Apoptosis and nitric oxide in an experimental model of osteoarthritis in rabbit after hyaluronic acid treatment

Journal of Orthopaedic Research

Volumn 23, Issue 6, 2005, Pages 1370-1376

  Díaz Gallego, Luis ^a   Prieto, Julio G ^b   Coronel, Pilar ^c   Gamazo, Luis E ^a   Gimeno, Mercedes ^c   Alvarez, Ana I ^b  

^a Hospital of Leon   (Spain)

^b UNIVERSITY OF LEÓN   (Spain)

^c Tedec Meiji Farma SA   (Spain)

Author keywords

Apoptosis; Articular cartilage; Chondrocyte; Nitric oxide; Osteoarthritis; Rabbit; Viscosupplementation

Indexed keywords

ANNEXIN; HYALURONIC ACID; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTERIOR CRUCIATE LIGAMENT; APOPTOSIS; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; DISEASE COURSE; DRUG MECHANISM; FLOW CYTOMETRY; KNEE OSTEOARTHRITIS; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RABBIT;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; APOPTOSIS; CARTILAGE; DISEASE MODELS, ANIMAL; HYALURONIC ACID; IN SITU NICK-END LABELING; NITRIC OXIDE; OSTEOARTHRITIS; RABBITS;

EID: 27644512849     PISSN: 07360266     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.orthres.2005.05.003     Document Type: Article

References (31)

