Temporal dynamic changes of phenotypic expression of peripheral CD4 cells during environmental allergen challenge in an experimental model of canine atopic dermatitis: A pilot study

Journal of Veterinary Medical Science

Volumn 71, Issue 9, 2009, Pages 1177-1181

  Simpson, Andrew ^a   Maeda, Sadatoshi ^b   Marsella, Rosanna ^a  

^a University of Florida   (United States)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Activated T cells; Atopic dermatitis; Canine; CD25; CD4

Indexed keywords

CHEMOKINE RECEPTOR CCR4; INTERLEUKIN 2 RECEPTOR ALPHA;

ANIMAL; ANIMAL DISEASE; ARTICLE; ATOPIC DERMATITIS; CD4+ T LYMPHOCYTE; CYTOLOGY; DOG; DOG DISEASE; FEMALE; FLOW CYTOMETRY; IMMUNOLOGY; MALE; METABOLISM; PHENOTYPE; PHYSIOLOGY; PYROGLYPHIDAE; TIME;

ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; DERMATITIS, ATOPIC; DOG DISEASES; DOGS; FEMALE; FLOW CYTOMETRY; INTERLEUKIN-2 RECEPTOR ALPHA SUBUNIT; MALE; PHENOTYPE; PYROGLYPHIDAE; RECEPTORS, CCR4; TIME FACTORS;

PYROGLYPHIDAE;

EID: 70349986406     PISSN: 09167250     EISSN: 13477439     Source Type: Journal    
DOI: 10.1292/jvms.71.1177     Document Type: Article

References (30)

