibility Tests for Bacteria That Grow Aerobically: Approved Standard. 7th Edn., Clinical and Laboratory Standards Institute, Wayne, PA., USA., ISBN: 1-56238-587-9.
10. Conceição, T., A. Brízio, A. Duarte, L.M. Lito, J.M. Cristino and M.J. Salgado, 2005. First Description of CTX-M-15-Producing Klebsiella pneumoniae in Portugal. Antimicrob. Agents Chemother., 49: 477-478.
11. Coque, T.M., A. Oliver, J.C. Pérez-Diaz, F. Baquero and R. Canton, 2002. Genes encoding TEM-4, SHV-2 and CTX-M-10 extended-spectrum β-lactamases are carried by multiple Klebsiella pneumoniae clones in a single hospital (Madrid, 1989 to 2000). Antimicrob. Agents Chemother., 46: 500-510.
12. De-Oliveira D., Y. Doi, D. Szabo, J.M. Adams-Haduch and T.M. Vaz et al., 2008. Multiclonal outbreak of Klebsiella pneumoniae producing extended-spectrum beta-lactamase CTX-M-2 and novel variant CTX-M-59 in a neonatal intensive care unit in Brazil. Antimicrob Agents Chemother. 52: 1790-1793.
13. Ensor, V.M., W. Jamal, V.O. Rotimi, J.T. Evans and P.M. Hawkey, 2009. Predominance of CTX-M-15 extended spectrum beta-lactamases in diverse Escherichia coli and Klebsiella pneumoniae from hospital and community patients in Kuwait. Int. J. Antimicrob. Agents, 33: 487-489.
14. Hobson, R.P., F.M. MacKenzie and I.M. Gould, 1996. An outbreak of multiply-resistant Klebsiella pneumoniae in the Grampian region of Scotland. J. Hosp. Infect., 33: 249-249.
15. Karim, A., L. Poirel, S. Nagarajan and P. Nordmann, 2001. Plasmid-mediated extended-spectrum β-lactamase (CTX-M-3 like) from India and gene association with insertion sequence ISEcp1. FEMS Microbiol. Lett., 201: 237-241.
16. Kliebe, C., B.A. Nies, S.F. Meyer, R.M. Tolxdorff-Neutzling and B. Wiedeman, 1985. Evolution of plasmid-coded resistance to broad-spectrum cephalosporin. Antimicrob. Agents Chemother., 28: 302-307.
17. Livermore, D.M. and N. Woodford, 2007. The beta-lactamase threat in Enterobacteriaceae, Pseudomonas and Acinetobacter. Trends Microbiol., 14: 413-420.
18. Livermore, D.M., R. Canton, M. Gniadkowski, P. Nordmann, G.M. Rossolini and G. Arlet, 2007. CTX-M: Changing the face of ESBLs in Europe. J. Antimicrob. Chemother., 59: 165-174.
19. Nordmann, P. and L. Poirel, 2002. Emerging carbapenemases in gram negative aerobes. Clin. Microbiol. Infect., 8: 321-331.
20. Nukaga, M., K. Mayama, A.M. Hujer, R.A. Bonomo and J.R. Knox, 2003. Ultrahigh resolution structure of a class A β-lactamase: On the mechanism and specificity of the extended-spectrum SHV-2 enzyme. J. Mol. Biol., 328: 289-301.
21. Nüesch-Inderbinen, M.T., F.H. Kayser and H. Hachler, 1997. Survey and molecular genetics of SHV-lactamases in Enterobacteriaceae in Switzerland: two novel enzymes, SHV-11 and SHV-12. Antimicrob. Agents Chemother., 41: 943-949.
22. Poirel, L., C. Heritier, V. Tolun and P. Nordmann, 2004. Emergence of oxacillinase-mediated resistance to imipenem in Klebsiella pneumoniae. Antimicrob. Agents Chemother., 48: 15-22.
23. Quale, J.M., D. Landman, P.A. Bradford, M. Visalli and J. Ravishankar et al., 2002. Molecular epidemiology of a citywide outbreak of extended-spectrum beta-lactamase-producing Klebsiella pneumoniae infection. Clin. Infect. Dis., 35: 834-841.
24. Randrianirina, F., S. Vedy, D. Rakotovao, C.E. Ramarokoto and H. Ratsitohaina et al., 2009. Role of contaminated aspiration tubes in nosocomial outbreak of Klebsiella pneumoniae producing SHV-2 and CTX-M-15 extended-spectrum beta-lactamases. J. Hosp. Infect., 72: 23-29.
25. Rebuck, J.A., K.M. Olsen, P.D. Fey, A.N. Langnas and M.E. Rupp, 2000. Characterization of an outbreak due to extended-spectrum beta-lactamase producing Klebsiella pneumoniae in a paediatric intensive care unit transplant population. Clin. Infect. Dis., 31: 1368-1372.
26. Sanger, F., S. Nicklen and A.R. Coulson, 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA., 74: 5463-5467.
27. Soge, O.O., A.M. Queenan, K.K. Ojo, B.A. Adeniyi and M.C. Roberts, 2006. CTX-M-15 extended-spectrum β-lactamases from Nigerian Klebsiella pneumoniae. J. Antimicrob. Chemother., 57: 24-30.
28. Vatopoulos, A.C., A. Philippon and L.S. Tzouvelekis, 1990. Prevalence of SHV-5 type β-lactamase in clinical isolates of Klebsiella pneumoniae and Escherichia coli in Greece. J. Antimicrob. Chemother., 26: 2755-2759.
29. Villegas, M.V., A. Correa, F. Perez, M.C. Miranda and T. Zuluaga et al., 2004. Prevalence and characterization of extended-spectrum beta-lactamases in Klebsiella pneumoniae and Escherichia coli isolates from Colombian hospitals. Diagn. Microbiol. Infect. Dis., 49: 217-222.
30. Yigit, H., A.M. Queenan, G.J. Anderson, A. Domenech-Sanchez and J.W. Biddle et al., 2001. Novel carbapenem-hydrolyzing beta-lactamase, KPC-1, from a carbapenem-resistant strain of Klebsiella pneumoniae. Antimicrob. Agents Chemother., 45: 1151-1161.