fMRI revealed neural substrate for reversible working memory dysfunction in subclinical hypothyroidism

Brain

Volumn 129, Issue 11, 2006, Pages 2923-2930

  Zhu, De Fa ^a   Wang, Zhao Xin ^b,d   Zhang, Da Ren ^b   Pan, Zhong Lin ^c   He, Sheng ^e   Hu, Xiao Ping ^f   Chen, Xiang Chuan ^b,g   Zhou, Jiang Ning ^b,g  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

^c The 105th Hospital of PLA   (China)

^d SHANTOU UNIVERSITY MEDICAL COLLEGE   (China)

^e UNIVERSITY OF MINNESOTA   (United States)

^f EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Frontal cortex; Functional MRI (fMRI); L thyroxine treatment; Subclinical hypothyroidism (SCH); Working memory

Indexed keywords

LEVOTHYROXINE;

ADOLESCENT; ADULT; ARTICLE; BRAIN FUNCTION; BRAIN REGION; CINGULATE GYRUS; CLINICAL ARTICLE; CONTROLLED STUDY; EUTHYROIDISM; FEMALE; FRONTAL CORTEX; FUNCTIONAL MAGNETIC RESONANCE IMAGING; HUMAN; HYPERTHYROIDISM; HYPOTHYROIDISM; MALE; MEMORY; MEMORY DISORDER; MENTAL PERFORMANCE; MENTAL TASK; MOTOR CORTEX; OXYGEN BLOOD LEVEL; PARIETAL LOBE; PREFRONTAL CORTEX; PREMOTOR CORTEX; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; WORKING MEMORY;

ADOLESCENT; ADULT; BRAIN MAPPING; FEMALE; FOLLOW-UP STUDIES; FRONTAL LOBE; HUMANS; HYPOTHYROIDISM; MAGNETIC RESONANCE IMAGING; MALE; MEMORY DISORDERS; MEMORY, SHORT-TERM; MENTAL RECALL; NEUROPSYCHOLOGICAL TESTS; OXYGEN; PSYCHOMETRICS; THYROID HORMONES; THYROXINE;

EID: 33750590558     PISSN: 00068950     EISSN: 14602156     Source Type: Journal    
DOI: 10.1093/brain/awl215     Document Type: Article

References (51)

