Binding kinetics and activity of human poly (ADP-ribose) polymerase-1 on oligo-deoxyribonucleotide substrates

Journal of Molecular Recognition

Volumn 22, Issue 6, 2009, Pages 446-452

  Jorgensen, Timothy J ^a   Chen, Kevin ^a   Chasovskikh, Sergey ^a   Roy, Rabindra ^a   Dritschilo, Anatoly ^a   Üren, Aykut ^a  

^a GEORGETOWN UNIVERSITY   (United States)

Author keywords

Binding kinetics; DNA double strand breaks; DNA repair; Non homologous end joining; PARP 1; Poly(ADP ribose) polymerase 1; Poly(ADP ribosyl)ation; Surface plasmon resonance

Indexed keywords

DNA; LIGAND; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; OLIGONUCLEOTIDE; OXYGEN; PARP1 PROTEIN, HUMAN; SINGLE STRANDED DNA;

ARTICLE; CHEMISTRY; COMPUTER PROGRAM; DNA DAMAGE; DNA REPAIR; HUMAN; KINETICS; PHYSIOLOGY; PROTEIN BINDING; SURFACE PLASMON RESONANCE;

DNA; DNA DAMAGE; DNA REPAIR; DNA, SINGLE-STRANDED; HUMANS; KINETICS; LIGANDS; OLIGONUCLEOTIDES; OXYGEN; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; SOFTWARE; SURFACE PLASMON RESONANCE;

MAMMALIA;

EID: 70349914019     PISSN: 09523499     EISSN: 10991352     Source Type: Journal    
DOI: 10.1002/jmr.962     Document Type: Article

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