-
1
-
-
0003700872
-
-
version 1.0. IARC Cancer Base No.5, Lyon: IARC Press
-
Ferlay J, Bray F, Pisani P, Parkin DM. GLOBOCAN 2000: Cancer incidence, mortality and prevalence worldwide, version 1.0. IARC Cancer Base No.5, Lyon: IARC Press; 2001.
-
(2001)
GLOBOCAN 2000: Cancer Incidence, Mortality and Prevalence Worldwide
-
-
Ferlay, J.1
Bray, F.2
Pisani, P.3
Parkin, D.M.4
-
2
-
-
34247164679
-
Bladder cancer
-
Clark PE. Bladder cancer. Curr Opin Oncol 2007; 19: 241-247.
-
(2007)
Curr Opin Oncol
, vol.19
, pp. 241-247
-
-
Clark, P.E.1
-
3
-
-
33644841931
-
Genetic alterations in urothelial bladder carcinoma: An updated review
-
DOI 10.1002/cncr.21743
-
Mhawech-Fauceglia P, Cheney RT, Schwaller J. Genetic alterations in urothelial bladder carcinoma: an updated review. Cancer 2006; 106: 1205-1216. (Pubitemid 43363896)
-
(2006)
Cancer
, vol.106
, Issue.6
, pp. 1205-1216
-
-
Mhawech-Fauceglia, P.1
Cheney, R.T.2
Schwaller, J.3
-
4
-
-
54549092123
-
Molecular targeting in the treatment of either advanced or metastatic bladder cancer or both according to the signaling pathways
-
Wallerand H, Reiter RR, Ravaud A. Molecular targeting in the treatment of either advanced or metastatic bladder cancer or both according to the signaling pathways Curr Opin Urol 2008; 18: 524-532.
-
(2008)
Curr Opin Urol
, vol.18
, pp. 524-532
-
-
Wallerand, H.1
Reiter, R.R.2
Ravaud, A.3
-
5
-
-
34548435148
-
Targeted therapies in bladder cancer-an update
-
DOI 10.1016/j.urolonc.2007.05.011, PII S1078143907001445, Proceedings: Annual Meeting of the Society of Urologic Oncology (May 2006). Part I: Genitourinary Cancer Biology and Translation
-
Black PC, Agarwal PK, Dinney CPN. Targeted therapies in bladder cancer - an update. Urol Oncol 2007; 25: 433-438. (Pubitemid 47362765)
-
(2007)
Urologic Oncology: Seminars and Original Investigations
, vol.25
, Issue.5
, pp. 433-438
-
-
Black, P.C.1
Agarwal, P.K.2
Dinney, C.P.N.3
-
6
-
-
57849156199
-
The impact of variant histology on the outcome of bladder cancer treated with curative intent
-
Black PC, Brown GA, Dinney CP. The impact of variant histology on the outcome of bladder cancer treated with curative intent. Urol Oncol 2009; 27: 3-7.
-
(2009)
Urol Oncol
, vol.27
, pp. 3-7
-
-
Black, P.C.1
Brown, G.A.2
Dinney, C.P.3
-
7
-
-
54549099158
-
Gene therapy in bladder cancer
-
Bochner BH. Gene therapy in bladder cancer. Curr Op Urol 2008; 18: 519-523.
-
(2008)
Curr Op Urol
, vol.18
, pp. 519-523
-
-
Bochner, B.H.1
-
8
-
-
33748470058
-
Recent advances in intravesical drug/gene delivery
-
DOI 10.1021/mp060001j
-
Tyagi P, Wu PC, Chancellor M, Yoshimura N, Huang L. Recent advances in intravesical drug/gene delivery. Mol Pharm 2006; 3: 369-379. (Pubitemid 44351919)
-
(2006)
Molecular Pharmaceutics
, vol.3
, Issue.4
, pp. 369-379
-
-
Tyagi, P.1
Wu, P.-C.2
Chancellor, M.3
Yoshimura, N.4
Huang, L.5
-
9
-
-
34548443495
-
Current strategies for first and second line intravesical therapy for nonmuscle invasive bladder cancer
-
DOI 10.1097/MOU.0b013e3281c55f2b, PII 0004230720070900000012
-
Hendricksen K, Witjes JA. Current strategies for first and second line intravesical therapy for nonmuscle invasive bladder cancer. Curr Opin Urol 2007; 17: 352-357. (Pubitemid 47351133)
-
(2007)
Current Opinion in Urology
, vol.17
, Issue.5
, pp. 352-357
-
-
Hendricksen, K.1
Witjes, J.A.2
-
10
-
-
0036724805
-
Changes produced in the urothelium by traditional and newer therapeutic procedures for bladder cancer
-
DOI 10.1136/jcp.55.9.641
-
Lopez-Bertran A, Luque RJ, Mazzucchelli R, Scarpelli M, Montironi R. Changes produced in the urothelium by traditional and newer therapeutic procedures for bladder cancer. J Clin Pathol 2002; 55: 641-647. (Pubitemid 34970083)
-
(2002)
Journal of Clinical Pathology
, vol.55
, Issue.9
, pp. 641-647
-
-
Lopez-Beltran, A.1
Luque, R.J.2
Mazzucchelli, R.3
Scarpelli, M.4
Montironi, R.5
-
11
-
-
44749093232
-
Intravesical treatments of bladder cancer: Review
-
Shen Z, Shen T, Wientjes MG, O'Donnel MA, Au JL-S. Intravesical treatments of bladder cancer: Review. Pharm Res 2008; 25: 1500-1510.