1. Anderson GW. Thyroid hormones and the brain. Front Neuroendocrinol 2001; 22: 1-17.
2. Arem R, Escalante D. Subclinical hypothyroidism: epidemiology, diagnosis, and significance. St Louis: Mosby-Year Book Inc; 1996.
3. Ayala AR, Danese MD, Ladenson PW. When to treat mild hypothyroidism. Endocrinol Metab Clin North Am 2000; 29: 399-415.
4. Baddeley A. Working memory. Science 1992; 256: 556-9.
5. Baldini IM, Vita A, Mauri MC, Amodei V, Carrisi M, Bravin S, et al. Psychopathological and cognitive features in subclinical hypothyroidism. Prog Neuropsychopharmacol Biol Psychiatry 1997; 21: 925-35.
6. Bono G, Fancellu R, Blandini F, Santoro G, Mauri M. Cognitive and affective status in mild hypothyroidism and interactions with L-thyroxine treatment. Acta Neurol Scand 2004; 110: 59-66.
7. Braver TS, Cohen JD, Nystrom LE, Jonides J, Smith EE, Noll DC. A parametric study of prefrontal cortex involvement in human working memory. Neuroimage 1997; 5: 49-62.
8. Bulens C. Neurologic complications of hyperthyroidism: remission of spastic paraplegia, dementia, and optic neuropathy. Arch Neurol 1981; 38: 669-70.
9. Burmeister LA, Ganguli M, Dodge HH, Toczek T, DeKosky ST, Nebes RD. Hypothyroidism and cognition: preliminary evidence for a specific defect in memory. Thyroid 2001; 11: 1177-85.
10. Callicott JH, Mattay VS, Bertolino A, Finn K, Coppola R, Frank JA, et al. Physiological characteristics of capacity constraints in working memory as revealed by functional MRI. Cereb Cortex 1999; 9: 20-6.
11. Callicott JH, Bertolino A, Mattay VS, Langheim FJ, Duyn J, Coppola R, et al. Physiological dysfunction of the dorsolateral prefrontal cortex in schizophrenia revisited. Cereb Cortex 2000; 10: 1078-92.
12. Chayer C, Freedman M. Frontal lobe functions. Curr Neurol Neurosci Rep 2001; 1: 547-52.
13. Chu JW, Crapo LM. The treatment of subclinical hypothyroidism is seldom necessary. J Clin Endocrinol Metab 2001; 86: 4591-9.
14. Cohen JD, Perlstein WM, Braver TS, Nystrom LE, Noll DC, Jonides J, et al. Temporal dynamics of brain activation during a working memory task. Nature 1997; 386: 604-8.
15. Col NF, Surks MI, Daniels GH. Subclinical thyroid disease: clinical applications. JAMA 2004; 291: 239-43.
16. Cooper DS. Subclinical thyroid disease: a clinician's perspective. Ann Intern Med 1998; 129: 135-8.
17. Cooper DS. Clinical practice. Subclinical hypothyroidism. N Engl JMed 2001; 345: 260-5.
18. Cooper DS. Hyperthyroidism. Lancet 2003; 362: 459-68.
19. Cox RW. AFNI: software for analysis and visualization of functional magnetic resonance neuroimages. Comput Biomed Res 1996; 29: 162-73.
20. Cunha UG. An investigation of dementia among elderly outpatients. Acta Psychiatr Scand 1990; 82: 261-3.
21. del Ser Quijano T, Delgado C, Martinez ES, Vazquez C. [Cognitive deficiency in mild hypothyroidism]. Neurologia 2000; 15: 193-8.
22. Dugbartey AT. Neurocognitive aspects of hypothyroidism. Arch Intern Med 1998; 158: 1413-18.
23. Evered DC, Ormston BJ, Smith PA, Hall R, Bird T. Grades of hypothyroidism. Br Med J 1973; 1: 657-62.
24. Fletcher PC, Henson RN. Frontal lobes and human memory: insights from functional neuroimaging. Brain 2001; 124: 849-81.
25. Gong Y, Wang D, Deng J. Handbook of Wechsler Memory Scale-Revised. ChangSha, China: Bulletin of Hunan Medical College; 1989.
26. Gussekloo J, van Exel E, de Craen AJ, Meinders AE, Frolich M, Westendorp RG. Thyroid status, disability and cognitive function, and survival in old age. JAMA 2004; 292: 2591-9.
27. Honey GD, Fu CH, Kim J, Brammer MJ, Croudace TJ, Suckling J, et al. Effects of verbal working memory load on corticocortical connectivity modeled by path analysis of functional magnetic resonance imaging data. Neuroimage 2002; 17: 573-82.
28. Jansma JM, Ramsey NF, Coppola R, Kahn RS. Specific versus nonspecific brain activity in a parametric N-back task. Neuroimage 2000; 12: 688-97.
29. Kalmijn S, Mehta KM, Pols HA, Hofman A, Drexhage HA, Breteler MM. Subclinical hyperthyroidism and the risk of dementia. The Rotterdam study. Clin Endocrinol (Oxf) 2000; 53: 733-7.
30. Loosen PT. Effects of thyroid hormones on central nervous system in aging. Psychoneuroendocrinology 1992; 17: 355-74.
31. Mennemeier M, Garner RD, Heilman KM. Memory, mood and measurement in hypothyroidism. J Clin Exp Neuropsychol 1993; 15: 822-31.
32. Monzani F, Del Guerra P, Caraccio N, Pruneti CA, Pucci E, Luisi M, et al. Subclinical hypothyroidism: neurobehavioral features and beneficial effect of L-thyroxine treatment. Clin Investig 1993; 71: 367-71.
33. Nystrom LE, Braver TS, Sabb FW, Delgado MR, Noll DC, Cohen JD. Working memory for letters, shapes, and locations: fMRI evidence against stimulus-based regional organization in human prefrontal cortex. Neuroimage 2000; 11: 424-46.
34. Owen AM, McMillan KM, Laird AR, Bullmore E. N-back working memory paradigm: a meta-analysis of normative functional neuroimaging studies. Hum Brain Mapp 2005; 25: 46-59.
35. Paulesu E, Frith CD, Frackowiak RS. The neural correlates of the verbal component of working memory. Nature 1993; 362: 342-5.
36. Perlstein WM, Carter CS, Noll DC, Cohen JD. Relation of prefrontal cortex dysfunction to working memory and symptoms in schizophrenia. Am J Psychiatry 2001; 158: 1105-13.
37. Prinz PN, Scanlan JM, Vitaliano PP, Moe KE, Borson S, Toivola B, et al. Thyroid hormones: positive relationships with cognition in healthy, euthyroid older men. J Gerontol A Biol Sci Med Sci 1999; 54: M111-16.
38. Roberts CG, Ladenson PW. Hypothyroidism. Lancet 2004; 363: 793-803.
39. Schlinger JL, Goichot B, Vinzio S, Perrin AE, Grunenberger F, Sapin R. Subclinical hypothyroidism, towards the end of a controversy. Presse Med 2003; 32: 1760-5.
40. Schlote B, Nowotny B, Schaaf L, Kleinbohl D, Schmidt R, Teuber J, et al. Subclinical hyperthyroidism: physical and mental state of patients. Eur Arch Psychiatry Clin Neurosci 1992; 241: 357-64.
41. Surks MI, Ortiz E, Daniels GH, Sawin CT, Col NF, Cobin RH, et al. Subclinical thyroid disease: scientific review and guidelines for diagnosis and management. JAMA 2004; 291: 228-38.
42. Smith CL, Granger CV. Hypothyroidism producing reversible dementia. A challenge for medical rehabilitation. Am J Phys Med Rehabil 1992; 71: 28-30.
43. Smith EE, Jonides J. Working memory: a view from neuroimaging. Cognit Psychol 1997; 33: 5-42.
44. Smith EE, Jonides J. Neuroimaging analyses of human working memory. Proc Natl Acad Sci USA 1998; 95: 12061-8.
45. Stern RA, Robinson B, Thorner AR, Arruda JE, Prohaska ML, Prange AJ Jr. A survey study of neuropsychiatric complaints in patients with Graves' disease. J Neuropsychiatry Clin Neurosci 1996; 8: 181-5.
46. Talairach J, Tournoux P. Co-planar stereotaxic atlas of the human brain. New York: Thieme Medical Publishers; 1988.
47. Timiras PS, Nzekwe EU. Thyroid hormones and nervous system development. Biol Neonate 1989; 55: 376-85.
48. Volpato S, Guralnik JM, Fried LP, Remaley AT, Cappola AR, Launer LJ. Serum thyroxine level and cognitive decline in euthyroid older women. Neurology 2002; 58: 1055-61.
49. Wechsler D. Wechsler Memory Scale-Revised. New York: Psychological Corporation; 1987.
50. Wickelgren I. Getting a grasp on working memory. Science 1997; 275: 1580-2.
51. Zeitlhofer J, Saletu B, Stary J, Ahmadi R. Cerebral function in hyperthyroid patients. Psychopathology, psychometric variables, central arousal and time perception before and after thyreostatic therapy. Neuropsychobiology 1984; 11: 89-93.