Exercise as an anti-inflammatory intervention to combat inflammatory diseases of muscle

Current Opinion in Rheumatology

Volumn 21, Issue 6, 2009, Pages 599-603

  Nader, Gustavo A ^a   Lundberg, Ingrid E ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Exercise; Inflammation; Myositis; Physical activity; Treatment

Indexed keywords

AZATHIOPRINE; C REACTIVE PROTEIN; GLUCOCORTICOID; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 6; METHOTREXATE;

ANTIINFLAMMATORY ACTIVITY; DRUG MEGADOSE; EXERCISE; HUMAN; INFLAMMATION; MYOSITIS; PATIENT SAFETY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; REVIEW; THERAPY EFFECT; TREATMENT OUTCOME;

CYTOKINES; EXERCISE THERAPY; HUMANS; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION MEDIATORS; MUSCLE, SKELETAL; MYOSITIS;

EID: 70349832897     PISSN: 10408711     EISSN: None     Source Type: Journal    
DOI: 10.1097/BOR.0b013e3283319d53     Document Type: Review

References (33)

1. Brown JA, Elliott MJ, Sray WA. Exercise-induced upper extremity rhabdo-myolysis and myoglobinuria in shipboard military personnel. Mil Med 1994; 159:473-475.
2. Sultan SM, Ioannou Y, Moss K, Isenberg DA. Outcome in patients with idiopathic inflammatory myositis: morbidity and mortality. Rheumatology (Oxford) 2002; 41:22-26.
3. Ponyi A, BorgulyaG, ConstantinT, et al. Functional outcome and quality of life in adult patients with idiopathic inflammatory myositis. Rheumatology (Oxford) 2005; 44:83-88.
4. Alexanderson H. Exercise effects in patients with adult idiopathic inflammatory myopathies. Curr Opin Rheum 2009; 21:158-163.
5. Alexanderson H, Stenstrom CH, Lundberg I. Safety of a home exercise programme in patients with polymyositis and dermatomyositis: a pilot study. Rheumatology (Oxford) 1999; 38:608-611.
6. Alexanderson H, Stenstrom CH, JennerG, et al. The safety of a resistive home exercise program in patients with recent onset active polymyositis or dermatomyositis. Scand J Rheumatol 2000; 29:295-301.
7. Wiesinger GF, Quittan M, Aringer M, et al. Improvement of physical fitness and muscle strength in polymyositis/dermatomyositis patients by a training programme. Br J Rheumatol 1998; 37:196-200.
8. Wiesinger GF, Quittan M, Graninger M, et al. Benefit of 6 months long-term physical training in polymyositis/dermatomyositis patients. Br J Rheumatol 1998; 37:1338-1342.
9. Alexanderson H, Dastmalchi M, Esbjornsson-Liljedahl M, et al. Benefits of intensive resistance training in patients with chronic polymyositis or dermatomyositis. Arthritis Rheum 2007; 57:768-777.
10. Park JH, Vital TL, Ryder NM, et al. Magnetic resonance imaging and P-31 magnetic resonance spectroscopy provide unique quantitative data useful in the longitudinal management of patients with dermatomyositis. Arthritis Rheum 1994; 37:736-746.
11. Dastmalchi M, Alexanderson H, Loell I, et al. Effect of physical training on the proportion of slow-twitch type I muscle fibers, a novel nonimmune-mediated mechanism for muscle impairment in polymyositis or dermatomyositis. Arthritis Rheum 2007; 57:1303-1310.
12. Hakkinen A, Sokka T, Kotaniemi A, Hannonen P. A randomized two-year study of the effects of dynamic strength training on muscle strength, disease activity, functional capacity, and bone mineral density in early rheumatoid arthritis. Arthritis Rheum 2001; 44:515-522.
13. Hakkinen A, Hannonen P, Nyman K, et al. Effects of concurrent strength and endurance training in women with early or longstanding rheumatoid arthritis: comparison with healthy subjects. Arthritis Rheum 2003; 49:789-797.
