The protective effects of carrot seed extract on spermatogenesis and cauda epididymal sperm reserves in gentamicin treated rats

Yakhteh

Volumn 11, Issue 3, 2009, Pages 327-333

  Nouri, Mohammad ^a   Khaki, Arash ^b   Azar, Fatemeh Fathi ^c   Rashidi, Mohammad Reza ^d  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISLAMIC AZAD UNIVERSITY   (Iran)

^c TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Carrot seed extract; Gentamicin; Gonadotrophin; Spermatogenesis

Indexed keywords

DAUCUS CAROTA EXTRACT; FOLLITROPIN; GENTAMICIN; LUTEINIZING HORMONE; PLANT EXTRACT; SEX HORMONE; TESTOSTERONE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CARROT; CONTROLLED STUDY; DRUG EFFECT; DRUG MEGADOSE; EPIDIDYMIS TAIL; FOLLITROPIN BLOOD LEVEL; HISTOPATHOLOGY; LOW DRUG DOSE; LUTEINIZING HORMONE BLOOD LEVEL; MALE; NECROSIS; NONHUMAN; PLANT SEED; RAT; SPERMATOGENESIS; SPERMATOZOON COUNT; SPERMATOZOON MOTILITY; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL;

EID: 70350191799     PISSN: 15614921     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Kirtikar KR, Basu BD. Indian medianal plants. 2nd ed. New Delhi: Periodical Export; 1991: 195-206.
2. Bishayee A, Sarkar A, Chatterjee M. Hepatoprotective activity of carrot (Daucus carota L.) against carbon tetrachloride intoxication in mouse liver. J Ethnopharmacol. 1995; 47: 69-74.
3. Jasicka-Misiak I, Wieczorek PP, Kafarski P. Crotonic add as a bioactive factor in carrot seeds (Daucus carota L.). Phytochemistry. 2005; 66: 1485-1491.
4. Spence JD. Fasting lipids: the carrot in the snowman. Can J Cardid. 2003; 19: 890-892.
5. Balasubramaniam P, Pari L, Menon VP. Protective effect of carrot (Daucus carota L.) against lindane - induced hepatotoxicity in rats. Phytother Res. 1998; 12: 434-436.
6. Mahran GH, Kadry HA, Isaac ZG, Jhabet CT, Al-Azizi M, El-Oiemy M. Investigation of diuretic drug plants. 1. Phytochemical screening and pharmacological evaluation of Anethum graveolens L, Apium graveolens L, Daucus carota L. and Eruca sativa mill. Phytother Res. 1991; 5: 169-172.
7. Vasudevan M, Parle M. Pharmacological Evidence for the Potential of Daucus carota in the Management of Cognitive Dysfunctions. Biol Pharm Bull. 2006; 29: 1154-1161.
8. Jasicka-Misiak I, Wieczorek PP, Kafarski P. Crotonic add as a bioactive factor in carrot seeds (Daucus carota L.). Phytochemistry. 2005; 66: 1485-1491.
9. Majumder PK, Dasgupta S, Mukhopadhaya RK, Mazumdar UK, Gupta M. Anti-steroidogenic activity of the petroleum ether extract and fraction 5 (fatty acids) of carrot (Daucus carota L.) seeds in mouse ovary. J Ethnopharmacol. 1997; 57: 209-212.
10. Keenan DL, Dharmarajan AM, Zacur HA. Dietary carrot results in diminished ovarian progesterone secretion, whereas a metabolite, retinoic add, stimulates progesterone secretion in the in vitro perfused rabbit ovary. Fertil Steril. 1997; 68: 358-363.
11. Jorjani SE. Zhakhireh Kharazmshahi. Tehran: Iranian Cultural Organisation Press; 1976; 87-89.
12. Wang RS, Ohtani K, Suda M, Nakajima T. Inhibitory effect of ethylene glycol monoethyl ether on rat sperm motion. Ind Health. 2006; 44: 665-668.
13. Amann RP, Almquist JO. Reprodudive Capacity of Dairy Bulls. I. Technique for Direct Measurement of Gonadal and Extra-Gonadal Sperm Reserves. J Dairy Sci. 1961; 44: 1537-1545.
14. Obidike IR, Maduabuchi IU, Olumuyiwa SS. Testicular morphology and cauda epididymal sperm reserves of male rats exposed to Nigerian Qua Iboe Brent crude oil. J Vet Sci. 2007; 8: 1-5.
15. Halliwell B, Gutteridge JMC, Cross CE. Free radicals, antioxidants, and human disease: where are we now? J Lab Clin Med. 1992; 119: 598-620.
16. Suryavathi V, Sharma S, Sharma S, Saxena P, Pandey S, Graver R, et al. Acute toxicity of textile dye wastewaters (untreated and treated) of Sanganer on male reproductive systems of albino rats and mice. Reprod Toxicol. 2005; 19: 547-556.
17. Reddy PS, Pushpalatha T, Reddy PS. Reduction of spermatogenesis and steroidogenesis in mice after fentin and fenbutatin administration. Toxicol Lett 2006; 166: 53-59.
18. Huynh PN, Hikim AP, Wang C, Stefonovic K, Lue YH, Leung A, et al. J Androl. 2000; 21: 689-699.
19. Hew KW, Heath GL, Jiwa AH, Welsh MJ. Cadmium in vivo causes disruption of tight jundion-assodated microfilaments in rat sertoli cells. Biol Reprod. 1993; 49: 840-849.
20. Acharya UR, Mishra M, Patro J, Panda MK. Effect of vitamins C and E on spermatogenesis in mice exposed to cadmium. Reprod Toxicol. 2008; 25: 84-88.
21. Yousef MI. Protective role of ascorbic add to enhance reproductive performance of male rabbits treated with stannous chloride. Toxicology. 2005; 207: 81-89.
22. Dawson EB, Harris WA, Teter MC, Powell LC. Effect of ascorbic acid supplementation on the sperm quality of smokers. Fertil Steril. 1992; 58: 1034-1039.
23. Yu LL, Zhou KK, Parry J. Antioxidant properties of cold-pressed black caraway, carrot, cranberry, and hemp seed oils. Food Chem. 2005; 91: 723-729.
24. Timmermans LM. Modifications in spermatogenesis following antibiotic therapy. Acta Urol Belg. 1989; 57: 35-46.
25. Bestes A, Bayar MK, Akpolat N, Okuducu MN. Effect of sevoflurane anesthesia on the severity of renal histopathologic changes in rabbits pretreated with gentamicin: A controlled, investigator-blinded, experimental study. Curr Therapeutic Res. 2006; 67: 386-395.
26. Polat A, Parlakpinar H, Tasdemir S, Colak C, Vardi N, Ucar M, et al. Protective role of aminoguanidine on gentamicin-induced acute renal failure in rats. Acta Histochemica. 2006; 108: 365-371.
27. Hong SH, Park SK, Cho Y, Lee H, Kim KR, Kim MG, et al. Gentamidn induced nitric oxide-related oxidative damages on vestibular afferents in the guinea pig. Hearing Res. 2006; 211: 46-53.
28. Ademuyiwa O, Ngaha EO, Ubah FO. Vitamin E and selenium in gentamicin nephrotoxicity. Toxicology. 1990; 9: 281-288.
29. Anahara R, Toyama Y, Mori C. Review of the histological effects of the anti-androgen, flutamide, on mouse testis. Reprod Toxicol. 2008; 25: 139-43.