-
(2008)
Pharm Res
, vol.25
, pp. 1500-1510
-
-
Shen, Z.1
Shen, T.2
Wientjes, M.G.3
O'Donnel, M.A.4
Au, J.L.-S.5
-
12
-
-
25144517088
-
Novel therapies in bladder cancer
-
Alonzi R, Hoskin P. Novel therapies in bladder cancer. Clin Oncol 2005; 17: 524-538.
-
(2005)
Clin Oncol
, vol.17
, pp. 524-538
-
-
Alonzi, R.1
Hoskin, P.2
-
13
-
-
33747506490
-
Understanding urothelial carcinoma through cancer pathways
-
Schultz WA. Understanding urothelial carcinoma through cancer pathways. Int J Cancer 2006; 119: 1513-1518.
-
(2006)
Int J Cancer
, vol.119
, pp. 1513-1518
-
-
Schultz, W.A.1
-
14
-
-
25444467767
-
Urothelial tumorigenesis: A tale of divergent pathways
-
Wu XR. Urothelial tumorigenesis: a tale of divergent pathways. Nat Rev Cancer 2005; 5: 713-725.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 713-725
-
-
Wu, X.R.1
-
15
-
-
37249003928
-
Oncogene addiction: Setting the stage for molecularly targeted cancer therapy
-
DOI 10.1101/gad.1609907
-
Sharma SV, Settleman J. Oncogene addiction: setting the stage for molecularly targeted cancer therapy. Genes Dev 2007; 21: 3214-3231. (Pubitemid 350277749)
-
(2007)
Genes and Development
, vol.21
, Issue.24
, pp. 3214-3231
-
-
Sharma, S.V.1
Settleman, J.2
-
16
-
-
38649109498
-
Molecular-targeted therapies: Lessons from years of clinical development
-
DOI 10.1016/j.ctrv.2007.07.019, PII S0305737207000977
-
Rosa DD, Ismael G, Lago LD, Awada A. Molecularly-targeted therapies: Lessons from years of clinical development. Cancer Treat Rev 2008; 34: 61-80. (Pubitemid 351168606)
-
(2008)
Cancer Treatment Reviews
, vol.34
, Issue.1
, pp. 61-80
-
-
Rosa, D.D.1
Ismael, G.2
Lago, L.D.3
Awada, A.4
-
17
-
-
28644451845
-
Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of gefitinib in bladder cancer cells
-
DOI 10.1158/0008-5472.CAN-05-1536
-
Kassouf W, Dinney CP, Brown G et al. Uncoupling between epidermal growth factor receptor and downstream signals defines resistance to the antiproliferative effect of Gefitinib in bladder cancer cells. Cancer Res 2005; 65: 10524-10535. (Pubitemid 41748146)
-
(2005)
Cancer Research
, vol.65
, Issue.22
, pp. 10524-10535
-
-
Kassouf, W.1
Dinney, C.P.N.2
Brown, G.3
McConkey, D.J.4
Diehl, A.J.5
Bar-Eli, M.6
Adam, L.7
-
18
-
-
27544503230
-
Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: Results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer)
-
DOI 10.1016/S0140-6736(05)67625-8, PII S0140673605676258
-
Thatcher N, Chang A, Parikh P et al. Gefitinib plus best supportive care in previously treated patients with refractory advanced non-small-cell lung cancer: results from a randomised, placebo-controlled, multicentre study (Iressa Survival Evaluation in Lung Cancer). Lancet 2005; 366: 1527-1537. (Pubitemid 41540110)
-
(2005)
Lancet
, vol.366
, Issue.9496
, pp. 1527-1537
-
-
Thatcher, N.1
Chang, A.2
Parikh, P.3
Pereira, J.R.4
Ciuleanu, T.5
Von Pawel, J.6
Thongprasert, S.7
Tan, E.H.8
Pemberton, K.9
Archer, V.10
Carroll, K.11
-
20
-
-
33745244755
-
Schedule Dependent Efficacy of Gefitinib and Docetaxel for Bladder Cancer
-
DOI 10.1016/j.juro.2006.03.072, PII S0022534706008196
