Autocrine semaphorin3A stimulates alpha2 beta1 integrin expression/function in breast tumor cells

Breast Cancer Research and Treatment

Volumn 118, Issue 1, 2009, Pages 197-205

  Pan, Hongjie ^a   Wanami, Luke S ^a   Dissanayake, Thusitha R ^a   Bachelder, Robin E ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Breast tumor; Integrin; Migration; Neuropilin 1; Semaphorin3A

Indexed keywords

ACTIN; COLLAGEN TYPE 1; GLYCOGEN SYNTHASE KINASE 3; NEUROPILIN 1; NEUTRALIZING ANTIBODY; SEMAPHORIN 3A; VERY LATE ACTIVATION ANTIGEN 2;

ARTICLE; AUTOCRINE EFFECT; BREAST TUMOR; CANCER INVASION; CELL ADHESION; CELL MIGRATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

ADENOCARCINOMA; ANTIBODIES, NEUTRALIZING; AUTOCRINE COMMUNICATION; BREAST NEOPLASMS; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; COLLAGEN TYPE I; CYTOSKELETON; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INTEGRIN ALPHA2BETA1; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; NEOPLASM PROTEINS; NEUROPILIN-1; RECOMBINANT PROTEINS; SEMAPHORIN-3A;

EID: 70349941415     PISSN: 01676806     EISSN: 15737217     Source Type: Journal    
DOI: 10.1007/s10549-008-0179-y     Document Type: Article

References (26)

