Is the reduced efficacy of morphine in diabetic rats caused by alterations of opiate receptors or of morphine pharmacokinetics?

Journal of Pharmacology and Experimental Therapeutics

Volumn 285, Issue 1, 1998, Pages 63-70

  Courteix, C ^a   Bourget, P ^a,b   Caussade, F ^a,c   Bardin, M ^a   Coudore, F ^a   Fialip, J ^a   Eschalier, A ^a  

^a UNIVERSITÉ CLERMONT AUVERGNE   (France)

^b INSTITUT GUSTAVE ROUSSY   (France)

^c UPSA Laboratories   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; MORPHINE; MORPHINE 3 GLUCURONIDE; MORPHINE 6 GLUCURONIDE; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR AGONIST; STREPTOZOCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINOCICEPTION; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG RECEPTOR BINDING; HYPERALGESIA; INTRAPERITONEAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT; STREPTOZOCIN DIABETES;

EID: 0031977718     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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