ChilDrive: A technique of combining regional cutaneous hypothermia with iontophoresis for the delivery of drugs to synovial fluid

Pharmaceutical Research

Volumn 26, Issue 11, 2009, Pages 2535-2540

  Sammeta, Srinivasa M ^a   Murthy, S Narasimha ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

Author keywords

Intraarticular microdialysis; Iontophoresis; Synovial fluid; Targeting; Transdermal

Indexed keywords

DICLOFENAC; PREDNISOLONE SODIUM PHOSPHATE;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; CHILDRIVE TECHNIQUE; CONTROLLED STUDY; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG ELIMINATION; DRUG HALF LIFE; DRUG METABOLISM; DRUG SYNOVIAL FLUID LEVEL; IONTOPHORESIS; KNEE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; SKIN TEMPERATURE; TECHNIQUE; TIME; TIME TO MAXIMUM PLASMA CONCENTRATION;

ADMINISTRATION, CUTANEOUS; ANIMALS; ANTI-INFLAMMATORY AGENTS; BIOLOGICAL AVAILABILITY; DICLOFENAC; DRUG DELIVERY SYSTEMS; HYPOTHERMIA, INDUCED; IONTOPHORESIS; MALE; MODELS, BIOLOGICAL; PREDNISOLONE; RATS; RATS, SPRAGUE-DAWLEY; SYNOVIAL FLUID;

EID: 70350221897     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-009-9977-0     Document Type: Article

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