Cross-talk between inducible nitric oxide synthase and cyclooxygenase in Helicobacter-pylori-induced gastritis

Medical Principles and Practice

Volumn 18, Issue 6, 2009, Pages 477-481

  Franco, L ^a   Talamini, G ^a  

^a UNIVERSITY OF VERONA   (Italy)

Author keywords

Cyclooxygenase 2; Gastric mucosa; Helicobacter pylori; Inducible nitric oxide synthase; Nitric oxide; Prostaglandin

Indexed keywords

CYCLOOXYGENASE 2; INDUCIBLE NITRIC OXIDE SYNTHASE; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; N [3 (AMINOMETHYL)BENZYL]ACETAMIDINE; PROSTAGLANDIN E2; PROSTAGLANDIN SYNTHASE;

ARTICLE; CLINICAL ARTICLE; ENZYME ACTIVATION; ENZYME ACTIVITY; FEMALE; HELICOBACTER INFECTION; HUMAN; HUMAN TISSUE; MALE; PROTEIN EXPRESSION; STOMACH BIOPSY; WESTERN BLOTTING;

ACTINS; CASE-CONTROL STUDIES; CYCLOOXYGENASE 2; DINOPROSTONE; FEMALE; GASTRIC MUCOSA; GASTRITIS; HELICOBACTER INFECTIONS; HUMANS; MALE; NITRIC OXIDE SYNTHASE TYPE II;

EID: 70349742210     PISSN: 10117571     EISSN: None     Source Type: Journal    
DOI: 10.1159/000235898     Document Type: Article

References (22)

1. Tsutsumi S, Tomisato W, Takano T, Rokutan K, Tsuchiya T, Mizushima T: Gastric irritants induce apoptosis in guinea pig gastric mucosal cells in primary culture. Biochim Biophys Acta 2002; 1589: 168-180. (Pubitemid 34463084)
2. Konturek SJ: The physiological role of prostaglandins in cytoprotection; in Cheli R (ed): Gastric Protection. New York, Raven Press, 1988, p 13.
3. Whittle BJR, Lopez-Belmonte J, Moncada S: Regulation of gastric mucosal integrity by endogenous nitric oxide: interactions with prostanoids and sensory neuropeptides in the rat. Br J Pharmacol 1990; 99: 607-611. (Pubitemid 20069172)
4. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: physiology, pathophysiology and pharmacology. Pharmacol Rev 1991; 43: 109-142.
5. Dubois RN, Abramson SB, Crofford L, Gupta RA, Simon LS, Van de Putte LB, Lipsky PE: Cyclooxygenase in biology and disease. FASEB J 1998; 12: 1063-1073.
6. Fischer H, Becker JC, Boknik P, Huber V, Lüss H, Neumann J, Schmitz W, Domschke W, Stachura J, Kunturek JW: Expression of constitutive nitric oxide synthase in rat and human gastrointestinal tract. Biochim Biophys Acta 1999; 1450: 414-422. (Pubitemid 29295491)
7. Garcia-Vitoria M, Garcia-Corchon C, Rodriguez JA, Garcia-Amigot F, Burrell MA: Expression of neuronal nitric oxide synthase in several types of the rat gastric epithelium. J Histochem Cytochem 2000; 48: 1111-1119. (Pubitemid 30640195)
8. Ambs S, Hussain SP, Harris CC: Interactive effects of nitric oxide and the p53 tumor suppressor gene in carcinogenesis and tumor progression. FASEB J 1997; 11: 443-448. (Pubitemid 27259985)
9. 2+- independent nitric oxide synthase activity in rat gastric mucosal cells. Eur J Pharmacol 1994; 292: 111-114.
10. Franco L, Doria D: Nitric oxide enhances prostaglandin production in ethanol-induced gastric mucosal injury in rats. Eur J Pharmacol 1998; 348: 247-256. (Pubitemid 28275589)
11. Boughton-Smith NK, Evans SM, Laszlo F, Whittle BJR, Moncada S: The induction of nitric oxide synthase and intestinal vascular permeability by endotoxin in the rat. Br J Pharmacol 1993; 110: 1189-1195. (Pubitemid 24005259)
12. Tepperman BL, Soper BD: Nitric oxide synthase induction and cytoprotection of rat gastric mucosa from injury by ethanol. Can J Physiol Pharmacol 1994; 72: 1308-1312.
13. Wallace JL, Miller MJ: Nitric oxide in mucosal defense: a little goes a long way. Gastroenterology 2000; 119: 512-520.
14. Parsonnet J, Hansen S, Rodriguez L, Gelb AB, Warnke RA, Jellum E, Orentreich N, Vogelman JH, Friedmam GD: Helicobacter pylori infection and gastric lymphoma. N Engl J Med 1994; 330: 1267-1271.
15. Mannick EE, Bravo LE, Zarama G, Realpe JL, Zhang XJ, Ruiz B, Fontham ETH, Mera R, Miller MJS, Correa P: Inducible nitric oxide synthase, nitrotyrosine, and apoptosis in Helicobacter pylori gastritis: effect of antibiotics and antioxidants. Cancer Res 1996; 56: 3238-3243.
16. Dixon MF, Genta MG, Yardley JH, Pelay C: Classification and grading of gastritis. Am J Surg Pathol 1996; 20: 1161-1181.
17. Enzyme immunoassay prostaglandin E metabolite EIA kit. Ann Arbor, Cayman Chemical Company, 2004.
18. Bradford MM: A rapid and sensitive method for the quantitation of microgram quantitites of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248-254.
19. Franco L, Talamini G, Carra G, Doria D: Expression of COX-1, COX-2, and inducible nitric oxide synthase protein in human gastric antrum with Helicobacter pylori infection. Prostaglandins Other Lipid Mediat 1999; 58: 9-17.
20. Surh YJ, Chun KS, Cha HH, Han SS, Keum YS, Park KK, Lee SS: Molecular mechanisms underlying chemopreventive activities of anti-inflammatory phytochemicals: down-regulation of COX-2 and iNOS through suppression of NF-kappa B activation. Mutat Res 2001; 480-481: 243-268.
21. Beyaert R (ed): Nuclear Factor κB: Regulation and Role in Disease. Dordrecht, Kluwer Academic Publishers, 2003.
22. Goodwing DC, Landino LM, Marnett LJ: Effects of nitric oxide and nitric oxide-derived species on prostaglandin endoperoxide synthase and prostaglandin biosynthesis. FASEB J 1999; 13: 1121-1136. (Pubitemid 29300359)