Hydrogenation impairs the hypolipidemic and antioxidant effects of palm oil in rats

International Journal of Physical Sciences

Volumn 4, Issue 7, 2009, Pages 407-411

  Ojieh, Godwin C ^a   Idokpesi, Georginah O ^b   Eidangbe, George O ^a   Omage, Kingsley ^b   Oluba, Olarewaju M ^c  

^a AMBROSE ALLI UNIVERSITY   (Nigeria)

^b IGBINEDION UNIVERSITY   (Nigeria)

^c UNIVERSITY OF BENIN   (Nigeria)

Author keywords

Cardiovascular disease; Lipid excretion; Lipid peroxidation; Trans fats; Triacylglycerol

Indexed keywords

EID: 70350043131     PISSN: 19921950     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (27)

1. Allison DB, Egan SK, Barraj LM, Caughman C, Infante M, Heimbach JT (1999). Estimated intakes of trans fatty and other fatty acids in US population. J. Am. Diet Assoc. 99: 166-174.
2. Bracco U (1994). Effects of triglycerides structure on fat absorption. Am. J. Clin. Nutr. 60: 1002S-1009S.
3. Edem DO (2002). Palm oil: biochemical, physiological, and toxicological aspects: a review. Plant Food Num. Nutr. 57: 319-341.
4. Habig WH, Pabst MJ, Jacoby WB (1974). Glutathione- s- transferase - The first step in mercapturic acid formation. J. Biol. Chem. 249: 7130-7139.
5. Kamei M, Ohgaki S, Kanbe T, Niiya I, Mizutani H, Matsui-Yuasa I, Otani S, Morita S (1995). Effects of highly hydrogenated soybean oil and cholesterol on plasma, liver, and cholesterol, and fecal steroids in rats. Lipids. 30: 533-539.
6. Kaplan RJ, Greenwood CE (1998). Poor digestibility of fully hydrogenated soybean oil in rats: a potential benefit of hydrogenated fats and oils. J. Nutr. 128: 875-880.
7. Lichtenstein AH (1998). Trans fatty acd and blood lipid levels, Lp(a), parameters of cholesterol metabolism, and hemostatic factors. Review. Nutr. Biochem. 9: 244-248.
8. Lichtenstein AH, Ausman LM, Carrasco W, Jenner JL, Ordovas JM, Schaefer EJ (1993). Hydrogenation impairs the hypolipidemic effect of corn oil in humans. Hydrogenation, trans fatty acids, and plasma lipids. Arterioscler Thromb. 13: 154-161.
9. Lowry OH, Rosenbrough NJ, Farr A, Randall RJ (1951). Protein measurement with Folin phenol reagent. J. Biol. Chem. 193: 265-275.
10. Mensink RP, Katan M (1990). Effect of dietary trans fatty acid on highdensity and low-density lipoprotein cholesterol levels in healthysubjects. N. Engl. J. Med. 323: 439-445.
11. Oluba OM, Adeyemi O, Ojieh GC, Isiosio IO (2008). Fatty acid composition of Citrullus lanatus (egusi melon) and its effect on serum lipids and some serum enzymes. Internet J. Cardiovascular Res. 5:2.
12. Paolicchi A, Emdin M, Ghliozeni E, Grancia E, Passino C, Popoff G, Pompella, A (2004). Images in cardiovascular medicine. Human atherosclerotic plaques containing GGT enzyme activity. Circulation.109: 1440-1440
13. Paolicchi A, Emdi, M, Passino C, Lorenzini E, Titta F, Marchi S, Malvaldi G, Pompella A (2006). A beta-lipoprotein and LDL- associated serum gamma-glutamyl transpeptidase in patients with coronary atherosclerosis. Atherosclerosis 186: 80-85.
14. Puah CW, Choo YM, Ma N, Chuah CH (2007). The effect of physical refining on palm vitamin E (tocopherol, tocotrienol and tocomonoenol). Am J Appl Sci. 4(6): 374-377.
15. Racker E (1955). Glutathione reductase (liver and yeast). In: methods in Enzymol. 2: 722-725.
16. Roeschlau P, Bernt E, Gruber NJ (1974). Serum cholesterol determination procedure. Clin. Biochem. 12: 403-403
17. Rotruck JT, Pope AL, Ganther HE, Swanson AB, Hafeman DG, Hoekstra WG (1973). Selenium: biochemical role as a component of glutathione peroxidase. Science 179:588-590.
18. Sakono M, Takagi H, Sonoki H, Yoshida H, Iwamoto M, Ikade I, Imaizumi K (1997). Absorption and lymphatic transport of interesterified or mixed fats rich in saturated fatty acids and their effect on tissue lipids in rats. Nutr. Res. 17: 1131-1141.
19. Sanchez-Moreno C, Dorfman SE, Lichtenstein AH, Martin A (2004). Dietary fat types affect vitamin C and E and biomarkers of oxidative status in peripheral and brain tissues of golden Syrian hamsters. J. Nutr. 134: 655-660.
20. Speir CL, Wattenberg LW (1975). Alterations in microsomal metabolism of benzo(a) pyrene in mice fed butylated hydroxylanisole. J. Natl. Cancer Inst. 55: 469-472.
21. Sundram K, Khor HT, Ong ASH, Pathmanathan R (1989). Effect of dietary palm oils on mammary carcinogenesis in female rats induced by 7,12-dimethylbenzy(a)anthracene. Cancer Res. 49: 1447-1451.
22. Szaz G (1976). A kinetic photometric method for serum gamma-glutamyltranspeptidase. Clin. Chem. 15: 124-136.
23. Tiez NW (1990). Clinical Guide to Laboratory Tests. 2nd edn. WB Saunders Company, Philadelphia, USA, pp. 554-554
24. Tosaki A, Blasig I, Pali T, Ebert B (1990). Heart protection and radical trapping by DMPO during reperfusion in isolated working rat hearts. Free Radical Biol. Med. 8: 363-372.
25. Traber MG, Podda M, Weber C, Thiele J, Rallis M, Packer L (1997). Diet-derived and topically applied tocotrienols accumulate in the skin and protect the tissue against ultraviolet light-induced oxidative stress. Asia Pacific J. Clin Nutr. 6: 63-67.
26. Varshney R, Kale RK (1990). Effects of Calmodulin antagonist on radiation induced lipid peroxidation in microsomes. Intl. J. Rad. Biol. 58: 733-743.
27. Wilson TA, Mclntyre M, Nicolosi, RJ (2001). Trans fatty acids and cardiovascular risk. J. Nutr. Health Aging. 5: 184-187.