Mechanism of cadmium-mediated inhibition of Msh2-Msh6 function in DNA mismatch repair

Biochemistry

Volumn 48, Issue 40, 2009, Pages 9492-9502

  Wieland, Markus ^a,b   Levin, Mikhail K ^c   Hingorani, Karan S ^d   Noah Biro, F ^a   Hingorani, Manju M ^a  

^a WESLEYAN UNIVERSITY   (United States)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c DUKE UNIVERSITY MEDICAL CENTER   (United States)

^d ST XAVIER S COLLEGE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; ASPARTATES; ATP-ASE ACTIVITY; BASE PAIRS; BINDING MODELS; BIOLOGICAL PROCESS; CADMIUM TOXICITY; CARCINOGENIC EFFECTS; CRITICAL DETERMINANT; DNA BINDING; DNA REPAIR; ENZYMATIC ACTIVITIES; GLOBAL FITTING; INHIBITORY EFFECT; MISMATCH REPAIR; MONITORING CHANGE; PEPTIDE BACKBONES; PROTEIN STRUCTURES; SPECIFIC SITES; SULFHYDRYL GROUPS;

AMINES; BINDING ENERGY; BIOLOGICAL SYSTEMS; CADMIUM; CELL DEATH; DNA; ENZYME INHIBITION; GENES; NUCLEIC ACIDS; PROTEINS;

BINDING SITES;

ADENOSINE TRIPHOSPHATASE; ASPARTIC ACID; CADMIUM; CYSTEINE; HISTIDINE; PROTEIN MSH2; PROTEIN MSH6; THIOL GROUP;

APOPTOSIS; ARTICLE; BASE MISPAIRING; BINDING SITE; DNA BINDING; DNA REPAIR; ENZYME ACTIVITY; METAL BINDING; MISMATCH REPAIR; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN FUNCTION;

ADENOSINE TRIPHOSPHATE; BASE PAIR MISMATCH; BINDING SITES; CADMIUM; CADMIUM CHLORIDE; DNA REPAIR; DNA-BINDING PROTEINS; HYDROLYSIS; MUTS HOMOLOG 2 PROTEIN; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 70350054609     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9001248     Document Type: Article

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