Reductive activation of mitomycin C by thiols: Kinetics, mechanism, and biological implications

Chemical Research in Toxicology

Volumn 22, Issue 10, 2009, Pages 1663-1668

  Paz, Manuel M ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

MITOMYCIN C; THIOL;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVATION; DRUG EFFECT; DRUG MECHANISM; DRUG METABOLISM; DRUG STRUCTURE; PH;

ANTIBIOTICS, ANTINEOPLASTIC; DNA ADDUCTS; HYDROGEN-ION CONCENTRATION; KINETICS; MITOMYCIN; NAD(P)H DEHYDROGENASE (QUINONE); NADPH-FERRIHEMOPROTEIN REDUCTASE; OXIDATION-REDUCTION; SULFHYDRYL COMPOUNDS;

EID: 70350239993     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx9002758     Document Type: Article

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