-
Kassouf W, Luongo T, Brown G, Adam L, Dinney CP. Schedule dependent efficacy of gefitinib and docetaxel for bladder cancer. J Urol 2006; 176: 787-792. (Pubitemid 43927919)
-
(2006)
Journal of Urology
, vol.176
, Issue.2
, pp. 787-792
-
-
Kassouf, W.1
Luongo, T.2
Brown, G.3
Adam, L.4
Dinney, C.P.N.5
-
21
-
-
0037058715
-
HER2 overexpression in muscle-invasive urothelial carcinoma of the bladder: Prognostic implications
-
DOI 10.1002/ijc.10731
-
Krüger S, Weitsch G, Büttner H et al. HER2 overexpression in muscle-invasive urothelial carcinoma of the bladder: prognostic implications. Int J Cancer 2002; 102: 514-518. (Pubitemid 35316007)
-
(2002)
International Journal of Cancer
, vol.102
, Issue.5
, pp. 514-518
-
-
Kruger, S.1
Weitsch, G.2
Buttner, H.3
Matthiensen, A.4
Bohmer, T.5
Marquardt, T.6
Sayk, F.7
Feller, A.C.8
Bohle, A.9
-
22
-
-
34250218955
-
Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: Results of a multicenter phase II National Cancer Institute trial
-
DOI 10.1200/JCO.2006.08.0994
-
Hussain MH, McVicar GR, Petrylak DP et al; National Cancer Institute. Trastuzumab, paclitaxel, carboplatin, and gemcitabine in advanced human epidermal growth factor receptor-2/neu-positive urothelial carcinoma: results of a multicenter phase II National Cancer Institute trial. J Clin Oncol 2007; 25: 2218-2224. (Pubitemid 46954646)
-
(2007)
Journal of Clinical Oncology
, vol.25
, Issue.16
, pp. 2218-2224
-
-
Hussain, M.H.A.1
MacVicar, G.R.2
Petrylak, D.P.3
Dunn, R.L.4
Vaishampayan, U.5
Lara Jr., P.N.6
Chatta, G.S.7
Nanus, D.M.8
Glode, L.M.9
Trump, D.L.10
Chen, H.11
Smith, D.C.12
-
23
-
-
13444257366
-
Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451
-
Roberts WG, Whalen PM, Soderstrom E et al. Antiangiogenic and antitumor activity of a selective PDGFR tyrosine kinase inhibitor, CP-673,451. Cancer Res 2005; 65: 957-966. (Pubitemid 40216457)
-
(2005)
Cancer Research
, vol.65
, Issue.3
, pp. 957-966
-
-
Roberts, W.G.1
Whalen, P.M.2
Soderstrom, E.3
Moraski, G.4
Lyssikatos, J.P.5
Wang, H.-F.6
Cooper, B.7
Baker, D.A.8
Savage, D.9
Dalvie, D.10
Atherton, J.A.11
Ralston, S.12
Szewc, R.13
Kath, J.C.14
Lin, J.15
Soderstrom, C.16
Tkalcevic, G.17
Cohen, B.D.18
Pollack, V.19
Barth, W.20
Hungerford, W.21
Ung, E.22
more..
-
24
-
-
33846260566
-
Sorafenib for the treatment of advanced renal cell carcinoma
-
DOI 10.1158/1078-0432.CCR-06-1249
-
Kane RC, Farrell AT, Saber H et al. Sorafenib for the treatment of advanced renal cell carcinoma. Clin Cancer Res 2006; 12: 7271-7278. (Pubitemid 46095398)
-
(2006)
Clinical Cancer Research
, vol.12
, Issue.24
, pp. 7271-7278
-
-
Kane, R.C.1
Farrell, A.T.2
Saber, H.3
Tang, S.4
Williams, G.5
Jee, J.M.6
Liang, C.7
Booth, B.8
Chidambaram, N.9
Morse, D.10
Sridhara, R.11
Garvey, P.12
Justice, R.13
Pazdur, R.14
-
25
-
-
69349105667
-
Adjuvant and neoadjuvant small-molecule targeted therapy in high-risk renal cell carcinoma
-
Kapoor A, Gharajeh A, Sheikh A, Pinthus J. Adjuvant and neoadjuvant small-molecule targeted therapy in high-risk renal cell carcinoma. Curr Oncol 2009; 16(Suppl 1): S60-66.
