Antinociceptive effects of Newbouldia laevis (P. Beauv.) stem bark extract in a rat model

Pharmacognosy Magazine

Volumn 4, Issue 17, 2009, Pages 49-54

  Ainooson, George K ^a   Woode, Eric ^a   Obiri, David D ^a   Koffour, George A ^a  

^a KWAME NKRUMAH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Ghana)

Author keywords

Anti inflammatory activity; Anti nociceptive activity; Newbouldia laevis

Indexed keywords

DICLOFENAC; MORPHINE; NEWBOULDIA LAEVIS EXTRACT; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTINOCICEPTION; ARTICLE; BARK; BIGNONIACEAE; DOSE RESPONSE; DRUG EFFECT; DRUG EFFICACY; DRUG POTENCY; DRUG RESPONSE; NEUROPATHIC PAIN; NEWBOULDIA LAEVIS; NONHUMAN; RAT; CONTROLLED STUDY; PLANT STEM;

EID: 70349842029     PISSN: 09731296     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (35)

1. N.R. Mshana,, K. Abbiw, I. Addae-Mensah, E. Adjanohoun, M.R.A. Ahyi, J.A. Ekpere, E.G. Enow-Orock, Z.O. Gbile, G.K. Noamesi, M.A. Odei, H. Odunlami, A.A. Oteng-Yeboah, K. Sarpong, A. Soforowa and A.N. Tackie Traditional Medicine and Pharmacopoeia. Contribution to the Revision of Ethnobotanical and Floristic Studies in Ghana. Organization of African Unity/Scientific, Technical & Research Commision: Accra, 2000.
2. O.A. Olajide, S.O. Awe and J.M. Makinde. Pharmacological studies on Newbouldia laevis stem bark. Fitoterapia 68(5): 439-443 (1997).
3. E. Woode, M. Duwiejua, C. Ansah, G. A. Koffuor, D. D. Obiri, F. A. Amissah, and G. K. Ainooson. Antiinflammatory and analgesic effects of Newbouldia laevis stem bark extract. Proceedings of the 2nd Scientific Meeting Western Africa Network of Natural Products Research Scientists (Wannpres), Elmina, Ghana, 1st-4th August, 2006.
4. E. Woode, M. Duwiejua, C. Ansah, G. A. Koffuor, D. D. Obiri, A. Y. Mensah, and G. K. Ainooson. Antioxidant properties of Newbouldia Iaevis stem bark extract. Proceedings of the 2nd Scientific Meeting Western Africa Network of Natural Products Research Scientists (Wannpres)., Elmina, Ghana, 1st-4th August, 2006.
5. D. Dubuisson and S.G. Dennis. The formalin test: a quantitave study of the analgesic effects of morphine, meperidine, and brain stem stimulation in rats and cats. Pain 4: 161-174 (1977).
6. A.B. Malmberg and T.L. Yaksh. Antinociceptive Actions of Spinal Nonsteroidal Antiinflammatory Agents on the Formalin Test in the Rat1. JPET 263(1): 136-146 (1992).
7. L. Bardin and F.C. Colpaert. Role of spinal 5-HT1A receptors in morphine analgesia and tolerance in rats. Eur J Pain 8: 253-261 (2004).
8. E.J. Chesler, J. Ritchie, A. Kokayeff, W.R. Lariviere, S.G. Wilson and J.S. Mogil. Genotype-dependence of gabapentin and pregabalin sensitivity: the pharmacogenetic mediation of analgesia is specific to the type of pain being inhibited. Pain 106: 325-335 (2003).
9. K. Hayashida, T. Takeuchi, H. Shimizu, K. Ando and E. Harada. Lactofering enhances opioid-mediated analgesia via nitric oxide in the rat spinal cord. Am J Physiol - Regul Integr and Comp Physiol 285: R306-R312 (2003).
10. J.R. Miller. GraphPad Version 4.0. Step-by-Step Examples. GraphPad Software Inc., San Diego, CA (2003).
11. H.J. Motulsky and A. Christopoulos. Fitting model to biological data using linear and nonlinear regression. A practical guide to curve fitting. GraphPad Software Inc.: San Diego, CA, (2003).
12. H. Wheeler-Aceto, F. Porreca and A. Cowan The rat formalin test: comparison of noxious agents. Pain 40: 229-238 (1990).
13. Y.X. Wang, S.S. Bowersox, M. Pettus and D. Gao. Antinociceptive Properties of Fenfluramine, a Serotonin Reuptake Inhibitor, in a Rat Model of Neuropathy. JPET 291(3): 1008-1016 (1999).
14. T.T. Chau. Analgesic Testing In Animal Models. In: Pharmacological Methods in the Control of Inflammation J.Y. Chang, A.J Lewis (eds), pp 195-212. New York: Alan R. Liss, Inc., 1989.
15. S.H. Ferreira, B.B. Lorrenzetti and F.M.A. Correa. Central and peripheral antialgesic action of aspirin like drugs. Eur J Pharmacol 53: 39-48 (1978).
