Innate immune responses of pulmonary epithelial cells to Burkholderia pseudomallei infection

PLoS ONE

Volumn 4, Issue 10, 2009, Pages

  Sim, Siew Hoon ^a   Liu, Yichun ^a   Wang, Dongling ^a   Novem, Vidhya ^a   Sivalingam, Suppiah Paramalingam ^a   Thong, Tuck Weng ^a   Ooi, Eng Eong ^a,b   Tan, Gladys ^a  

^a DSO NATIONAL LABORATORIES   (Singapore)

^b DUKE NUS MEDICAL SCHOOL   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 6; LYSOZYME; MONOCYTE CHEMOTACTIC PROTEIN 1; SECRETORY LEUKOCYTE PROTEINASE INHIBITOR; SURFACTANT PROTEIN A; SURFACTANT PROTEIN D; SYNAPTOPHYSIN; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TUMOR NECROSIS FACTOR ALPHA; CCL2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; BACTERIAL STRAIN; BACTERIUM CULTURE; BAGG ALBINO MOUSE; BURKHOLDERIA INFECTION; BURKHOLDERIA PSEUDOMALLEI; C57BL 6 MOUSE; CELL GROWTH; CELL INVASION; CELL LINE; CONTROLLED STUDY; EPITHELIUM CELL; FEMALE; INNATE IMMUNITY; LUNG ALVEOLUS CELL; MALE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; AEROSOL; ANIMAL; C57BL MOUSE; IMMUNOLOGY; LUNG; METABOLISM; MICROBIOLOGY; MOUSE;

BURKHOLDERIA PSEUDOMALLEI; MURINAE;

AEROSOLS; ANIMALS; BURKHOLDERIA INFECTIONS; BURKHOLDERIA PSEUDOMALLEI; CELL LINE; CHEMOKINE CCL2; EPITHELIAL CELLS; FEMALE; IMMUNITY, INNATE; INTERLEUKIN-6; LUNG; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; TUMOR NECROSIS FACTOR-ALPHA;

EID: 70350215626     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007308     Document Type: Article

References (52)

