Detection of promoter hypermethylation of the CpG island of E-cadherin in gastric cardiac adenocarcinoma

European Journal of Medical Research

Volumn 14, Issue 10, 2009, Pages 453-458

  Guo, W ^a   Dong, Zhiming ^a   Guo, Y ^a   Kuang, G ^a   Yang, Z ^a   Chen, Z ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

Author keywords

E cadherin; Gastric cardiac adenocarcinoma; Methylation

Indexed keywords

MESSENGER RNA; UVOMORULIN;

ADULT; AGED; ARTICLE; CANCER STAGING; CARDIA CARCINOMA; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; FEMALE; GENE EXPRESSION; GENE SILENCING; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PROMOTER REGION; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE;

EID: 70350113452     PISSN: 09492321     EISSN: None     Source Type: Journal    
DOI: 10.1186/2047-783x-14-10-453     Document Type: Article

References (28)

1. Takeichi M. Morphogenetic roles of classic cadherins. Curr Opin Cell Biol. 1995; 7: 619-627.
2. Grunwald GB. The structural and functional analysis of cadherin calcium-dependent cell adhesion molecules. Curr Opin Cell Biol. 1993; 5:797-805. (Pubitemid 223002750)
3. Hirohashi S. Inactivation of the E-cadherin-mediated cell adhesion system in human cancers. AmJ Pathol. 1998; 153:333-339. (Pubitemid 28373643)
4. Levenberg S, Yarden A, Kam Z, et al. p27 is involved in N-cadherin-mediated contact inhibition of cell growth and S-phase entry. Oncogene. 1999; 18, 869-876. (Pubitemid 29086263)
5. Wijnhoven BP, Pignatelli M. E-cadherin-catenin: more than a "sticky" molecular complex. Lancet. 1999; 354: 356-357.
6. Katagiri A, Watanabe R, Tomita Y. E-cadherin expression in renal cell cancer and its significance in metastasis and survival. Br J Cancer. 1995; 71: 376-379.
7. Gayther SA, Gorringe KL, Ramus SJ, et al. Identification of germ-line E-cadherin mutations in gastric cancer families of European origin. Cancer Res. 1998; 58:4086-4089
8. Richards FM, McKee SA, Rajpar MH, et al. Germline E-cadherin gene (CDH1) mutations predispose to familial gastric cancer and colorectal cancer. Hum Mol Genet. 1999; 8: 607-610.
9. Becker KF, Atkinson MJ, Reich U, et al. E-cadherin gene mutations provide clues to diffuse type gastric carcinomas. Cancer Res. 1994; 54:3845-3852 (Pubitemid 24241205)
10. Berx G, Becker KF, Hofler H, et al. Mutations of the human E-cadherin (CDH1) gene. Hum Mutat.1998; 12: 226-237.
11. Yoshiura K, Kanai Y, Ochiai A, et al. Silencing of the E-cadherin invasion-suppressor gene by CpG methylation in human carcinomas. Proc Natl Acad Sci USA. 1995; 92: 7416-7419.
12. Baylin SB, Herman JG, Graff JR, et al. Alterations in DNA methylation: a fundamental aspect of neoplasia. Adv Cancer Res. 1998; 72: 141-196.
13. Kanai Y, Ushijima S, Hui AM, et al. The E-cadherin gene is silenced by CpG methylation in human hepatocellular carcinomas. Int J Cancer. 1997; 71: 355-359. (Pubitemid 27224296)
14. Graff JR, Herman JG, Lapidus RG, et al. E-cadherin expression is silenced by DNA hypermethylation in human breast and prostate carcinomas. Cancer Res. 1995; 55: 5195-5199.
15. Corn PG, Heath EI, Heitmiller R, et al. Frequent hypermethylation of the 5′ CpG island of E-cadherin in esophageal adenocarcinoma. Clin Cancer Res. 2001; 7: 2765-2769 (Pubitemid 32911382)
16. Yang CS. Vitamin nutrition and gastroesophageal cancer. J Nutr. 2000; 130:338S-339S.
17. Yokokawa Y, Ohta S, Hou J, et al. Ecological study on the risks of esophageal cancer in Ci-Xian, China: the importance of nutritional status and the use of well water. Int J Cancer .1999; 83:620-624. (Pubitemid 29508040)
18. Launoy G, Milan CH, Faivre J, et al. Alcohol,tobacco and oesophageal cancer: effects of the duration of consumption, mean intake and current and former consumption.Br J Cancer. 1997;75:1389-1396. (Pubitemid 27179835)
19. Jones PA, Buckley JD. The role of DNA methylation in cancer. Adv Cancer Res .1990; 54:1-23.
20. Siewert JR, Stein HJ. Classification of adenocarcinoma of the oesophagogastric junction. Br J Surg. 1998; 85, 1457-1459.
21. Herman JG, Graff JR, Myohanen S, et al. Methylation-specific PCR: a novel PCR assay for methylation status of CpG islands. Proc Natl Acad Sci USA .1996; 93:9821-9826. (Pubitemid 26296693)
22. Strathdee G, Brown R. Aberrant DNA methylation in cancer: potential clinical interventions. Expert Rev Mol Med. 2002; 4:1-17.
23. Sadot E, Simcha I, Shtutman M, et al. Inhibition of beta-catenin-mediated transactivation by cadherin derivatives. Proc Natl Acad Sci USA. 1998; 95: 15339-15344. (Pubitemid 29018700)
24. Chan AO, Lam SK, Wong BC, et al. Promoter methylation of E-cadherin gene in gastric mucosa associated with Helicobacter pylori infection and in gastric cancer. Gut. 2003, 52: 502-506. (Pubitemid 36363400)
25. Rountree MR, Bachman KE, Baylin SB. DNMT1 binds HDAC2 and a new co-repressor, DMAP1, to form a complex at replication foci. Nat Genet. 2000; 25: 269-277.
26. Graff JR, Greenberg VE, Herman JG, et al. Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma . Cancer Res. 1998, 58: 2063-2066.
27. Klump B, Hsieh CJ, Holzmann K, et al. Hypermethylation of the CDKN2/p16 promoter during neoplastic progression in Barrett's esophagus. Gastroenterology. 1998;115: 1381-1386. (Pubitemid 28545988)
28. Bird A. Molecular biology. Methylation talk between histones and DNA. Science. 2001, 294: 2113-2115