-
(2009)
Curr Oncol
, vol.16
, Issue.SUPPL. 1
-
-
Kapoor, A.1
Gharajeh, A.2
Sheikh, A.3
Pinthus, J.4
-
26
-
-
38949162167
-
Randomized, double-blind, placebo-controlled phase II trial of maintenance sunitinib versus placebo after chemotherapy for patients with advanced urothelial carcinoma: Scientific rationale and study design
-
DOI 10.3816/CGC.2007.n.037
-
Bradley DA, Dunn R, Nanus D et al. Randomized, double-blind, placebo-controlled phase II trial of maintenance sunitinib versus placebo after chemotherapy for patients with advanced urothelial carcinoma: scientific rationale and study design. Clin Genitourin Cancer 2007; 5: 460-463. (Pubitemid 351219702)
-
(2007)
Clinical Genitourinary Cancer
, vol.5
, Issue.7
, pp. 460-463
-
-
Bradley, D.A.1
Dunn, R.2
Nanus, D.3
Stadler, W.4
Dreicer, R.5
Rosenberg, J.6
Smith, D.C.7
Hussain, M.8
-
28
-
-
0042830875
-
Ras oncogene mutations in urine sediments of patients with bladder cancer
-
Buyru N, Tigli H, Ozcan F, Dalay N. Ras oncogene mutations in urine sediments of patients with bladder cancer. J Biochem Mol Biol 2003; 36: 399-402. (Pubitemid 37100932)
-
(2003)
Journal of Biochemistry and Molecular Biology
, vol.36
, Issue.4
, pp. 399-402
-
-
Buyru, N.1
Tigli, H.2
Ozcan, F.3
Dalay, N.4
-
29
-
-
21144440538
-
A multinomial Phase II study of lonafarnib (SCH 66336) in patients with refractory urothelial cancer
-
DOI 10.1016/j.urolonc.2004.12.012, PII S1078143904002728
-
Winquist E, Moore MJ, Chi KN et al. A multinomial phase II study of lonafarnib (SCH 66336) in patients with refractory urothelial cancer. Urol Oncol 2005; 23: 143-149. (Pubitemid 40720377)
-
(2005)
Urologic Oncology: Seminars and Original Investigations
, vol.23
, Issue.3
, pp. 143-149
-
-
Winquist, E.1
Moore, M.J.2
Chi, K.N.3
Ernst, D.S.4
Hirte, H.5
North, S.6
Powers, J.7
Walsh, W.8
Boucher, T.9
Patton, R.10
Seymour, L.11
-
30
-
-
18044383103
-
A phase II trial of R115777, an oral farnesyl transferase inhibitor, in patients with advanced urothelial tract transitional cell carcinoma
-
Rosenberg JE, von der Maase H, Seigne JD et al. A phase II trial of R115777, an oral farnesyl transferase inhibitor, in patients with advanced urothelial tract transitional cell carcinoma. Cancer 2005; 103: 2035-2041.
-
(2005)
Cancer
, vol.103
, pp. 2035-2041
-
-
Rosenberg, J.E.1
Von Der Maase, H.2
Seigne, J.D.3
-
31
-
-
51349111250
-
Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model
-
Kinkade CW, Castillo-Martin M, Puzio-Kuter A et al. Targeting AKT/mTOR and ERK MAPK signaling inhibits hormone-refractory prostate cancer in a preclinical mouse model. J Clin Invest 2008; 118: 3051-3064.
-
(2008)
J Clin Invest
, vol.118
, pp. 3051-3064
-
-
Kinkade, C.W.1
Castillo-Martin, M.2
Puzio-Kuter, A.3
-
32
-
-
57349194139
-
Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers
-
Engelman JA, Chen L, Tan X et al. Effective use of PI3K and MEK inhibitors to treat mutant Kras G12D and PIK3CA H1047R murine lung cancers. Nat Med 2008; 14: 1351-1356.
-
(2008)
Nat Med
, vol.14
, pp. 1351-1356
-
-
Engelman, J.A.1
Chen, L.2
Tan, X.3
-
33
-
-
58749097239
-
LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition
-
Mahoney CL, Choudhury B, Davies H et al. LKB1/KRAS mutant lung cancers constitute a genetic subset of NSCLC with increased sensitivity to MAPK and mTOR signalling inhibition. Br J Cancer 2009; 100: 370-375.
-
(2009)
Br J Cancer
, vol.100
, pp. 370-375
-
-
Mahoney, C.L.1
Choudhury, B.2
Davies, H.3
-
34
-
-
60549102667
-
Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder cancer
-
Fechner G, Classen K, Schmidt D, Hauser S, Móller SC. Rapamycin inhibits in vitro growth and release of angiogenetic factors in human bladder cancer. Urology 2009; 73: 665-668.
-
(2009)
Urology
, vol.73
, pp. 665-668
-
-
Fechner, G.1
Classen, K.2
Schmidt, D.3
Hauser, S.4
Móller, S.C.5
-
35
-
-
36849056135
-
Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex
-
Stravopodis DJ, Margaritis LH, Voutsinas GE. Drug-mediated targeted disruption of multiple protein activities through functional inhibition of the Hsp90 chaperone complex. Curr Med Chem 2007; 14: 3122-3138.
-
(2007)
Curr Med Chem
, vol.14
, pp. 3122-3138
-
-
Stravopodis, D.J.1
Margaritis, L.H.2
Voutsinas, G.E.3
-
36
-
-
67651006061
-
Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions
-
Sos ML, Michel K, Zander T et al. Predicting drug susceptibility of non-small cell lung cancers based on genetic lesions. J Clin Invest 2009; 119: 1727-1740.
-
(2009)
J Clin Invest
, vol.119
, pp. 1727-1740
-
-
Sos, M.L.1
Michel, K.2
Zander, T.3
-
37
-
-
64749088834
-
Emerging treatments for multiple myeloma: Beyond immunomodulatory drugs and bortezomib
-
Mitsiades CS, Hideshima T, Chauhan D et al. Emerging treatments for multiple myeloma: beyond immunomodulatory drugs and bortezomib. Semin Hematol 2009; 46: 166-175.