16. D. Le Bars, G. Manuela and S.W. Cadden. Animal Models of Nociception. Pharmacol Rev 53: 597-652 (2001).
17. L.V. Costa-Lotufo, D.F. De Lucena, M. Andrade-Neto, J.N.S. Bezerra, L.K.A.M. Leal, F.C.F. De Sousa and G.S. De Barros Viana. Analgesic, Antiinflammatory and Central Depressor Effects of the Hydroalcoholic Extract and Fractions from Aeolanthus suaveolens. Biol. Pharm. Bull 27(6): 821-824 (2004).
18. S.M.M. Vasconcelos, G.R. Oliveira, M.M. De Carvalho, A.C.P. Rodrigues, E.R. Silveira, M.M.F. Fonteles, F.C.F. Sousa and G.S.B. Viana. Antinociceptive Activities of the Hydroalcoholic Extracts from Erythrina velutina and Erythrina mulungu in Mice. Biol. Pharm. Bull 26(7): 946-949 (2003).
19. K. Vissers, V. Hoffmann, F. Geenen, R. Biermans and T. Meert. Is the Second Phase of the Formalin Test Useful to Predict Activity in Chronic Constriction Injury Models ? A Pharmacological Comparison in Different Species. Pain Practice 3(4): 298-309 (2003).
20. F.V. Abbott. Peripheral and central antinociceptive actions of ethylketocyclazocine in the formalin test. Eur J Pharmacol 152: 93-100 (1988).
21. C. Courteix, P. Bourget, F. Caussade, M. Bardin, F. Coudore, J. Fialip and A. Eschalier. Is the Reduced Efficacy of Morphine in Diabetic Rats Caused by Alterations of Opiate Receptors or of Morphine Pharmacokinetics. JPET 285(1): 63-70 (1998).
22. J. Szolcsanyi, K. Bolcskei, A. Szabo, E. Pinter, G. Petho, K. Elekes, R. Borzsei, R. Almasi, T. Szuts, G. Keri and Z. Helyes. Analgesic effect of TT-232, a heptapeptide somatostatin analogue, in acute pain models of the rat and the mouse and in streptozotocin-induced diabetic mechanical allodynia. Eur J Pharmacol 498: 103-109 (2004).
23. K. Yashpal and T.J. Coderre. Influence of formalin concentration on the antinociceptive effects of antiinflammatory drugs in the formalin test in rats:seperate mechanisms underlying the nociceptive effects of low and high-concentration formalin. Eur J Pain 2: 63-68 (1998).
24. I.A Bukhari, R.A. Khan, A.H. Gilani, A.J. Shah, J. Hussain, and V.U. Ahmad. The Analgesic, Antiinflammatory and Calcium Antagonist Potential of Tenacetum artemisiodes. Arch Pharm Res 30(3): 303-308 (2007).
25. S. Yano, Y. Suzuki, M. Yuzurihara, Y. Kase, S. Takeda, S. Wantanabe, M. Aburada, and K. Miyamoto. Antinociceptive effect of methyleugenol on formalininduced hyperalgesia in mice. . Eur J Pharmacol 553: 99-103 (2006).
26. + channels by diclofenac. Eur J Pharmacol 438: 85-89 (2002).
27. J. Mino, V. Moscatelli, O. Hnatyszyn, S. Gorzalczany, C. Acevedo and G. Ferraro. Antinociceptice and antiinflammatory activities of Artemisia copa extracts. Pharmacol Res 50: 59-63 (2004).
28. J.H. Rosland, A. Tjolsen, B. Maehle and D.K. Hole. The formalin test in mice. Effect of formalin concentration. Pain 42: 235-242 (1990).
29. S. Amos, L. Binda, H. Vongtau, B. Chindo, J. Abbah, N. Sambo, E.M. Odin, S.K. Okwute, P. Akah, C. Wambebe and K. Gamaniel. Sedative effects of the methanolic leaf extract of Newbouldia laevis in mice and rats. Boll Chim Farm 141(6): 471-475 (2002).
30. J. Sawynok and A. Reid. Antinociception by tricyclic antidepressants in the rat formalin test: differential effects on different behaviours following systemic and spinal administration. Pain 93: 51-59 (2001).
31. R.D. Macpherson. Pharmacological basis of contemporary pain management. Pharmacol Ther 88: 163-185 (2000).
32. J.D. Schim, and P. Stang. Overview of Pain Management. Pain Practice 4(1S): S4-S18 (2004).
33. T.S. Sindrup Jensen. Efficacy of pharmacological treatmments of neuropathic pain: an update and effect related to mechanism of drug action. Pain 83: 389-400 (1999).
34. F., R. Irvine, Woody plants of Ghana. Oxford University Press: London, 1961.
35. B. Oliver-Bever. Medicinal plants in tropical West Africa. Cambridge University Press: Cambridge, 1986.