1. N. Adam P. Ghosh Hyaluronan molecular weight and polydispersity in some commercial intra-articular injectable preparations and in synovial fluid Inflamm Res 50 2001 294-299
2. S. Aihara N. Mukakami R. Ishii K. Kariya Y. Azuma K. Hamada et al. Effects of sodium hyaluronate on the nociceptive response of rats with experimentally induced arthritis Nippon Yakurigaku Zasshi Folia Pharmacol Jpn 100 1992 359-365
3. American College of Rheumatology. Subcomittee on Osteoarthritis Guidelines: Recommendations for the medical management of osteoarthritis of the hip and knee. Arthritis Rheum 2000;43:1905-15.
4. A.R. Amin P.E. Di Cesare P. Vyas M. Attur E. Tzeng T.R. Billiar et al. The expression and regulation of nitric oxide synthase in human osteoarthritis-affected chondrocytes: Evidence for up-regulated neuronal nitric oxide synthase J Exp Med 182 1995 2097-2102
5. E.A. Balazs S. Briller J.L. Denlinger Na-hyaluronate molecular size variations in equine and human arthritic synovial fluids and the effect on phagocycit cells Semin Arthritis Rheum 11 1981 141-143
6. E.A. Balazs J.L. Denlinger Viscosupplementation: A new concept in the treatment of osteoarthritis J Rheum Suppl 39 1993 3-9
7. F.J. Blanco R. Guitian E. Vázquez-Martul F. De Toro F. Galdo Chondrocytes OA die by apoptosis: A possible explanation for ethiopathogenesis of OA Arthritis Rheum 38 1998 540-545
8. F.J. Blanco R. Guitian E. Vazquez-Martul F.J. de Toro F. Galdo Osteoarthritis chondrocytes die by apoptosis. A possible pathway for osteoarthritis pathology Arthritis Rheum 41 1998 284-289
9. T.H. Conrozier Death of articular chondrocytes. Mechanism and protection Presse Med 27 1998 1859-1861
10. S.P. Frean L.A. Abraham P. Lees In vitro stimulation of equine articular cartilage proteoglycan synthesis by hyaluronan and carprofen Res Vet Sci 67 1999 183-190
11. A.L. Granger N.M. Anstey W.C. Miller Measuring NO in human clinical studies Methods Enzymol 301 1999 50-61
12. S. Hashimoto K. Takahashi D. Amiel R.D. Coutts M. Lotz Chondrocyte apoptosis and nitric oxide production during experimentally induced osteoarthritis Arthritis Rheum 41 1998 1266-1274
13. J.R. Kirwan E. Rankin Intra articular therapy in osteoarthritis Baillieres Clin Rheum 11 1997 769-794
14. K. Kobayashi M. Amiel F.L. Harwood R.M. Healey M. Sonoda H. Moriya et al. The long term effects of hyaluronan during development of osteoarthritis following partial meniscectomy in a rabbit model Osteoarthr Cartillage 8 2000 359-365
15. S. Komatsu H. Iwata T. Nabeshima Studies on the kinetics, metabolism and re-utilisation after intra-articular administration of hyaluronan to rabbits Arzneimittelforschung 49 1999 427-433
16. L. Kuritzky A. Weaver Advances in rheumatology: Coxibs and beyond J Pain Symptom Manage 25 2003 S6-S19
17. U.B.G. Laurent J.R.E. Fraser A. Amstrong-Laurent R.K. Reed L.B. Dahl T.C. Saurent Catabolism of hyaluronan in the knee joint of the rabbit Matrix 12 1992 130-136
18. L.W. Moreland Intra-articular hyaluronan (hyaluronic acid) and hylans for the treatment of osteoarthritis: Mechanism of action Arthritis Res Ther 5 2003 54-67
19. J. Pelletier D. Jovanovic J. Fernandes P. Manning Reduced progression of experimental osteoarthritis in vivo by selective inhibition of inducible nitric oxide synthase Arthritis Rheum 41 1998 1275-1286
20. M.A. Pozo E.A. Balazs C. Belmonte Reduction of sensory responses to passive movements of inflamed knee joints by hylan, a hyaluronic derivative Exp Brain Res 116 1997 3-9
21. J.A. Roman J. Chismol M. Morales J.L. Donderis Intra-articular treatment with hyaluronic acid. Comparative study of hyalgan and adant Clin Rheum 19 2000 204-206
22. R.L. Sah A.S. Yang A.C. Chen J.J. Hant R.B. Halili M. Yoshioka et al. Physical properties of rabbit articular cartilage after transection of the anterior cruciate ligament J Orthopaed Res 15 1997 197-203
23. Y. Sakakubara T. Miura H. Iwata T. Kikuchi T. Yamaguchi T. Yoshimi et al. Effect of high-molecular-weight sodium hyaluronate on immobilized rabbit knee Clin Orthop 299 1994 282-292
24. C. Shimizu M. Yoshioka Rd. Coutts Fl. Harwood T. Kubo Y. Hirasawa et al. Long-term effects of hyaluronan on experimental osteoarthritis in the rabbit knee Osteoarthr Cartillage 6 1998 1-9
25. J.F. Simpson P.L. Dutt D.L. Page Expression of mitoses per thousand cells and cell density in breast carcinomas: A proposal Hum Pathol 23 1992 608-611
26. K. Takahashi R.S. Goomer F. Harwood T. Kubo Y. Hirasawa D. Amiel The effects of hyaluronan on matrix metalloproteinase-3 (MMP-3), interleukin-1beta (IL-1beta), and tissue inhibitor of metalloproteinase-1 (TIMP-1) gene expression during the development of osteoarthritis Osteoarthr Cartillage 7 1999 182-190
27. K. Takahashi S. Hashimoto T. Kubo Y. Hirasawa M. Lotz D. Amiel Effect of hyaluronan on chondrocyte apoptosis and nitric oxide production in experimentally induced osteoarthritis J Rheum 27 2000 1713-1720
28. K. Takahashi S. Hashimoto T. Kubo Y. Hirasawa M. Lotz D.H. Amiel Hyaluronan suppressed nitric oxide production in the meniscus and synovium of rabbit osteoarthritis model J Orthop Res 19 2001 500-503
29. J.M. Williams V. Rayan D.R. Sumner E.J-MA. Thonar The use of intra-articular Na-hyaluronate as a potential chondroprotective device in experimentally induced articular cartilage injury and repair in rabbits J Orthop Res 21 2003 305-311
30. M. Yoshioka R.D. Coutts D. Amiel S.A. Hacker Characterization of a model of osteoarthritis in the rabbit knee Osteoarthr Cartillage 4 1996 87-98
31. M. Yoshioka C. Shimizu F.L. Harwood R.D. Coutts D. Amiel The effects of hyaluronan during the development of osteoarthritis Osteoarthr Cartillage 5 1997 257-260