Population structure of Plasmodium falciparum gametocyte sex ratios in malarious children in an endemic area

Parasitology International

Volumn 58, Issue 4, 2009, Pages 438-443

  Sowunmi, Akintunde ^a   Gbotosho, Grace O ^a   Happi, Christian T ^a   Folarin, Onikepe A ^a   Balogun, Sulayman T ^a  

^a UNIVERSITY OF IBADAN   (Nigeria)

Author keywords

Antimalarials; Children; Gametocytes; Nigeria; P. falciparum; Sex ratio; Transmission

Indexed keywords

AMODIAQUINE PLUS ARTESUNATE; AMODIAQUINE PLUS SULFALENE PYRIMETHAMINE; ANTIMALARIAL AGENT; ARTEMETHER PLUS BENFLUMETOL; ARTEMISININ; ARTESUNATE; CHLOROQUINE; COTRIMOXAZOLE; DEETHYLAMODIAQUINE; FANSIDAR; MEROZOITE SURFACE PROTEIN 1; MEROZOITE SURFACE PROTEIN 2; PROBENECID; UNCLASSIFIED DRUG;

ADOLESCENT; ANEMIA; ARTICLE; CHILD; CHILDHOOD DISEASE; FEMALE; GAMETOCYTE; GENETIC VARIABILITY; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MOLECULAR CLONING; MONOTHERAPY; NIGERIA; PLASMODIUM FALCIPARUM; POLYMERASE CHAIN REACTION; PRESCHOOL CHILD; PRIORITY JOURNAL; SCHOOL CHILD; SEX RATIO;

ADOLESCENT; ANIMALS; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; ENDEMIC DISEASES; FEMALE; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; NIGERIA; PLASMODIUM FALCIPARUM; SEX RATIO;

PLASMODIUM FALCIPARUM;

EID: 70349730229     PISSN: 13835769     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.parint.2009.08.007     Document Type: Article

References (36)