1. Akdis, M., Akdis, C.A., Weigl, L., Disch, R. and Blaser, K. 1997. Skin-homing, CLA+ memory T cells are activated in atopic dermatitis and regulate IgE by an IL-13-dominated cytokine pattern: IgG4 co.unter-regulation by CLA- memory T cells. J. Immunol. 159: 4611-4619.
2. Beck, L.A. and Leung, D.M. 2000. Allergen sensitization through the skin induces systemic allergic responses. J. Allergy Clin. Immunol. 106: 258-263.
3. Clark, R.A., Chong, B., Mirchandani, N., Brinster, N.K., Yamanaka, K., Dowgiert, R.K. and Kupper, T.S. 2006. The vast majority of CLA+ T cells are resident in normal skin1. J. Immunol. 176: 4431-4439.
4. Corrigan, C.J. and Kay, A.B. 1991. CD4 T lymphocyte activation in acute severe asthma. Int. Arch. Allergy Appl. Immunol. 94: 270-271.
5. Egli, K.S., Schiessl, B., Roosje, P.J., Seewald, W., Forster, U., Peel, J.E. and Welle, M.M. 2002. Evaluation of the usefulness of sensitization to aeroallergens as a model for canine atopic dermatitis in genetically predisposed Beagles. Am. J. Vet. 63: 1329-1336.
6. Freeman, C.M., Stolberg, V.R., Chiu, B.C., Lukacs, N.W., Kunkel, S.L. and Chensue, S.W. 2006. CCR4 participation in TH Type 1 (mycobacterial) and TH Type 2 (schistosomal) anamnestic pulmonary granulomatous responses1. J. Immunol. 177: 4149-4158.
7. Furue, M., Suglyama, H., Tsukamoto, K., Ohtake, N. and Tamaki, K. 1994. Serum soluble IL-2 receptor (sIL-2R) and eosinophil cationic protein (ECP) levels in atopic dermatitis. J. Dermatol. Sci. 7: 89-95.
8. Hillier, A. and Griggin, C.E. 2001. The ACVD task force on canine atopic dermatitis (I): incidence and prevalence. Vet. Immunol. Immunopathol. 81: 147-152.
9. Iwasaki, T. and Hasegawa, A. 2006. A randomized comparative clinical trial of recombinant canine interferon-γ (KT-100) in atopic dogs using antihistamine as control. Vet. Dermatol. 17: 195-200.
10. Jahnz-Rozyk, K., Targowski, T., Paluchowska, E., Owczarek, W. and Kucharczyk, A. 2005. Serum thymus and activationregulated chemokine, macrophage-derived chemokine and eotaxin as markers of severity of atopic dermatitis. Allergy 60: 685-688.
11. Jang, I., Yang, J., Lee, H., Yi, J., Kim, H., Kim, C. and Kim T. 2000. Clinical improvement and immunohistochemical findings in severe atopic dermatitis treated with interferon gamma. J. Am. Acad. Dermatol. 42: 1033-1040.
12. Jartti, T., Burmeister, K.A., Seroogy, C.M., Jennens-Clough, M.L., Tisler, C.J., Salazar, L.P., Dasilva, D.F., Evans, M.D., Vrtis, R.F., Wallace, P.K., Ruiz-Perez, B., Gangnon, R.E., Lemanske, R.F. Jr. and Gern, J.E. 2007. Association between CD4+CD25high T cells and atopy in children. J. Allergy Clin. Immunol. 120: 177-183.
13. Kakinuma, T., Nakamura, K., Wakugawa, M., Mitsui, H., Tada, Y., Saeki, H., Torii, H., Komine, M., Asahina, A. and Tamaki, K. 2002. Serum macrophage derived chemokine (MDC) levels are closely related with the disease activity of atopic dermatitis. Clin. Exp. Immunol. 127: 270-273.
14. Maeda, S., Ohmori, K., Yasuda, N., Kurata, K., Sakaguchi, M., Masuda, K., Ohno, K. and Tsujimoto, H. 2004. CC chemokine receptor 4-positive cells in the peripheral CD4+ cells in dogs with atopic dermatitis or experimentally sensitized to Japanese cedar pollen. Clin. Exp. Allergy 34: 1467-1473.
15. Maeda, S., Okayama, T., Omori, K., Masuda, K., Sakaguchi, M., Ohno, K. and Tsujimoto, H. 2002. Expression of CC chemokine receptor 4 (CCR4) mRNA in canine atopic skin lesions. Vet. Immunol. Immunopathol. 90: 145-154.
16. Marsella, R. and Olivry, T. 2003. Animal models of atopic dermatitis. Clin. Dermatol. 21: 122-133.
17. Marsella, R., Olivry, T., Nicklin, C. and Lopez, J. 2006. Pilot investigation of a model for canine atopic dermatitis: environ mental house dust mite challenge of high-IgE-producing beagles, mite hypersensitive dogs with atopic dermatitis and normal dogs. Vet. Dermatol. 14: 24-35.
18. Masuda, K. and Yasuda, N. 2008. The antibody against human CD25, ACT-1, recognizes canine T-lymphocytes in the G2/M and G0/G1 phases of the cell cycle during proliferation. J. Vet. Med. Sci. 70: 1285-1287.
19. Musial, J., Milewski, M., Undas, A., Kopinski, P., Duplaga, M. and Szczeklik, A. 1995. Interferon-gamma in the treatment of atopic dermatitis: influence on T-cell activation. Allergy 50: 520-523.
20. Olivry, T., Buckler, K.E., Dunston, S.M., Clarke, K.B. and McCall, C.A. 2002. Positive atopy patch test reactions in IgEhyperresponsive beagle dogs are dependent upon elevated allergen-specific IgE serum levels and are associates with IgEexpressing dendritic cells. Vet. Dermatol. 13: 219.
21. Olivry, T., Marsella, R., Iwasaki, T. and Mueller, R. 2007. Validation of CADESI-03, a severity scale for clinical trials enrolling dogs with atopic dermatitis. Vet. Dermatol. 18: 78-86.
22. Olivry, T., Moore, P.F., Affolter, V.K. and Naydan, D.K. 1996. Langerhans cell hyperplasia and IgE expression in canine atopic dermatitis. Arch. Dermatol. Res. 288: 579-585.
23. Poole, J.A. and Rosenwasser, L.J. 2005. The role of immunoglobulin E and immune inflammation: implications in allergic rhinitis. Cur. Allergy Asthma Rep. 5: 252-258.
24. Reefer, A.J., Satinover, S.M., Solga, M.D., Lannigan, J.A., Nguyen, J.T., Wilson, B.B. and Woodfolk, JA. 2008. Analysis of CD25hiCD4+ "regulatory" T-cell subtypes in atopic dermatitis reveals a novel TH2-like population. J. Allergy Clin. Immunol. 121: 415-422.
25. Schelegle, E.S., Gershwin, L.J., Miller, L.A., Fanucchi, M.V., Van Winkle, L.S., Gerriets, J.P., Walby, W.F., Omlor, A.M., Buckpitt, A.R., Tarkington, B.K., Wong, V.J., Joad, J.P., Pinkerton, K.B., Wu, R., Evans, M.J., Hyde, D.M. and Plopper, C.G. 2001. Allergic asthma induced in rhesus monkeys by house dust mite (Dermatophagoides farinae). Am. J. Pathol. 158: 333-341.
26. Schwartzman, R.M., Massicot, J., Sogn, D.D., Cohen, S.G. 1983. The atopic dog model: report of an attempt to establish a colony. Int. Arch. Allergy. Appl. Immunol. 72: 97-101.
27. Song, T.W., Sohn, M.H., Kim, E.S., Kim, K.W. and Kim, K.E. 2006. Increased serum thymus and activation-regulated chemokine and cutaneous T cell-attracting chemokine levels in children with atopic dermatitis. Clin. Exp. Allergy 36: 346-351.
28. Walker, C., Kägi, M.K., Ingold, P., Braun, P., Blaser, K., Bruijnzeel-Koomen, C.A. and Wüthrich, B. 1993. Atopic dermatitis: correlation of peripheral blood T cell activation, eosinophilia, and serum factors with clinical severity. Clin. Exp. Allergy 23: 145-153.
29. Woitsch, B., Carr, D., Stachel, D., Schmid, I., Weiland, S.K., Fritzsch, C., von Mutius, E. and Kabesch, M. 2004. A comprehensive analysis of interleukin-4 receptor polymorphisms and their association with atopy and IgE regulation in childhood. Int. Arch. Allergy Immunol. 135: 319-324.
30. Xiao, J.Z., Kondo, S., Takahashi, N., Odamaki, T., Iwabuchi, N., Miyaji, K., Iwatsuki, K. and Enomoto, T. 2007. Changes in plasma TARC levels during Japanese cedar pollen season and relationships with symptom development. Int. Arch. Allergy Immunol. 144: 123-127.