-
(2009)
Semin Hematol
, vol.46
, pp. 166-175
-
-
Mitsiades, C.S.1
Hideshima, T.2
Chauhan, D.3
-
38
-
-
33845624653
-
Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer
-
DOI 10.1038/sj.bjc.6603482, PII 6603482
-
Christoph F, Kempkensteffen C, Weikert S et al. Methylation of tumour suppressor genes APAF-1 and DAPK-1 and in vitro effects of demethylating agents in bladder and kidney cancer. Br J Cancer 2006; 95: 1701-1707. (Pubitemid 44950797)
-
(2006)
British Journal of Cancer
, vol.95
, Issue.12
, pp. 1701-1707
-
-
Christoph, F.1
Kempkensteffen, C.2
Weikert, S.3
Kollermann, J.4
Krause, H.5
Miller, K.6
Schostak, M.7
Schrader, M.8
-
39
-
-
34547122494
-
HDAC inhibitors: Clinical update and mechanism-based potential
-
Glaser KB. HDAC inhibitors: clinical update and mechanism-based potential. Biochem Pharmacol 2007; 74: 659-671.
-
(2007)
Biochem Pharmacol
, vol.74
, pp. 659-671
-
-
Glaser, K.B.1
-
40
-
-
0037276902
-
The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells
-
Zhu WG, Otterson GA. The interaction of histone deacetylase inhibitors and DNA methyltransferase inhibitors in the treatment of human cancer cells. Curr Med Chem Anticancer Agents 2003; 3: 187-199.
-
(2003)
Curr Med Chem Anticancer Agents
, vol.3
, pp. 187-199
-
-
Zhu, W.G.1
Otterson, G.A.2
-
41
-
-
0038679686
-
Cyclin e overexpression and amplification in human tumours
-
DOI 10.1002/path.1356
-
Schraml P, Bucher C, Bissig H et al. Cyclin E overexpression and amplification in human tumours. J Pathol 2003; 200: 375-382. (Pubitemid 36827312)
-
(2003)
Journal of Pathology
, vol.200
, Issue.3
, pp. 375-382
-
-
Schraml, P.1
Bucher, C.2
Bissig, H.3
Nocito, A.4
Haas, P.5
Wilber, K.6
Seelig, S.7
Kononen, J.8
Mihatsch, M.J.9
Dirnhofer, S.10
Sauter, G.11
-
42
-
-
26044483061
-
Inhibitors of cyclin-dependent kinase modulators for cancer therapy
-
Senderowicz AM. Inhibitors of cyclin-dependent kinase modulators for cancer therapy. Prog Drug Res 2005; 63: 183-206.
-
(2005)
Prog Drug Res
, vol.63
, pp. 183-206
-
-
Senderowicz, A.M.1
-
43
-
-
58049209691
-
You never know: Cdk inhibitors as anti-cancer drugs
-
Hunt T. You never know: Cdk inhibitors as anti-cancer drugs. Cell Cycle 2008; 7: 3789-3790.
-
(2008)
Cell Cycle
, vol.7
, pp. 3789-3790
-
-
Hunt, T.1
-
44
-
-
54749111456
-
Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice
-
Rao CV, Swamy MV, Patlolla JM, Kopelovich L. Suppression of familial adenomatous polyposis by CP-31398, a TP53 modulator, in APCmin/+ mice. Cancer Res 2008; 68: 7670-7675.
-
(2008)
Cancer Res
, vol.68
, pp. 7670-7675
-
-
Rao, C.V.1
Swamy, M.V.2
Patlolla, J.M.3
Kopelovich, L.4
-
45
-
-
65449144050
-
PRIMA-1 reactivates mutant p53 by covalent binding to the core domain
-
Lambert JM, Gorzov P, Veprintsev DB et al. PRIMA-1 reactivates mutant p53 by covalent binding to the core domain. Cancer Cell 2009; 15: 376-388.
-
(2009)
Cancer Cell
, vol.15
, pp. 376-388
-
-
Lambert, J.M.1
Gorzov, P.2
Veprintsev, D.B.3
-
46
-
-
0033179760
-
BCL-2 family members and the mitochondria in apoptosis
-
Gross A, McDonnell JM, Korsmeyer SJ. BCL-2 family members and the mitochondria in apoptosis. Genes Dev 1999; 13: 1899-1911. (Pubitemid 29407357)
-
(1999)
Genes and Development
, vol.13
, Issue.15
, pp. 1899-1911
-
-
Gross, A.1
McDonnell, J.M.2
Korsmeyer, S.J.3
-
47
-
-
0028958030
-
Bcl-2: Prevention of apoptosis as a mechanism of drug resistance
-
Reed JC. Bcl-2: prevention of apoptosis as a mechanism of drug resistance. Hematol Oncol Clin North Am 1995; 9: 451-473.
-
(1995)
Hematol Oncol Clin North Am
, vol.9
, pp. 451-473
-
-
Reed, J.C.1
-
48
-
-
68449085118
-
Phase III randomised study of dexamethasone with or without oblimersen sodium for patients with advanced multiple myeloma
-
Chanan-Khan AA, Niesvizky R, Hohl RJ et al. Phase III randomised study of dexamethasone with or without oblimersen sodium for patients with advanced multiple myeloma. Leuk Lymphoma 2009; 50: 559-565.