1. Cheng AC, Currie BJ (2005) Melioidosis: epidemiology, pathophysiology, and management. Clin Microbiol Rev 18: 383-416.
2. Dance DA (2000) Melioidosis as an emerging global problem. Acta Trop 74: 115-119.
3. Dance DA (1991) Melioidosis: the tip of the iceberg? Clin Microbiol Rev 4: 52-60.
4. Boonsawat W, Boonma P, Tangdajahiran T, Paupermpoonsiri S, Wongpratoom W, et al. (1990) Community-acquired pneumonia in adults at Srinagarind Hospital. J Med Assoc Thai 73: 345-352.
5. White NJ (2003) Melioidosis. Lancet 361: 1715-1722.
6. Currie BJ, Jacups SP (2003) Intensity of rainfall and severity of melioidosis, Australia. Emerg Infect Dis 9: 1538-1542.
7. Tan GY, Liu Y, Sivalingam SP, Sim SH, Wang D, et al. (2008) Burkholderia pseudomallei aerosol infection results in differential inflammatory responses in BALB/c and C57Bl/6 mice. J Med Microbiol 57: 508-515.
8. Currie B, Howard D, Nguyen VT, Withnall K, Merianos A (1993) The 1990-1991 outbreak of melioidosis in the Northern Territory of Australia: clinical aspects. Southeast Asian J Trop Med Public Health 24: 436-443.
9. Potera C (2005) In disaster's wake: tsunami lung. Environ Health Perspect 113: A734.
10. Liu Y, Loh JP, Aw LT, Yap EP, Lee MA, et al. (2006) Rapid molecular typing of Burkholderia pseudomallei, isolated in an outbreak of melioidosis in Singapore in 2004, based on variable-number tandem repeats. Trans R Soc Trop Med Hyg 100: 687-692.
11. Rogan MP, Geraghty P, Greene CM, O'Neill SJ, Taggart CC, et al. (2006) Antimicrobial proteins and polypeptides in pulmonary innate defence. Respir Res 7: 29.
12. Breitbach K, Klocke S, Tschernig T, van Rooijen N, Baumann U, et al. (2006) Role of inducible nitric oxide synthase and NADPH oxidase in early control of Burkholderia pseudomallei infection in mice. Infect Immun 74: 6300-6309.
13. Miyagi K, Kawakami K, Saito A (1997) Role of reactive nitrogen and oxygen intermediates in gamma interferon-stimulated murine macrophage bactericidal activity against Burkholderia pseudomallei. Infect Immun 65: 4108-4113.
14. Popov SF, Kurilov V, Lagutin MP (1992) The interaction of the causative agent of melioidosis with the host's alveolar macrophages. Mikrobiol Zh 54: 3-7.
15. Mendez-Samperio P, Miranda E, Trejo A (2008) Regulation of human beta-defensin 2 by Mycobacterium bovis bacillus Calmette-Guerin (BCG): involvement of PKC, JNK, and PI3K in human lung epithelial cell line (A549). Peptides 29: 1657-1663.
16. O'Brien AD, Standiford TJ, Bucknell KA, Wilcoxen SE, Paine R, 3rd (1999) Role of alveolar epithelial cell intercellular adhesion molecule-1 in host defense against Klebsiella pneumoniae. Am J Physiol 276: L961-970.
17. Yang J, Hooper WC, Phillips DJ, Talkington DF (2002) Regulation of proinflammatory cytokines in human lung epithelial cells infected with Mycoplasma pneumoniae. Infect Immun 70: 3649-3655.
18. Utaisincharoen P, Anuntagool N, Arjcharoen S, Lengwehasatit I, Limposuwan K, et al. (2004) Burkholderia pseudomallei stimulates low interleukin-8 production in the human lung epithelial cell line A549. Clin Exp Immunol 138: 61-65.
19. Simian M, Hirai Y, Navre M, Werb Z, Lochter A, Bissell MJ (2001) The interplay of matrix metalloproteinases, morphogens and growth factors is necessary for branching of mammary epithelial cells. Development 128: 3117-31.
20. Elsinghorst EA (1994) Measurement of invasion by gentamicin resistance. Methods Enzymol 236: 405-420.
21. Giulietti A, Overbergh L, Valckx D, Decallonne B, Bouillon R, et al. (2001) An overview of real-time quantitative PCR: applications to quantify cytokine gene expression. Methods 25: 386-401.
22. Ngauy V, Lemeshev Y, Sadkowski L, Crawford G (2005) Cutaneous melioidosis in a man who was taken as a prisoner of war by the Japanese during World War II. J Clin Microbiol 43: 970-972.
23. Wiersinga WJ, van der Poll T, White NJ, Day NP, Peacock SJ (2006) Melioidosis: insights into the pathogenicity of Burkholderia pseudomallei. Nat Rev Microbiol 4: 272-282.
24. Easton A, Haque A, Chu K, Lukaszewski R, Bancroft GJ (2007) A critical role for neutrophils in resistance to experimental infection with Burkholderia pseudomallei. J Infect Dis 195: 99-107.
25. Utaisincharoen P, Tangthawornchaikul N, Kespichayawattana W, Anuntagool N, Chaisuriya P, et al. (2000) Kinetic studies of the production of nitric oxide (NO) and tumour necrosis factor-alpha (TNF-alpha) in macrophages stimulated with Burkholderia pseudomallei endotoxin. Clin Exp Immunol 122: 324-329.
26. Bals R, Hiemstra PS (2004) Innate immunity in the lung: how epithelial cells fight against respiratory pathogens. Eur Respir J 23: 327-333.
27. Basu S, Fenton MJ (2004) Toll-like receptors: function and roles in lung disease. Am J Physiol Lung Cell Mol Physiol 286: L887-892.
28. Droemann D, Albrecht D, Gerdes J, Ulmer AJ, Branscheid D, et al. (2005) Human lung cancer cells express functionally active Toll-like receptor 9. Respir Res 6: 1.
