On the function and structure of synthetically modified porins

Angewandte Chemie - International Edition

Volumn 48, Issue 26, 2009, Pages 4853-4857

  Reitz, Simon ^a   Cebi, Menekse ^a   Reiß, Philipp ^a   Studnik, Gregor ^a   Linne, Uwe ^a   Koert, Ulrich ^a   Essen, Lars Oliver ^a  

^a PHILIPPS UNIVERSITY MARBURG   (Germany)

Author keywords

Crown compounds; Ion channels; Ion current modulators; Native chemical ligation; Porin structures

Indexed keywords

CONFORMATIONAL HETEROGENEITY; CROWN COMPOUNDS; HYBRID CHANNELS; ION CHANNEL; ION CHANNELS; LARGE PORES; NATIVE CHEMICAL LIGATION; NON-COVALENT INTERACTION; PORIN STRUCTURES;

CHEMICAL COMPOUNDS; CROWN ETHERS; ETHERS; IONS; MODULATION;

MODULATORS;

CROWN ETHER; ION CHANNEL; OUTER MEMBRANE PROTEIN F; PORIN;

CHEMISTRY; PROTEIN CONFORMATION; X RAY CRYSTALLOGRAPHY;

CROWN ETHERS; CRYSTALLOGRAPHY, X-RAY; ION CHANNELS; PORINS; PROTEIN CONFORMATION;

EID: 70349946956     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200900457     Document Type: Article

References (26)

1. a) H. Bayley, L. Jayasinghe, Mol. Membr. Biol. 2004 21, 209-220;
2. b) M. R. Banghart, M. Volgraf, D. Trauner, Biochemistry 2006 45, 15129-15141;
3. L.-O. Essen, U Koert, Ann. Rep. RSC 2008 704, 165-188.
4. a) F. Valiyaveetil, M. Sekedat, T. W. Muir, R. MacKinnon, Angew. Chem. 2004 776, 2558-2561;
5. Angew. Chem. Int. Ed. 2004 43, 2504-2507;
6. b) F. Valiyaveetil, M. Sekedat, T. W. Muir, R. MacKinnon, J. Am. Chem. Soc. 2006 725, 11591-11599;
7. c) A. Koçer, M. Walko, W. Meijberg, B. L. Feringa, Science 2005 309, 755-758;
8. d) A. Koçer, M. Walko, E. Bulten, E. Halza, B. L. Feringa, Angew. Chem. 2006 118, 3198-3202;
9. Angew. Chem.Int. Ed. 2006 45, 3126-3130;
10. e) M. Banghart, K. Borges, E. Isacoff, D. Trauner, R. H. Kramer, Nat. Neurosci. 2004 7, 1381-1386.
11. a) L. Q. Gu., O. Braha, S. Conlan, H. Bayley, Nature 1999 398, 686-690;
12. b) H. C. Wu, Y. Astier, G. Maglia, E. Mikhailova, H. Bayley, J. Am, Chem. Soc. 2007 129, 16142-16148.
13. Bacterial and Eucaryotic Porins (Ed.: R. Benz), Wiley-VCH, Weinheim, 2004.
14. a) R. M. Garavito, J.P. Rosenbusch, J. Cell Biol. 1980 86, 327-329;
15. b) A. Engel, A. Massalski, H. Schindler, D. L. Dorset, J.P. Rosenbusch, Nature 1985 317, 643-645;
16. c) S.W. Cowan, T. Schirmer, G. Rummel, M. Steiert, R. Gosh, R. A. Pauptit, J.N. Jansonius, J.P. Rosenbusch, Nature 1992 358, 727-733.
17. a) T. Surrey, F. Jähnig, Proc. Natl. Acad. Sci. USA 1992 89, 7457-7461;
18. b)T. Surrey, A. Schmid, F. Jähnig, Biochemistry 1996 35, 2283-2288.
19. A. Alcaraz, E. M. Nestorovich, M. Aguilella-Arzo, V. M. Aguilella, S. M. Bezrukov, Biophys. J. 2004 87, 943-957.
20. A. Engel, A. Massalski, H. Schindler, D. L. Dorset, J.P. Rose-nbusch, Nature 1985 317, 643-645.
21. E. Yamashita, M. V. Zhalnina, S. D. Zakharov, O. Sharma, W. A. Cramer, EMBO J. 2008 27, 2171-2180.
22. a) R. Hilgenfeld, W. Saenger, Angew. Chem. 1981 93, 1082-1085;
23. Angew. Chem. Int. Ed. Engl. 1981 20, 1045 -1046;
24. b) A. N. Chekhlov, Russ. J. Coord. Chem. 2000 27, 771-775;
25. c) J. W. Steed, Coord Chem. Rev. 2001 215, 171-221.
26. M. Chen, S. Khalid, M. S. P. Sansom, H. Bayley, Proc. Natl. Acad.Sci. USA 2008 105, 6272-6277.