-
(2009)
Leuk Lymphoma
, vol.50
, pp. 559-565
-
-
Chanan-Khan, A.A.1
Niesvizky, R.2
Hohl, R.J.3
-
49
-
-
0037852202
-
The proteasome: Structure, function, and role in the cell
-
Adams J. The proteasome: structure, function, and role in the cell. Cancer Treat Rev 2003; 29 (Suppl 1): 3-9. (Pubitemid 36626287)
-
(2003)
Cancer Treatment Reviews
, vol.29
, Issue.SUPPL. 1
, pp. 3-9
-
-
Adams, J.1
-
50
-
-
33846208703
-
Combination therapy with IFN-alpha plus bortezomib induces apoptosis and inhibits angiogenesis in human bladder cancer cells
-
Papageorgiou A, Kamat A, Benedict WF, Dinney C, McConkey DJ. Combination therapy with IFN-alpha plus bortezomib induces apoptosis and inhibits angiogenesis in human bladder cancer cells. Mol Cancer Ther 2006; 5: 3032-3041.
-
(2006)
Mol Cancer Ther
, vol.5
, pp. 3032-3041
-
-
Papageorgiou, A.1
Kamat, A.2
Benedict, W.F.3
Dinney, C.4
McConkey, D.J.5
-
51
-
-
0034090097
-
Angiogenesis: Potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation
-
Griffioen AW, Molema G. Angiogenesis: potentials for pharmacologic intervention in the treatment of cancer, cardiovascular diseases, and chronic inflammation. Pharmacol Rev 2000; 52: 237-268. (Pubitemid 30368433)
-
(2000)
Pharmacological Reviews
, vol.52
, Issue.2
, pp. 237-268
-
-
Griffioen, A.W.1
Molema, G.2
-
52
-
-
0036782278
-
VEGF and the quest for tumour angiogenesis factors
-
DOI 10.1038/nrc909
-
Ferrara N. VEGF and the quest for tumour angiogenesis factors. Nat Rev Cancer 2002; 2: 795-803. (Pubitemid 37328914)
-
(2002)
Nature Reviews Cancer
, vol.2
, Issue.10
, pp. 795-803
-
-
Ferrara, N.1
-
53
-
-
0032932495
-
Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis
-
Aotake T, Lu CD, Chiba Y, Muraoka R, Tanigawa N. Changes of angiogenesis and tumor cell apoptosis during colorectal carcinogenesis. Clin Cancer Res 1999; 5: 135-142. (Pubitemid 29045186)
-
(1999)
Clinical Cancer Research
, vol.5
, Issue.1
, pp. 135-142
-
-
Aotake, T.1
Lu, C.-D.2
Chiba, Y.3
Muraoka, R.4
Tanigawa, N.5
-
54
-
-
65349189892
-
Targeting angiogenesis in bladder cancer
-
Elfiky AA, Rosenberg JE. Targeting angiogenesis in bladder cancer. Curr Oncol Rep 2009; 11: 244-249.
-
(2009)
Curr Oncol Rep
, vol.11
, pp. 244-249
-
-
Elfiky, A.A.1
Rosenberg, J.E.2
-
55
-
-
67649313813
-
Management of bladder cancer: Current and emerging strategies
-
Agarwal N, Hussain M. Management of bladder cancer: current and emerging strategies. Drugs 2009; 69: 1173-1187.
-
(2009)
Drugs
, vol.69
, pp. 1173-1187
-
-
Agarwal, N.1
Hussain, M.2
-
56
-
-
9244228576
-
Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors
-
DOI 10.1159/000081101
-
Määttä M, Santala M, Soini Y, Talvensaari-Mattila A, Turpeenniemi-Hujanen T Matrix metalloproteinases 2 and 9 and their tissue inhibitors in low malignant potential ovarian tumors. Tumour Biol 2004; 25: 188-192. (Pubitemid 39551745)
-
(2004)
Tumor Biology
, vol.25
, Issue.4
, pp. 188-192
-
-
Maatta, M.1
Santala, M.2
Soini, Y.3
Talvensaari-Mattilaa, A.4
Turpeenniemi-Hujanenc, T.5
-
57
-
-
9344271530
-
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis
-
Pellikainen JM, Ropponen KM, Kataja VV, Kellokoski JK, Eskelinen MJ, Kosma VM. Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis. Clin Cancer Res 2004; 10: 7621-7628.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 7621-7628
-
-
Pellikainen, J.M.1
Ropponen, K.M.2
Kataja, V.V.3
Kellokoski, J.K.4
Eskelinen, M.J.5
Kosma, V.M.6
-
58
-
-
33846171956
-
Proteomic validation of protease drug targets: Pharmacoproteomics of matrix metalloproteinase inhibitor drugs using isotope-coded affinity tag labelling and tandem mass spectrometry
-
Butler GS, Overall CM. Proteomic validation of protease drug targets: pharmacoproteomics of matrix metalloproteinase inhibitor drugs using isotope-coded affinity tag labelling and tandem mass spectrometry. Curr Pharm Des 2007; 13: 263-270.
