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70349918094
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Bromide 32 was obtained from a route identical the one shown in Scheme 5, the only difference being the use of Br-BBN. For further information, see the Supporting Information
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Bromide 32 was obtained from a route identical the one shown in Scheme 5, the only difference being the use of Br-BBN. For further information, see the Supporting Information.
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34
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70349909818
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When tris(trimethylsilyl)silane (TTMSS) was used as reducing agent instead of tributylstannane, the radical cyclization proceeded smoothly, but analysis of the product revealed that both the exo-methylene and methyl ketone groups had isomerized during the reaction to a trisubstituted endoolefln and an enaio-ketone, respectively
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When tris(trimethylsilyl)silane (TTMSS) was used as reducing agent instead of tributylstannane, the radical cyclization proceeded smoothly, but analysis of the product revealed that both the exo-methylene and methyl ketone groups had isomerized during the reaction to a trisubstituted endoolefln and an enaio-ketone, respectively.
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29044439970
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The use of benzoquinone was necessary to suppress competing isomerization of the allyl group
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The use of benzoquinone was necessary to suppress competing isomerization of the allyl group. Hong, S. H.: Sanders, D. P.; Lee, C. W.: Grubbs, R. H. J. Am. Chem. Soc. 2005, 127, 17160-1716L
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