1. Z He M Tessier-Lavigne 1997 Neuropilin is a receptor for the axonal chemorepellent semaphorin III Cell 90 4 739 751 10.1016/S0092-8674(00)80534-6 10.1016/S0092-8674(00)80534-6 1:CAS:528:DyaK2sXlvFKmurw%3D 9288753 (Pubitemid 27357965)
2. AL Kolodkin DV Levengood EG Rowe YT Tai RJ Giger DD Ginty 1997 Neuropilin is a semaphorin III receptor Cell 90 4 753 762 10.1016/S0092-8674(00)80535-8 10.1016/S0092-8674(00)80535-8 1:CAS:528:DyaK2sXlvFKmur0%3D 9288754 (Pubitemid 27357966)
3. HQ Miao S Soker L Feiner JL Alonso JA Raper M Klagsbrun 1999 Neuropilin-1 mediates collapsin-1/semaphorin III inhibition of endothelial cell motility: functional competition of collapsin-1 and vascular endothelial growth factor-165 J Cell Biol 146 1 233 242 10.1083/jcb.146.1.233 10.1083/jcb.146.1.233 1:CAS:528:DyaK1MXksFCjs7c%3D 10402473 (Pubitemid 29349977)
4. G Serini D Valdembri S Zanivan G Morterra C Burkhardt F Caccavari, et al. 2003 Class 3 semaphorins control vascular morphogenesis by inhibiting integrin function Nature 424 6947 391 397 10.1038/nature01784 10.1038/nature01784 1:CAS:528:DC%2BD3sXls1aqsb8%3D 12879061 (Pubitemid 36917481)
5. RE Bachelder EA Lipscomb X Lin MA Wendt NH Chadborn BJ Eickholt, et al. 2003 Competing autocrine pathways involving alternative neuropilin-1 ligands regulate chemotaxis of carcinoma cells Cancer Res 63 17 5230 5233 1:CAS:528:DC%2BD3sXntlektL0%3D 14500350
6. MJ Elices ME Hemler 1989 The human integrin VLA-2 is a collagen receptor on some cells and a collagen/laminin receptor on others Proc Natl Acad Sci USA 86 24 9906 9910 10.1073/pnas.86.24.9906 10.1073/pnas.86.24.9906 1:CAS:528:DyaK3cXps1WmsA%3D%3D 2557634 (Pubitemid 20030743)
7. J Chen TG Diacovo DG Grenache SA Santoro MM Zutter 2002 The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis Am J Pathol 161 1 337 344 1:CAS:528:DC%2BD38Xlsl2ksLo%3D 12107118
8. MM Faraldo MA Deugnier M Lukashev JP Thiery MA Glukhova 1998 Perturbation of beta1-integrin function alters the development of murine mammary gland EMBO J 17 8 2139 2147 10.1093/emboj/17.8.2139 10.1093/emboj/17.8.2139 1:CAS:528:DyaK1cXivFOmsLw%3D 9545227 (Pubitemid 28171899)
9. MJ Naylor N Li J Cheung ET Lowe E Lambert R Marlow, et al. 2005 Ablation of beta1 integrin in mammary epithelium reveals a key role for integrin in glandular morphogenesis and differentiation J Cell Biol 171 4 717 728 10.1083/jcb.200503144 10.1083/jcb.200503144 1:CAS:528:DC%2BD2MXht1KgtL3L 16301336 (Pubitemid 41668730)
10. S Maschler G Wirl H Spring DV Bredow I Sordat H Beug, et al. 2005 Tumor cell invasiveness correlates with changes in integrin expression and localization Oncogene 24 12 2032 2041 10.1038/sj.onc.1208423 10.1038/sj.onc.1208423 1:CAS:528:DC%2BD2MXitlCmsrc%3D 15688013 (Pubitemid 40516196)
11. MM Zutter HR Krigman SA Santoro 1993 Altered integrin expression in adenocarcinoma of the breast. Analysis by in situ hybridization Am J Pathol 142 5 1439 1448 1:STN:280:DyaK3s3mtlaisw%3D%3D 8388172
12. MM Zutter G Mazoujian SA Santoro 1990 Decreased expression of integrin adhesive protein receptors in adenocarcinoma of the breast Am J Pathol 137 4 863 870 1:STN:280:DyaK3M%2Fit12rsQ%3D%3D 2221016
13. GP Gui JR Puddefoot GP Vinson CA Wells R Carpenter 1995 In vitro regulation of human breast cancer cell adhesion and invasion via integrin receptors to the extracellular matrix Br J Surg 82 9 1192 1196 10.1002/bjs.1800820914 10.1002/bjs.1800820914 1:STN:280:DyaK28%2FjtVCitQ%3D%3D 7551993
14. A Lochter M Navre Z Werb MJ Bissell 1999 Alpha1 and alpha2 integrins mediate invasive activity of mouse mammary carcinoma cells through regulation of stromelysin-1 expression Mol Biol Cell 10 2 271 282 1:CAS:528: DyaK1MXitFGgtLk%3D 9950676
15. PJ Keely AM Fong MM Zutter SA Santoro 1995 Alteration of collagen-dependent adhesion, motility, and morphogenesis by the expression of antisense alpha 2 integrin mRNA in mammary cells J Cell Sci 108 Pt 2 595 607 1:CAS:528:DyaK2MXktFSjs7k%3D 7769004
16. MM Zutter SA Santoro WD Staatz YL Tsung 1995 Re-expression of the alpha 2 beta 1 integrin abrogates the malignant phenotype of breast carcinoma cells Proc Natl Acad Sci USA 92 16 7411 7415 10.1073/pnas.92.16.7411 10.1073/pnas.92.16.7411 1:CAS:528:DyaK2MXntlKmtbY%3D 7638207
17. BJ Eickholt FS Walsh P Doherty 2002 An inactive pool of GSK-3 at the leading edge of growth cones is implicated in semaphorin 3A signaling J Cell Biol 157 2 211 217 10.1083/jcb.200201098 10.1083/jcb.200201098 1:CAS:528:DC%2BD38XivFKktL4%3D 11956225 (Pubitemid 34839818)
18. MP Coghlan AA Culbert DA Cross SL Corcoran JW Yates NJ Pearce, et al. 2000 Selective small molecule inhibitors of glycogen synthase kinase-3 modulate glycogen metabolism and gene transcription Chem Biol 7 10 793 803 10.1016/S1074-5521(00)00025-9 10.1016/S1074-5521(00)00025-9 1:CAS:528: DC%2BD3cXotVWitrs%3D 11033082
19. MS Roberts AJ Woods TC Dale P Van Der Sluijs JC Norman 2004 Protein kinase B/Akt acts via glycogen synthase kinase 3 to regulate recycling of alpha v beta 3 and alpha 5 beta 1 integrins Mol Cell Biol 24 4 1505 1515 10.1128/MCB.24.4.1505-1515.2004 10.1128/MCB.24.4.1505-1515.2004 1:CAS:528:DC%2BD2cXhtFOjsb8%3D 14749368 (Pubitemid 38167074)
20. PA DiMilla JA Stone JA Quinn SM Albelda DA Lauffenburger 1993 Maximal migration of human smooth muscle cells on fibronectin and type IV collagen occurs at an intermediate attachment strength J Cell Biol 122 3 729 737 10.1083/jcb.122.3.729 10.1083/jcb.122.3.729 1:CAS:528:DyaK3sXkvFaht7Y%3D 8335696
21. L Lynch PI Vodyanik D Boettiger MA Guvakova 2005 Insulin-like growth factor I controls adhesion strength mediated by alpha5 beta1 integrins in motile carcinoma cells Mol Biol Cell 16 1 51 63 10.1091/mbc.E04-05-0399 10.1091/mbc.E04-05-0399 1:CAS:528:DC%2BD2MXhvFeruw%3D%3D 15509657 (Pubitemid 40024290)
22. M Murga O Fernandez-Capetillo G Tosato 2005 Neuropilin-1 regulates attachment in human endothelial cells independently of vascular endothelial growth factor receptor-2 Blood 105 5 1992 1999 10.1182/blood-2004-07-2598 10.1182/blood-2004-07-2598 1:CAS:528:DC%2BD2MXitVOnsLk%3D 15522955 (Pubitemid 40731783)
23. H Kashiwagi M Shiraga H Kato T Kamae N Yamamoto S Tadokoro, et al. 2005 Negative regulation of platelet function by a secreted cell repulsive protein, semaphorin 3A Blood 106 3 913 921 10.1182/blood-2004-10-4092 10.1182/blood-2004-10-4092 1:CAS:528:DC%2BD2MXntVSnurY%3D 15831706 (Pubitemid 41076433)
24. Y Lepelletier S Smaniotto R Hadj-Slimane DM Villa-Verde AC Nogueira M Dardenne, et al. 2007 Control of human thymocyte migration by neuropilin-1/semaphorin-3A-mediated interactions Proc Natl Acad Sci USA 104 13 5545 5550 10.1073/pnas.0700705104 10.1073/pnas.0700705104 1:CAS:528: DC%2BD2sXkt1Sisr0%3D 17369353 (Pubitemid 47175717)
25. JG Herman GG Meadows 2007 Increased class 3 semaphorin expression modulates the invasive and adhesive properties of prostate cancer cells Int J Oncol 30 5 1231 1238 1:CAS:528:DC%2BD2sXlsVCms7c%3D 17390026
26. V Castellani A Chedotal M Schachner C Faivre-Sarrailh G Rougon 2000 Analysis of the L1-deficient mouse phenotype reveals cross-talk between Sema3A and L1 signaling pathways in axonal guidance Neuron 27 2 237 249 10.1016/S0896-6273(00)00033-7 10.1016/S0896-6273(00)00033-7 1:CAS:528: DC%2BD3cXmsVWmt74%3D 10985345