-
(2007)
Curr Pharm des
, vol.13
, pp. 263-270
-
-
Butler, G.S.1
Overall, C.M.2
-
59
-
-
33646594999
-
Phase II, parallel-design study of preoperative combined modality therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma
-
DOI 10.1007/s10637-006-5934-5
-
Heath EI, Burtness BA, Kleinberg L et al. Phase II, parallel-design study of preoperative combined modality therapy and the matrix metalloprotease (mmp) inhibitor prinomastat in patients with esophageal adenocarcinoma. Invest New Drugs 2006; 24: 135-140. (Pubitemid 43723905)
-
(2006)
Investigational New Drugs
, vol.24
, Issue.2
, pp. 135-140
-
-
Heath, E.I.1
Burtness, B.A.2
Kleinberg, L.3
Salem, R.R.4
Yang, S.C.5
Heitmiller, R.F.6
Canto, M.I.7
Knisely, J.P.S.8
Topazian, M.9
Montgomery, E.10
Tsottles, N.11
Pithavala, Y.12
Rohmiller, B.13
Collier, M.14
Forastiere, A.A.15
-
60
-
-
70350074717
-
Perspectives in vector development for systemic cancer gene therapy
-
Hatefi A, Canine BF. Perspectives in vector development for systemic cancer gene therapy. Gene Ther Mol Biol 2009; 13: 15-19.
-
(2009)
Gene Ther Mol Biol
, vol.13
, pp. 15-19
-
-
Hatefi, A.1
Canine, B.F.2
-
61
-
-
65749089629
-
Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis
-
Dorer DE, Nettelbeck DM. Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis. Adv Drug Deliv Rev 2009; 61: 554-571.
-
(2009)
Adv Drug Deliv Rev
, vol.61
, pp. 554-571
-
-
Dorer, D.E.1
Nettelbeck, D.M.2
-
62
-
-
30944446391
-
Efficacy of a single intravesical treatment with Ad-IFN/Syn 3 is dependent on dose and urine IFN concentration obtained: Implications for clinical investigation
-
DOI 10.1038/sj.cgt.7700865, PII 7700865
-
Tao Z, Connor RJ, Ashoori F et al. Efficacy of a single intravesical treatment with Ad-IFN/Syn 3 is dependent on dose and urine IFN concentration obtained: implications for clinical investigation. Cancer Gene Ther 2006; 13: 125-130. (Pubitemid 43113413)
-
(2006)
Cancer Gene Therapy
, vol.13
, Issue.2
, pp. 125-130
-
-
Tao, Z.1
Connor, R.J.2
Ashoori, F.3
Dinney, C.P.N.4
Munsell, M.5
Philopena, J.A.6
Benedict, W.F.7
-
63
-
-
29344432052
-
AdCD40L gene therapy counteracts T regulatory cells and cures aggressive tumors in an orthotopic bladder cancer model
-
Loskog AS, Fransson ME, Totterman TT. AdCD40L gene therapy counteracts T regulatory cells and cures aggressive tumors in an orthotopic bladder cancer model. Clin Cancer Res 2005; 11: 8816-8821.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 8816-8821
-
-
Loskog, A.S.1
Fransson, M.E.2
Totterman, T.T.3
-
64
-
-
1842532969
-
Inhibition of Orthotopic Human Bladder Tumor Growth by Lentiviral Gene Transfer of Endostatin
-
DOI 10.1158/1078-0432.CCR-03-0099
-
Kikuchi E, Menendez S, Ohori M, Cordon-Cardo C, Kasahara N, Bochner BH. Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin. Clin Cancer Res 2004; 10: 1835-1842. (Pubitemid 38435575)
-
(2004)
Clinical Cancer Research
, vol.10
, Issue.5
, pp. 1835-1842
-
-
Kikuchi, E.1
Menendez, S.2
Ohori, M.3
Cordon-Cardo, C.4
Kasahara, N.5
Bochner, B.H.6
-
65
-
-
0033747531
-
Gene therapy of human bladder cancer with adenovirus-mediated antisense basic fibroblast growth factor
-
Inoue K, Perrotte P, Wood CG, Slaton JW, Sweeney P, Dinney CP. Gene therapy of human bladder cancer with adenovirus-mediated antisense basic fibroblast growth factor. Clin Cancer Res 2000; 6: 4422-4431. (Pubitemid 30840198)
-
(2000)
Clinical Cancer Research
, vol.6
, Issue.11
, pp. 4422-4431
-
-
Inoue, K.1
Perrotte, P.2
Wood, C.G.3
Slaton, J.W.4
Sweeney, P.5
Dinney, C.P.N.6
-
66
-
-
33750553612
-
Low-dose etoposide enhances telomerase-dependent adenovirus-mediated cytosine deaminase gene therapy through augmentation of adenoviral infection and transgene expression in a syngeneic bladder tumor model
-
Shieh GS, Shiau AL, Yo YT et al. Low-dose etoposide enhances telomerase-dependent adenovirus-mediated cytosine deaminase gene therapy through augmentation of adenoviral infection and transgene expression in a syngeneic bladder tumor model. Cancer Res 2006; 66: 9957-9966.
