Synthesis and Na+/H+ exchanger-1 inhibitory activity of substituted (quinolinecarbonyl)guanidine derivatives

Chemistry and Biodiversity

Volumn 6, Issue 10, 2009, Pages 1727-1736

  Mao, Dan ^a   Xu, Yungen ^a   Hu, Xiaoping ^a   Zhang, Guomin ^a   Dong, Jin ^a   Gong, Guoqing ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

(QUINOLINECARBONYL)GUANIDINE DERIVATIVE; 1 [4 (PROPYLAMINO) 6 [[4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL]METHYL]QUINOLINE 3 CARBONYL]GUANIDINE; 1 [4 [(3,5 DIMETHYLPHENYL)AMINO] 6 [[4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL]METHYL]QUINOLINE 3 CARBONYL]GUANIDINE; 1 [4 [(4 ETHOXYPHENYL)AMINO] 6 [[4 (2,3,4 TRIMETHOXYBENZYL)PIPERAZIN 1 YL]METHYL]QUINOLINE 3 CARBONYL]GUANIDINE; CARIPORIDE; GUANIDINE DERIVATIVE; QUINOLINE DERIVATIVE; SODIUM PROTON EXCHANGE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION RESPONSE; DRUG DESIGN; DRUG EFFICACY; DRUG POTENCY; DRUG SYNTHESIS; HEART MUSCLE ISCHEMIA; HEART PROTECTION; NONHUMAN; RAT; REACTION ANALYSIS; REPERFUSION INJURY;

ANIMALS; BLOOD PLATELETS; CARDIOTONIC AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; GUANIDINES; HYDROGEN-ION CONCENTRATION; QUINOLINES; RATS; RATS, SPRAGUE-DAWLEY; REPERFUSION INJURY; SODIUM-HYDROGEN ANTIPORTER; SULFONES;

MAMMALIA; RATTUS;

EID: 70350255503     PISSN: 16121872     EISSN: 16121880     Source Type: Journal    
DOI: 10.1002/cbdv.200800268     Document Type: Article

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