14. van den EndeCH, Breedveld FC, leCessieS, et al. Effect of intensive exercise on patients with active rheumatoid arthritis: a randomised clinical trial. Ann Rheum Dis 2000; 59:615-621.
15. Vogiatzis I, Stratakos G, Simoes DC, et al. Effects of rehabilitative exercise on peripheral muscle TNFalpha, IL-6, IGF-I and MyoD expression in patients with COPD. Thorax 2007; 62:950-956.
16. Dekker MJ, Lee S, Hudson R, et al. An exercise intervention without weight loss decreases circulating interleukin-6 in lean and obese men with and without type 2 diabetes mellitus. Metabolism 2007; 56:332-338.
17. Chung YL, Alexanderson H, Pipitone N, et al. Creatine supplements in patients with idiopathic inflammatory myopathies who are clinically weak after conventional pharmacologic treatment: six-month, double-blind, randomized, placebo-controlled trial. Arthritis Rheum 2007; 57:694-702.
18. Woods JA, VieiraVJ, Keylock KT. Exercise, inflammation, and innate immunity. Neurol Clin 2006; 24:585-599.
19. Petersen AM, Pedersen BK. The anti-inflammatory effect of exercise. J Appl Physiol 2005; 98:1154-1162.
20. Fischer CP, Berntsen A, Perstrup LB, et al. Plasma levels of interleukin-6 and C-reactive protein are associated with physical inactivity independent of obesity. Scand J Med Sci Sports 2007; 17:580-587.
21. Fischer CP. Interleukin-6 in acute exercise and training: what is the biological relevance? Exerc Immunol Rev 2006; 12:6-33.
22. Olson TP, Dengel DR, Leon AS, Schmitz KH. Changes in inflammatory biomarkers following one-year of moderate resistance training in overweight women. Int J Obestr (Lond) 2007; 31:996-1003.
23. Cannon JG, Fielding RA, Fiatarone MA, et al. Increased interleukin 1 beta in human skeletal muscle after exercise. Am J Physiol 1989; 257:R451-R455.
24. Malm C, Nyberg P, Engstrom M, et al. Immunological changes in human skeletal muscle and blood after eccentric exercise and multiple biopsies. J Physiol 2000; 529:243-262.
25. Gielen S, Adams V, Mobius-Winkler S, et al. Anti-inflammatory effects of exercise training in the skeletal muscle of patients with chronic heart failure. J Am Coll Cardiol 2003; 42:861-868.
26. Greiwe JS, Cheng B, Rubin DC, et al. Resistance exercise decreases skeletal muscle tumor necrosis factor alpha in frail elderly humans. FASEB J 2001; 15:475-482.
27. Nader GA, Dastmalchi M, Alexanderson M, et al. Resistance exercise improves function and reduces the expression of inflammation and fibrosis genes in skeletal muscle of autoimmune myositis patients. FASEB J 2005; 21:921.14.
28. Ostrowski K, RohdeT, Zacho M, et al. Evidence that interleukin-6 is produced in human skeletal muscle during prolonged running. J Physiol 1998; 508:949-953.
29. Steensberg A, van Hall G, Osada T, et al. Production of interleukin-6 in contracting human skeletal muscles can account for the exercise-induced increase in plasma interleukin-6. J Physiol 2000; 529:237-242.
30. Haddad F, Zaldivar F, Cooper DM, Adams GR. IL-6-induced skeletal muscle atrophy. J Appl Physiol 2005; 98:911-917.
31. Serrano AL, Baeza-Raja B, Perdiguero E, et al. Interleukin-6 is an essential regulator of satellite cell-mediated skeletal muscle hypertrophy. Cell Metab 2008; 7:33-44.
32. Nagaraju K, Raben N, Loeffler L, et al. Conditional up-regulation of MHC class I in skeletal muscle leads to self-sustaining autoimmune myositis and myositis-specific autoantibodies. Proc Natl Acad Sci USA 2000; 97: - 9209-9214.
33. Giraldo E, Garcia JJ, Hinchado MD, Ortega E. Exercise intensity-dependent changes in the inflammatory response in sedentary women: role of neuroen docrine parameters in the neutrophil phagocytic process and the pro-/antiinflammatory cytokine balance. Neuroimmunomodulation 2009; 16:237-244.