1. Sinden R.E. Sexual development of malaria parasites. Adv Parasitol 22 (1983) 153-216
2. Pickering J., Read A.F., Guerrero S., and West S.A. Sex ratio and virulence in two species of lizard malaria parasites. Evol Ecol Res 2 (2000) 171-184
3. West S.A., Reece S.E., and Read A.F. Evolution of gametocyte sex ratios in malaria and related apicomplexan (protozoan) parasites. Trends Parasitol 17 (2001) 525-531
4. West S.A., Smith T.G., Nee S., and Read A.F. Fertility insurance and the sex ratios of malaria and related hemosporin blood parasites. J Parasitol 88 (2002) 258-263
5. Sinden R.E., Canning E.U., Bray R.S., and Smalley M.E. Gametocytes and gamete development in Plasmodium falciparum. Proc R Soc Lond Ser B 201 (1978) 375-399
6. Hamilton W.D. Extraordinary sex ratios. Science 156 (1967) 477-481
7. Reece S.E., Drew D.R., and Gardner A. Sex ratio adjustment and kin discrimination in malaria parasites. Nature 453 (2008) 609-614
8. Paul R.E.L., Coulson T.N., Raibaud A., and Brey P.T. Sex determination in malaria parasites. Science 287 (2000) 128-131
9. Robert V., Sokhna C.S., Rogier C., Ariey F., and Trape J.F. Sex ratio of Plasmodium falciparum gametocytes in inhabitants of Dielmo, Senegal. Parasitol 127 (2003) 1-8
10. Reece S.E., Duncan A.B., West S.A., and Read A.F. Host cell preference and variable transmission strategies in malaria parasites. Proc R Soc Lond Ser B 272 (2005) 511-517
11. Salako L.A., Ajayi F.O., Sowunmi A., and Walker O. Malaria in Nigeria: a revisit. Ann Trop Med Parasitol 84 (1990) 435-445
12. Happi C.T., Gbotosho G.O., Falade C.O., Akinboye D.O., Gerena L., Hudson T., et al. Point mutation in the pfcrt and pfmdr-1 genes of Plasmodium falciparum and clinical response to chloroquine among malaria patients from Nigeria. Ann Trop Med Parasitol 97 (2003) 439-451
13. Happi C.T., Gbotosho G.O., Sowunmi A., Falade C.O., Akinboye D.O., Hudson T., et al. Molecular analysis of Plasmodium falciparum recrudescent malaria infections in children treated with chloroquine in Nigeria. Am J Trop Med Hyg 70 (2004) 20-26
14. Happi C.T., Gbotosho G.O., Folarin O.A., Bolaji O.M., Sowunmi A., Kyle D.E., et al. Association between mutations in pfcrt and pfmdr-1 genes and in vivo amodiaquine resistance in falciparum malaria-infected children in Nigeria. Am J Trop Med Hyg 75 (2006) 155-161
15. Sowunmi A., Balogun T., Gbotosho G.O., Happi C.T., Adedeji A.A., and Fehintola F.A. Activities of amodiaquine, artesunate, and artesunate-amodiaquine against asexual- and sexual-stage parasites in falciparum malaria in children. Antimicrob Agents Chemother 51 (2007) 1694-1699
16. Sowunmi A., Balogun T., Gbotosho G.O., Happi C.T., Adedeji A.A., Bolaji O.M., et al. Activities of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine against sexual-stage parasites in falciparum malaria in children. Chemother 54 (2008) 201-208
17. Sowunmi A., Balogun S.T., Gbotosho G.O., and Happi C.T. Plasmodium falciparum gametocyte sex ratios in children with acute, symptomatic, uncomplicated infections treated with amodiaquine. Malaria J 7 (2008) 169
18. World Health Organization. Severe falciparum malaria. Trans R Soc Trop Med Hyg 94 Suppl 1 (2000) 1-90
19. Sowunmi A., and Fateye B.A. Plasmodium falciparum gametocytaemia in Nigerian children: before, during and after treatment with antimalarial drugs. Trop Med Inter Health 8 (2003) 783-792
20. Sowunmi A., Gbotosho G.O., Happi C.T., Adedeji A.A., Fehintola F.A., Folarin O.A., et al. Therapeutic efficacy and effects of artemether-lumefantrine and amodiaquine-sulfalene-pyrimethamine on gametocyte carriage in children with uncomplicated Plasmodium falciparum malaria in southwestern Nigeria. Am J Trop Med Hyg 77 (2007) 235-241
21. Carter R., and Graves P.M. Gametocytes. In: Wernsdorfer W.H., and McGregor I. (Eds). Malaria: principles and practice of malariology Vol I (1988), Churchill Livingstone, Edinburgh 253-303
22. Epi Info version 6. A word processing data base and statistics program for public health on IBM-compatible microcomputers (1994), Centers for Disease Control and Prevention, Atlanta, GA
23. SPSS for Windows release 10.01 (standard version) (1999), SPSS Inc, Chicago, IL, USA
24. Sowunmi A., Balogun S.T., Gbotosho G.O., and Happi C.T. Plasmodium falciparum sex ratios in acutely symptomatic children treated with antimalarial drugs. Acta Tropica 109 (2009) 108-117
25. Read A.F., Narara A., Nee S., Keymer A.E., and Day K.P. Gametocyte sex ratios as indirect measures of outcrossing rates in malaria. Parasitol 104 (1992) 387-395
26. Nee S., West S.A., and Read A.F. Inbreeding and parasite sex ratios. Proc R Soc Lond Series B 269 (2002) 755-760
27. West S.A., Smith T.G., and Read A.F. Sex allocation and population structure in apicomplexan (protozoa) parasites. Proc R Soc Lond Series B 267 (2000) 257-263
28. Robert V., Read A.F., Essong J., Tchuinkam T., Mulder B., Verhave J.P., et al. Effects of gametocyte sex ratio on infectivity of Plasmodium falciparum to Anopheles gambiae. Trans R Soc Trop Med Hyg 90 (1996) 621-624
29. Werren L.H., Nur U., and Wu C.-I. Selfish genetic elements. Trends Ecol Evol 3 (1988) 297-302
30. Paul R.E.L., Packer M.J., Walmsley M., Lagog M., Randford-Cartwright L.C., Paru R., et al. Mating patterns in malaria parasite populations of Papua New Guinea. Science 269 (1995) 1709-1711
31. Price R.N., Nosten F., Luxemburger C., ter Kuile K.O., Paiphun L., Chongsuphajasiddhi T., et al. Effects of artemisinin derivatives on malaria transmissibility. Lancet 347 (1996) 1654-1658
32. Drew D.R., and Reece S.E. Development of reverse-transcription PCR techniques to analyse the density and sex ratio of gametocytes in genetically diverse Plasmodium chabaudi infections. Mol Biochem Parasitol 156 (2007) 199-209
33. Sowunmi A., Balogun S.T., Gbotosho G.O., and Happi C.T. Effects of amodiaquine, artesunate, artesunate-amodiaquine on Plasmodium falciparum associated anaemia in children. Acta Tropica 109 (2009) 55-60
34. Sowunmi A., Balogun S.T., Gbotosho G.O., and Happi C.T. Influence of anaemia on Plasmodium falciparum gametocyte sex ratios in acutely symptomatic children. The Open Trop Med J 1 (2008) 13-20
35. Crawley J. Reducing the burden of anemia in infants and young children in malaria-endemic countries of Africa: from evidence to action. Am J Trop Med Hyg 71 (2004) 25-34
36. Price R.N., Nosten F., Simpson J.A., Luxemburger C., Paiphun L., ter Kuile T.O., et al. Risk factors for gametocyte carriage in uncomplicated falciparum malaria. Am J Trop Med Hyg 60 (1999) 1019-1023