Genome-Wide Association Study in Esophageal Squamous Cell Carcinoma

Gastroenterology

Volumn 137, Issue 5, 2009, Pages 1573-1576

  Bass, Adam J ^a   Meyerson, Matthew ^a  

^a DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE DEHYDROGENASE ISOENZYME 2;

ADH1B GENE; ALCOHOL CONSUMPTION; ALLELE; BRAP GENE; CANCER RISK; CANCER SUSCEPTIBILITY; CIGARETTE SMOKING; EDITORIAL; ENVIRONMENTAL FACTOR; ESOPHAGEAL SQUAMOUS CELL CARCINOMA; GENE LOCUS; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC DISORDER; GENETIC IDENTIFICATION; GENETIC RISK; GENETIC VARIABILITY; GENOMICS; GENOTYPE; HUMAN; HUMAN GENOME; MUTATOR GENE; ONCOGENE MYC; PREVALENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SOCIOECONOMICS;

ALCOHOL DEHYDROGENASE; ALDEHYDE DEHYDROGENASE; CARCINOMA, SQUAMOUS CELL; ESOPHAGEAL NEOPLASMS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; POLYMORPHISM, SINGLE NUCLEOTIDE; RISK FACTORS;

EID: 70350241385     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.gastro.2009.09.026     Document Type: Editorial

References (21)

1. Kinzler K.W., Nilbert M.C., Su L.K., et al. Identification of FAP locus genes from chromosome 5q21. Science 253 (1991) 661-665
2. Liaw D., Marsh D.J., Li J., et al. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome. Nat Genet 1 (1997) 64-67
3. Malkin D., Li F.P., Strong L.C., et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas and other neoplasms. Science 250 (1990) 12333-12338
4. Schubbert S., Zenker M., Rowe S.L., et al. Germline KRAS mutations cause Noonan syndrome. Nat Genet 3 (2006) 331-336
5. Altshuler D., Daly M.J., and Lander E.S. Genetic mapping in human disease. Science 322 (2008) 881-888
6. Zanke B.W., Greenwood C.M., Rangrej J., et al. Genome-wide association scan identifies a colorectal cancer susceptibility locus on chromosome 8q24. Nat Genet 39 (2007) 989-994
7. Tomlinson I., Webb E., Carvajal-Carmona L., et al. A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21. Nat Genet 39 (2007) 984-988
8. Tenesa A., Farrington S.M., Prendergast J.G.D., et al. Genome-wide association scan identifies a colon cancer susceptibility locus on 11q23 and replicates loci at 8q24 and 18q21. Nat Genet 40 (2008) 631-637
9. Haiman C.A., Marchand L.L., Yamamato J., et al. A common genetic risk factor for colorectal and prostate cancer. Nat Genet 39 (2007) 954-956
10. Broderick P., Carvajal-Carmona L., Pittman A.M., et al. A genome-wide association study shows that common alleles of SMAD7 influence colorectal cancer risk. Nat Genet 39 (2007) 1315-1317
11. Tomlinson I., Webb E., Carvajal-Carmona, et al. A genome-wide association study identified colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3. Nat Genet 40 (2008) 623-630
12. Amundadottir L., Kraft P., Stolzenberg-Soloman R.Z., et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet 41 (2009) 986-990
13. Pomerantz M.M., Ahmadiyeh N., Jia L., et al. The 8q24 cancer risk variant rs6983267 shows long-range interaction with MYC in colorectal cancer. Nat Genet 41 (2009) 882-884
14. Tuupanen S., Turunen M., Lehtonen R., et al. The common colorectal cancer predisposition SNP rs6983267 at chromosome 8q24 confers potential to enhance Wnt signaling. Nat Genet 41 (2009) 885-890
15. Cheung W.Y., and Liu G. Genetic variations in esophageal cancer risk and prognosis. Gastroenterol Clin North Am 38 (2009) 75-91
16. Hiyama T., Toshihara M., Tanaka S., et al. Genetic polymorphisms and esophageal cancer risk. Int J Cancer 121 (2007) 1643-1658
17. Pandeya N., Williams G., Green A.C., et al. Alcohol consumption and the risks of adenocarcinoma and squamous cell carcinoma of the esophagus. Gastroenterology 136 (2009) 1215-1224
18. Cui R., Kamatani Y., Takahashi A., et al. Functional variants in ADH1B and ALDH2 coupled with alcohol and smoking synergistically enhance esophageal cancer risk. Gastroenterology 137 (2009) 1768-1775
19. Hori H., Kawano T., Endo M., et al. Genetic polymorphisms of tobacco-and alcohol-related metabolizing enzymes and human esophageal squamous cell carcinoma susceptibility. J Clin Gastro 25 (1997) 568-575
20. Yokoyama A., Kato H., Yokoyama T., et al. Genetic polymorphisms of alcohol and aldehyde dehydrenases and glutathione S-transferase M1 and drinking, smoking, and diet in Japanese men with esophageal squamous cell carcinoma. Carcinogenesis 23 (2002) 1851-1859
21. Lee C.H., Lee JM Wu D.C., et al. Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard to the consumption of alcohol, tobacco and betel quid. Int J Cancer 122 (2008) 1347-1356