Reductive activation of mitomycin A by thiols

Organic Letters

Volumn 3, Issue 18, 2001, Pages 2789-2792

  Paz, Manuel M ^a,b   Tomasz, Maria ^a  

^a CITY UNIVERSITY OF NEW YORK   (United States)

^b Facultade de Ciencias   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

METHANOL; MITOMYCIN; MITOMYCIN A; THIOL DERIVATIVE;

ARTICLE; CHEMISTRY; OXIDATION REDUCTION REACTION;

METHANOL; MITOMYCINS; OXIDATION-REDUCTION; SULFHYDRYL COMPOUNDS;

EID: 0035818011     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol015517+     Document Type: Article

References (17)

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14. Adduct 9 (C-7 thiol adduct) is the most likely regioisomer of six possible quinone adducts, all of which could react by the same mechanism.
15. 6b Furthermore, it would not explain the large rate increase observed with DTT.
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17. obs on thiol concentration is essentially identical in the three thiols (Table 1).