Real time monitoring of sickle cell hemoglobin fiber formation by UV resonance Raman spectroscopy

Biochemistry

Volumn 48, Issue 41, 2009, Pages 9903-9911

  Knee, Kelly M ^a,b   Mukerji, Ishita ^a  

^a WESLEYAN UNIVERSITY   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AROMATIC AMINO ACID; FIBER FORMATION; FUNCTION OF TIME; H-BOND STRENGTH; HYDROPHOBIC POCKETS; INITIAL STAGES; INTENSITY CHANGE; INTERMOLECULAR CONTACTS; LONG FIBER; MACROFIBERS; MOLECULAR INSIGHTS; MUTATION SITES; POLYMERIZATION PROCESS; PROGRESS CURVES; REAL TIME; REAL TIME MONITORING; SICKLE CELL; SIGNAL INTENSITIES; TETRAMERS; TIME POINTS; TURBIDITY MEASUREMENTS; UV-RESONANCE RAMAN SPECTROSCOPY; VIBRATIONAL MODES;

AMINES; AMINO ACIDS; CELL MEMBRANES; ELECTRON TRANSITIONS; HEMOGLOBIN; HYDROPHOBICITY; MONITORING; ORGANIC ACIDS; RAMAN SCATTERING; RAMAN SPECTROSCOPY; RESONANCE; TURBIDITY;

FIBERS;

AROMATIC AMINO ACID; HEMOGLOBIN S; LEUCINE; PHENYLALANINE; TETRAMER; TRYPSIN; TYROSINE;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HYDROGEN BOND; HYDROPHOBICITY; KINETICS; POLYMERIZATION; PRIORITY JOURNAL; RAMAN SPECTROMETRY; TURBIDITY; ULTRAVIOLET SPECTROSCOPY; VIBRATION;

AMINO ACID SUBSTITUTION; ANEMIA, SICKLE CELL; CRYSTALLOGRAPHY, X-RAY; HEMOGLOBIN, SICKLE; HEMOLYSIS; HUMANS; KINETICS; MODELS, MOLECULAR; MUTATION; PHENYLALANINE; PROTEIN CONFORMATION; PROTEIN SUBUNITS; SPECTRUM ANALYSIS, RAMAN; TRYPTOPHAN; TYROSINE;

EID: 70350062719     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi901352m     Document Type: Article

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