29. Greene CM, Carroll TP, Smith SG, Taggart CC, Devaney J, et al. (2005) TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells. J Immunol 174: 1638-1646.
30. Hauber HP, Tulic MK, Tsicopoulos A, Wallaert B, Olivenstein R, et al. (2005) Toll-like receptors 4 and 2 expression in the bronchial mucosa of patients with cystic fibrosis. Can Respir J 12: 13-18.
31. Hippenstiel S, Opitz B, Schmeck B, Suttorp N (2006) Lung epithelium as a sentinel and effector system in pneumonia-molecular mechanisms of pathogen recognition and signal transduction. Respir Res 7: 97.
32. Zhang Z, Louboutin JP, Weiner DJ, Goldberg JB, Wilson JM (2005) Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5. Infect Immun 73: 7151-7160.
33. Gentry M, Taormina J, Pyles RB, Yeager L, Kirtley M, et al. (2007) Role of primary human alveolar epithelial cells in host defense against Francisella tularensis infection. Infect Immun 75: 3969-3978.
34. Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, et al. (2007) Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily. Biochem Biophys Res Commun 357: 977-983.
35. Barnes JL, Ulett GC, Ketheesan N, Clair T, Summers PM, et al. (2001) Induction of multiple chemokine and colony-stimulating factor genes in experimental Burkholderia pseudomallei infection. Immunol Cell Biol 79: 490-501.
36. Friedland JS, Suputtamongkol Y, Remick DG, Chaowagul W, Strieter RM, et al. (1992) Prolonged elevation of interleukin-8 and interleukin-6 concentrations in plasma and of leukocyte interleukin-8 mRNA levels during septicemic and localized Pseudomonas pseudomallei infection. Infect Immun 60: 2402-2408.
37. Simpson AJ, Smith MD, Weverling GJ, Suputtamongkol Y, Angus BJ, et al. (2000) Prognostic value of cytokine concentrations (tumor necrosis factor-alpha, interleukin-6, and interleukin-10) and clinical parameters in severe melioidosis. J Infect Dis 181: 621-625.
38. Sitaraman SV, Merlin D, Wang L, Wong M, Gewirtz AT, et al. (2001) Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6. J Clin Invest 107: 861-869.
39. Baier J, Kruger TE (2000) Induction of monocyte chemoattractant protein-1 by Mycoplasma hominis in respiratory epithelial cells. J Investig Med 48: 457-464.
40. Jia T, Serbina NV, Brandl K, Zhong MX, Leiner IM, et al. (2008) Additive roles for MCP-1 and MCP-3 in CCR2-mediated recruitment of inflammatory monocytes during Listeria monocytogenes infection. J Immunol 180: 6846-6853.
41. Fahlgren A, Hammarstrom S, Danielsson A, Hammarstrom ML (2003) Increased expression of antimicrobial peptides and lysozyme in colonic epithelial cells of patients with ulcerative colitis. Clin Exp Immunol 131: 90-101.
42. Reviglio VE, Sambuelli RH, Olmedo A, Falco M, Echenique J, et al. (2007) Secretory leukocyte protease inhibitor is an inducible antimicrobial peptide expressed in Staphylococcus aureus endophthalmitis. Mediators Inflamm 2007: 93857.
43. Schutyser E, Struyf S, Van Damme J (2003) The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev 14: 409-426.
44. Wu YY, Tsai HF, Lin WC, Hsu PI, Shun CT, et al. (2007) Upregulation of CCL20 and recruitment of CCR6+ gastric infiltrating lymphocytes in Helicobacter pylori gastritis. Infect Immun 75: 4357-4363.
45. Hoover DM, Boulegue C, Yang D, Oppenheim JJ, Tucker K, et al. (2002) The structure of human macrophage inflammatory protein-3alpha/CCL20. Linking antimicrobial and CC chemokine receptor-6-binding activities with human beta-defensins. J Biol Chem 277: 37647-37654.
46. Weldon S, Taggart CC (2007) Innate host defense functions of secretory leucoprotease inhibitor. Exp Lung Res 33: 485-491.
47. Abe T, Tominaga Y, Kikuchi T, Watanabe A, Satoh K, et al. (1997) Bacterial pneumonia causes augmented expression of the secretory leukoprotease inhibitor gene in the murine lung. Am J Respir Crit Care Med 156: 1235-1240.
48. Akinbi HT, Epaud R, Bhatt H, Weaver TE (2000) Bacterial killing is enhanced by expression of lysozyme in the lungs of transgenic mice. J Immunol 165: 5760-5766.
49. Islam D, Bandholtz L, Nilsson J, Wigzell H, Christensson B, et al. (2001) Downregulation of bactericidal peptides in enteric infections: a novel immune escape mechanism with bacterial DNA as a potential regulator. Nat Med 7: 180-185.
50. Sperandio B, Regnault B, Guo J, Zhang Z, Stanley SL, Jr., et al. (2008) Virulent Shigella flexneri subverts the host innate immune response through manipulation of antimicrobial peptide gene expression. J Exp Med 205: 1121-1132.
51. Tomimori K, Uema E, Teruya H, Ishikawa C, Okudaira T, et al. (2007) Helicobacter pylori induces CCL20 expression. Infect Immun 75: 5223-5232.
52. Choi SC, Choi EJ, Oh HM, Lee S, Lee JK, et al. (2006) DA-9601, a standardized extract of Artemisia asiatica, blocks TNF-alpha-induced IL-8 and CCL20 production by inhibiting p38 kinase and NF-kappaB pathways in human gastric epithelial cells. World J Gastroenterol 12: 4850-4858.