-
(2006)
Cancer Res
, vol.66
, pp. 9957-9966
-
-
Shieh, G.S.1
Shiau, A.L.2
Yo, Y.T.3
-
67
-
-
0035036652
-
Gene therapy for bladder cancer using adenoviral vector
-
Wada Y, Gotoh A, Shirakawa T, Hamada K, Kamidono S. Gene therapy for bladder cancer using adenoviral vector. Mol Urol 2001; 5: 47-52. (Pubitemid 32448695)
-
(2001)
Molecular Urology
, vol.5
, Issue.2
, pp. 47-52
-
-
Wada, Y.1
Gotoh, A.2
Shirakawa, T.3
Hamada, K.4
Kamidono, S.5
-
68
-
-
32844458628
-
Growth inhibition efficacy of an adenovirus expressing dual therapeutic genes, wild-type p53, and anti-erbB2 ribozyme, against human bladder cancer cells
-
DOI 10.1038/sj.cgt.7700892, PII 7700892
-
Irie A, Matsumoto K, Anderegg B et al. Growth inhibition efficacy of an adenovirus expressing dual therapeutic genes, wild-type p53, and anti-erbB2 ribozyme, against human bladder cancer cells. Cancer Gene Ther 2006; 13: 298-305. (Pubitemid 43255767)
-
(2006)
Cancer Gene Therapy
, vol.13
, Issue.3
, pp. 298-305
-
-
Irie, A.1
Matsumoto, K.2
Anderegg, B.3
Kuruma, H.4
Kashani-Sabet, M.5
Scanlon, K.J.6
Uchida, T.7
Baba, S.8
-
69
-
-
33751549008
-
Additional gene therapy with rAAV-wt-p53 enhanced the efficacy of cisplatin in human bladder cancer cells
-
DOI 10.1159/000096341
-
Ruifa H, Liwei L, Binxin L, Ximing L. Additional gene therapy with rAAV-wt-p53 enhanced the efficacy of cisplatin in human bladder cancer cells. Urol Int 2006; 77: 355-361. (Pubitemid 44837006)
-
(2006)
Urologia Internationalis
, vol.77
, Issue.4
, pp. 355-361
-
-
Ruifa, H.1
Liwei, L.2
Binxin, L.3
Ximing, L.4
-
70
-
-
29044436777
-
P53 protein transduction therapy: Successful targeting and inhibition of the growth of the bladder cancer cells
-
DOI 10.1016/j.eururo.2005.08.019, PII S0302283805005233
-
Inoue M, Tomizawa K, Matsushita M et al. p53 protein transduction therapy: successful targeting and inhibition of the growth of the bladder cancer cells. Eur Urol 2006; 49: 161-168. (Pubitemid 41789974)
-
(2006)
European Urology
, vol.49
, Issue.1
, pp. 161-168
-
-
Inoue, M.1
Tomizawa, K.2
Matsushita, M.3
Lu, Y.-F.4
Yokoyama, T.5
Yanai, H.6
Takashima, A.7
Kumon, H.8
Matsui, H.9
-
71
-
-
0025304297
-
Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells
-
Horowitz JM, Park SH, Bogenmann E et al. Frequent inactivation of the retinoblastoma anti-oncogene is restricted to a subset of human tumor cells. Proc Natl Acad Sci U S A 1990; 87: 2775-2779. (Pubitemid 20141822)
-
(1990)
Proceedings of the National Academy of Sciences of the United States of America
, vol.87
, Issue.7
, pp. 2775-2779
-
-
Horowitz, J.M.1
Park, S.-H.2
Bogenmann, E.3
Cheng, J.-C.4
Yandell, D.W.5
Kaye, F.J.6
Minna, J.D.7
Dryja, T.P.8
Weinberg, R.A.9
-
72
-
-
0028276710
-
Mutation spectrum of the retinoblastoma gene in osteosarcomas
-
Wadayama B, Toguchida J, Shimizu T et al. Mutation spectrum of the retinoblastoma gene in osteosarcomas. Cancer Res 1994; 54: 3042-3048. (Pubitemid 24187793)
-
(1994)
Cancer Research
, vol.54
, Issue.11
, pp. 3042-3048
-
-
Wadayama, B.-I.1
Toguchida, J.2
Shimizu, T.3
Ishizaki, K.4
Sasaki, M.S.5
Kotoura, Y.6
Yamamuro, T.7
-
73
-
-
0037442425
-
Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells
-
Zhang X, Multani AS, Zhou JH et al. Adenoviral-mediated retinoblastoma 94 produces rapid telomere erosion, chromosomal crisis, and caspase-dependent apoptosis in bladder cancer and immortalized human urothelial cells but not in normal urothelial cells. Cancer Res 2003; 63: 760-765. (Pubitemid 36231972)
-
(2003)
Cancer Research
, vol.63
, Issue.4
, pp. 760-765
-
-
Zhang, X.1
Multani, A.S.2
Zhou, J.-H.3
Shay, J.W.4
McConkey, D.5
Dong, L.6
Kim, C.-S.7
Rosser, C.J.8
Pathak, S.9
Benedict, W.F.10
|