Brain-derived neurotrophic factor gene polymorphisms and serum levels in Chinese atopic dermatitis patients

Journal of the European Academy of Dermatology and Venereology

Volumn 23, Issue 11, 2009, Pages 1277-1281

  Ma, L ^a   Gao, X H ^a   Zhao, L P ^b   Di, Z H ^a   McHepange, Uo ^a   Zhang, L ^a   Chen, H D ^a   Wei, H C ^c  

^a CHINA MEDICAL UNIVERSITY   (China)

^b GENERAL HOSPITAL OF NORTHERN THEATER COMMAND   (China)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Atopic dermatitis; Brain derived neurotrophic factor; Polymorphism; Serum level

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR;

ADULT; AGED; ARTICLE; ATOPIC DERMATITIS; CHINESE; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; HUMAN; MAJOR CLINICAL STUDY; MALE; PATHOGENESIS; PRIORITY JOURNAL; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; RISK FACTOR;

BASE SEQUENCE; BRAIN-DERIVED NEUROTROPHIC FACTOR; CASE-CONTROL STUDIES; CHINA; DERMATITIS, ATOPIC; DNA PRIMERS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMANS; MALE; POLYMORPHISM, GENETIC;

EID: 70349966146     PISSN: 09269959     EISSN: 14683083     Source Type: Journal    
DOI: 10.1111/j.1468-3083.2009.03308.x     Document Type: Article

References (26)

1. Leung DY, Bieber T. Atopic dermatitis. Lancet 2003 361 : 151 160. (Pubitemid 36092023)
2. Leung DY, Boguniewicz M, Howell MD et al. New insights into atopic dermatitis. J Clin Invest 2004 113 : 651 657.
3. Leibrock J, Lottspeich F, Hohn A et al. Molecular cloning and expression of brain-derived neurotrophic factor. Nature 1989 341 : 149 152.
4. Vega JA, García-Suárez O, Hannestad J et al. Neurotrophins and the immune system. J Anat 2003 203 : 1 19.
5. Nockher WA, Renz H. Neurotrophins in allergic diseases: from neuronal growth factors to intercellular signaling molecules. J Allergy Clin Immunol 2006 117 : 583 589.
6. Bonini S, Lambiase A, Bonini S et al. Circulating nerve growth factor levels are increased in humans with allergic diseases and asthma. Proc Natl Acad Sci U S A 1996 93 : 10955 10960.
7. Päth G, Braun A, Meents N et al. Augmentation of allergic early-phase reaction by nerve growth factor. Am J Respir Crit Care Med 2002 166 : 818 826.
8. Sanico AM, Stanisz AM, Gleeson TD et al. Nerve growth factor expression and release in allergic inflammatory disease of the upper airways. Am J Respir Crit Care Med 2000 161 : 1631 1635.
9. Raap U, Goltz C, Deneka N et al. Brain-derived neurotrophic factor is increased in atopic dermatitis and modulates eosinophil functions compared with that seen in nonatopic subjects. J Allergy Clin Immunol 2005 115 : 1268 1275.
10. Namura K, Hasegawa G, Egawa M et al. Relationship of serum brain-derived neurotrophic factor level with other markers of disease severity in patients with atopic dermatitis. Clin Immunol 2007 122 : 181 186.
11. Kimata H. Brain-derived neurotrophic factor selectively enhances allergen-specific IgE production. Neuropeptides 2005 39 : 379 383.
12. Timmusk T, Palm K, Metsis M et al. Multiple promoters direct tissue-specific expression of the rat BDNF gene. Neuron 1993 10 : 475 489.
13. Szczepankiewicz A, Breborowicz A, Skibińska M et al. Association analysis of brain-derived neurotrophic factor gene polymorphisms in asthmatic children. Pediatr Allergy Immunol 2007 18 : 293 297.
14. Hoffjan S, Parwez Q, Petrasch-Parwez E et al. Variation in the BDNF and NGFB genes in German atopic dermatitis patients. Mol Cell Probes 2009 23 : 35 38.
15. Williams HC, Burney PG, Hay RJ et al. The U.K. Working Party's diagnostic criteria for atopic dermatitis. I. Derivation of a minimum set of discriminators for atopic dermatitis. Br J Dermatol 1994 131 : 383 396.
16. Williams HC, Burney PG, Strachan D et al. The U.K. Working Party's diagnostic criteria for atopic dermatitis. II. Observer variation of clinical diagnosis and signs of atopic dermatitis. Br J Dermatol 1994 131 : 397 405.
17. Williams HC, Burney PG, Pembroke AC et al. The U.K. Working Party's diagnostic criteria for atopic dermatitis. III. Independent hospital validation. Br J Dermatol 1994 131 : 406 416.
18. Wüthrich B. Clinical aspects epidemiology, and prognosis of atopic dermatitis. Ann Allergy Asthma Immunol 1999 83 : 464 470.
19. Kunugi H, Ueki A, Otsuka M et al. A novel polymorphism of the brain-derived neurotrophic factor (BDNF) gene associated with late-onset Alzheimer's disease. Mol Psychiatry 2001 6 : 83 86.
20. Neves-Pereira M, Mundo E, Muglia P et al. The brain-derived neurotrophic factor gene confers susceptibility to bipolar disorder: evidence from a family-based association study. Am J Hum Genet 2002 71 : 651 655.
21. Egan MF, Weinberger DR, Lu B. Schizophrenia, III: brain-derived neurotropic factor and genetic risk. Am J Psychiatry 2003 160 : 1242.
22. Egan MF, Kojima M, Callicott JH et al. The BDNF val66met polymorphism affects activity-dependent secretion of BDNF and human memory and hippocampal function. Cell 2003 112 : 257 269.
23. Raap U, Werfel T, Goltz C et al. Circulating levels of brain-derived neurotrophic factor correlate with disease severity in the intrinsic type of atopic dermatitis. Allergy 2006 61 : 1416 1418.
24. Lommatzsch M, Schloetcke K, Klotz J et al. Brain-derived neurotrophic factor in platelets and airflow limitation in asthma. Am J Respir Crit Care Med 2005 171 : 115 120.
25. Virchow JC, Julius P, Lommatzsch M et al. Neurotrophins are increased in bronchoalveolar lavage fluid after segmental allergen provocation. Am J Respir Crit Care Med 1998 158 : 2002 2005.
26. Hon KL, Lam MC, Wong KY et al. Pathophysiology of nocturnal scratching in childhood atopic dermatitis: the role of brain-derived neurotrophic factor and substance P. Br J Dermatol 2007 157 : 922 925.