Polymerization of deoxy-sickle cell hemoglobin in high-phosphate buffer

Journal of Structural Biology

Volumn 131, Issue 3, 2000, Pages 197-209

  Wang, Zhiping ^a   Kishchenko, Grigoriy ^a   Chen, Yimei ^a   Josephs, Robert ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BUFFER; DEOXYHEMOGLOBIN; HEMOGLOBIN S; PHOSPHATE;

ARTICLE; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; FOURIER TRANSFORMATION; HUMAN; HUMAN TISSUE; PH; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; PROTEIN STRUCTURE; SICKLE CELL ANEMIA; SITE DIRECTED MUTAGENESIS;

EID: 0033763140     PISSN: 10478477     EISSN: None     Source Type: Journal    
DOI: 10.1006/jsbi.2000.4295     Document Type: Article

References (30)

1. Gelation of deoxyhemoglobin A in concentrated phosphate buffer. Exhibition of delay time prior to aggregation and crystallization of deoxyhemoglobin A
2. Polymerization of deoxyhemoglobin in C Harlem (beta 6 Glu replaced by Val, beta 73 Asp replaced by Asn). The effect of beta 73 asparagine on the gelation and crystallization of hemoglobin
3. Kinetics of the polymerization of hemoglobin in high and low phosphate buffers
4. Reconstruction of helical particles with variable pitch
5. Polymer structure and solubility of deoxyhemoglobin S in the presence of high concentrations of volume-excluding 70-kDa dextran
6. Structural analysis of sickle cell hemoglobin polymers. I. Sickle hemoglobin fibers
7. Structural analysis of sickle cell hemoglobin polymers. III. The structure of sickle hemoglobin fibers within fascicles
8. Double strand packing in hemoglobin S fibers
9. The reconstruction of a three-dimensional structure from projections and its application to electron microscopy
10. Reconstruction of three-dimensional images from electron micrographs of structures with helical symmetry
11. Three-dimensional reconstruction of the 14-filament fibers of hemoglobins
12. Sickle cell hemoglobin polymerization
13. The high resolution crystal structure of deoxyhemoglobin S
14. Participation and strength of interaction of lysine 95(beta) in the polymerization of hemoglobin S as determined by its site-directed substitution by isoleucine
15. A physical description of hemoglobin S gelation
16. Diffraction by helical structures
17. Variable pitch in frozen-hydrated sickle hemoglobin fibers: An image analysis model study
18. Refined crystal structure of deoxyhemoglobin S. I. Restrained least-squares refinement at 3.0-Å resolution
19. Refined crystal structure of deoxyhemoglobin S. II. Molecular interactions in the crystal
20. Macrofiber structure and the dynamics of sickle hemoglobin crystallization
21. Pairings and polarities of the 14 strands in sickle cell hemoglobin fibers
22. Studies on the fiber-to-crystal transition of sickle cell hemoglobin in polyethylene glycol
23. Intermolecular contacts within sickle hemoglobin fibers
24. Analysis of intermolecular contacts within sickle hemoglobin fibers: Effect of site-specific substitutions, fiber pitch, and double-strand disorder
25. Crystallization of sickle cell hemoglobin by fiber alignment and fusion
26. Polymorphic assemblies of double strands of sickle cell hemoglobin: Manifold pathways of deoxyhemoglobin S crystallization
27. Crystal structure of sickle-cell deoxyhemoglobin at 5 Å resolution
28. Crystal structure of sickle-cell deoxyhemoglobin