Intra-articular magnesium sulfate (MgSO4) reduces experimental osteoarthritis and nociception: association with attenuation of N-methyl-d-aspartate (NMDA) receptor subunit 1 phosphorylation and apoptosis in rat chondrocytes

Osteoarthritis and Cartilage

Volumn 17, Issue 11, 2009, Pages 1485-1493

  Lee, C H ^a   Wen, Z H ^b   Chang, Y C ^b   Huang, S Y ^b   Tang, C C ^c   Chen, W F ^d   Hsieh, S P ^e   Hsieh, C S ^e   Jean, Y H ^e  

^a TAIPEI MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

^c NATIONAL PINGTUNG UNIVERSITY   (Taiwan)

^d CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^e PINGTUNG CHRISTIAN HOSPITAL   (Taiwan)

Author keywords

Chondrocyte apoptosis; Magnesium sulfate; NMDA; Nociception; Osteoarthritis

Indexed keywords

MAGNESIUM SULFATE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR 1;

ALLODYNIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CARTILAGE DEGENERATION; CELL METABOLISM; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; FEMUR CONDYLE; HISTOPATHOLOGY; HYPERALGESIA; KNEE OSTEOARTHRITIS; MALE; NOCICEPTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SYNOVITIS; SYNOVIUM; TIBIA; TREATMENT DURATION;

ANIMALS; APOPTOSIS; ARTHRITIS, EXPERIMENTAL; CARTILAGE, ARTICULAR; INJECTIONS, INTRA-ARTICULAR; KNEE JOINT; MAGNESIUM SULFATE; MALE; N-METHYLASPARTATE; OSTEOARTHRITIS, KNEE; RATS; RATS, WISTAR;

EID: 70349781851     PISSN: 10634584     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.joca.2009.05.006     Document Type: Article

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