Monocomponent hexa- and dodecaethylene glycol succinyl-tocopherol esters: Self-assembly structures, cellular uptake and sensitivity to enzyme hydrolysis

Biochemical Pharmacology

Volumn 78, Issue 12, 2009, Pages 1464-1474

  Folmer, Britta M ^a   Barron, Denis ^a   Hughes, Eric ^a   Miguet, Laurence ^a   Sanchez, Belén ^a   Heudi, Olivier ^a   Rouvet, Martine ^a   Sagalowicz, Laurent ^a   Callier, Philippe ^a   Michel, Martin ^a   Williamson, Gary ^a,b  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

Caco 2 cell; Docking model; Esterase; Self assembly structure; Vitamin E

Indexed keywords

ALPHA TOCOPHEROL DERIVATIVE; ALPHA TOCOPHEROL SUCCINYLBENZYLDODECAETHYLENE GLYCOL; ALPHA TOCOPHEROL SUCCINYLBENZYLHEXAETHYLENE GLYCOL; ALPHA TOCOPHEROL SUCCINYLDODECAETHYLENE GLYCOL; ALPHA TOCOPHEROL SUCCINYLHEXAETHYLENE GLYCOL; CARBOXYLESTERASE; UNCLASSIFIED DRUG;

ARTICLE; CELL STRAIN CACO 2; COMPUTER MODEL; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG METABOLISM; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; HUMAN; HUMAN CELL; HYDROLYSIS; MICELLE; MOLECULAR DOCKING; PRIORITY JOURNAL;

ALPHA-TOCOPHEROL; BINDING SITES; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; CARBOXYLIC ESTER HYDROLASES; HUMANS; HYDROLYSIS; POLYETHYLENE GLYCOLS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 70350061815     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2009.07.009     Document Type: Article

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